Observations on the efficacy of combined acupuncture and medicine in Treating 50 cases of pseudobulbar paralysis

目的：观察针药结合治疗假性延髓麻痹的疗效。方法：采用完全随机抽样法分为针刺组50例，对照组48例。针刺组在西医治疗的同时，应用针刺进行综合治疗；对照组单纯接受西医药物治疗。结果：针刺组有效率为92．0％，对照组为62．5％。两组疗效差异具有非常显著性意义（P〈0．01）。结论：针药结合治疗假性延髓麻痹效果明显优于单纯西药治疗。     

Pharmacological therapy of vascular malformations of the gastrointestinal tract.

Vascular malformation (AVM) in the gastrointestinal tract is an uncommon, but not rare, cause of bleeding and iron deficiency anemia, especially in an aging population. While endoscopic coagulative therapy is the method of choice for controlling bleeding, a substantial number of cases require additional therapy. Adjunctive or even primary phamacotherapy may be indicated in recurrent bleeding. However, there is little evidence-based proof of efficacy for any agent. The bulk of support is derived from anecdotal reports or case series. The present review compares the outcome of AVM after no intervention, coagulative therapy or focus on pharmacological agents. Most of the literature encompasses two common AVMs, angiodysplasia and hereditary hemorrhagic telangiectasia. Similarly, the bulk of information evaluates two therapies, hormones (estrogen and progesterone) and the somatostatin analogue octreotide. Of these, the former is the only therapy evaluated in randomized trials, and the results are conflicting without clear guidelines. The latter therapy has been reported only as case reports and case series without prospective trials. In addition, other anecdotally used medications are discussed.     

患肢注射高浓度尿激酶治疗下肢深静脉血栓形成45例报告

探讨下肢深静脉血栓的溶栓治疗与疗效。方法 :经患肢注射尿激酶每日 75万单位溶栓治疗 4 5例下肢深静脉血栓形成。结果 :病程在 2周内溶栓治愈 72 % (18/2 5 ) ,有效率 10 0 % (2 5 /2 5 ) ,病程超过 2周溶栓治愈率 30 % (6 /2 0 ) ,有效率 85 % (17/2 0 ) ,治疗过程无出血倾向。结论 :溶栓时间越早效果越好 ,经患肢注射尿激酶的增加局部的药物浓度而且药物用量可增大     

三维立体培养法诱导去分化软骨细胞Ⅱ型胶原的重新表达

目的用藻酸盐三维立体培养法及离心管聚集体诱导培养法促进去分化的永生化软骨细胞第50代(IHACs50)重新表达软骨细胞的Ⅱ型胶原标志性表型。方法利用藻酸盐三维立体培养法以及离心管聚集体诱导培养法分别诱导培养去分化的永生化人关节软骨细胞第50代,然后用Ⅰ、Ⅱ、Ⅲ型胶原的免疫组织化学染色、Ⅱ型胶原的逆转录-聚合酶链反应(RT-PCR)检测、激光共聚焦显微镜检测、胶原定量检测该永生化软骨细胞的Ⅱ型胶原表型表达情况。结果免疫组织化学染色、激光共聚焦显微镜检测、RT-PCR检测分别提示藻酸盐三维立体培养法和离心管聚集体诱导培养法使去分化永生化人关节软骨细胞的Ⅱ型胶原染色阳性以及621 bp的Ⅱ型胶原mR- NA表达,Western blot和3H-脯氨酸标记SDS-PAGEⅡ型胶原定量检测发现前者促进Ⅱ型胶原分泌较后者多。结论去分化永生化人关节软骨细胞可以经不同的诱导方法而重新表达Ⅱ型胶原表型,藻酸盐三维立体培养法因与软骨细胞的生理环境相似,故促进Ⅱ型胶原重新表达较多。     

略述中医刺血术发展史

刺血术是中医学中一种古老而独特的针刺治疗方法，文章对刺血术的发展进行了概述，并对其历史分期进行了总结。刺血术发展的四个历史阶段是：第一阶段为起源及萌芽阶段(春秋以前)，以砭石的出现及其应用标志；第二阶段为理论奠基及经验积累阶段(战国至唐)，以《黄帝内经》的问世为其理论体系形成标志；第三阶段为理论创新及特色形成阶段(宋金元)，以金元四大家刘完素、张从正、李杲、朱震亨的刺血成就为其代表；第四阶段为不断完善及日趋成熟阶段(明清)，以诸医家对瘟毒疫疠的刺血经验为其特征。