全文获取类型
收费全文 | 3412篇 |
免费 | 222篇 |
国内免费 | 59篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 111篇 |
妇产科学 | 112篇 |
基础医学 | 266篇 |
口腔科学 | 32篇 |
临床医学 | 270篇 |
内科学 | 694篇 |
皮肤病学 | 74篇 |
神经病学 | 274篇 |
特种医学 | 41篇 |
外国民族医学 | 1篇 |
外科学 | 231篇 |
综合类 | 520篇 |
预防医学 | 323篇 |
眼科学 | 27篇 |
药学 | 344篇 |
2篇 | |
中国医学 | 126篇 |
肿瘤学 | 223篇 |
出版年
2024年 | 4篇 |
2023年 | 65篇 |
2022年 | 95篇 |
2021年 | 131篇 |
2020年 | 156篇 |
2019年 | 134篇 |
2018年 | 138篇 |
2017年 | 120篇 |
2016年 | 156篇 |
2015年 | 122篇 |
2014年 | 245篇 |
2013年 | 276篇 |
2012年 | 196篇 |
2011年 | 212篇 |
2010年 | 174篇 |
2009年 | 158篇 |
2008年 | 128篇 |
2007年 | 135篇 |
2006年 | 143篇 |
2005年 | 111篇 |
2004年 | 111篇 |
2003年 | 96篇 |
2002年 | 62篇 |
2001年 | 52篇 |
2000年 | 48篇 |
1999年 | 42篇 |
1998年 | 34篇 |
1997年 | 32篇 |
1996年 | 32篇 |
1995年 | 27篇 |
1994年 | 33篇 |
1993年 | 19篇 |
1992年 | 28篇 |
1991年 | 22篇 |
1990年 | 15篇 |
1989年 | 8篇 |
1988年 | 14篇 |
1987年 | 10篇 |
1986年 | 14篇 |
1985年 | 12篇 |
1984年 | 14篇 |
1983年 | 8篇 |
1982年 | 9篇 |
1981年 | 10篇 |
1980年 | 8篇 |
1979年 | 5篇 |
1978年 | 4篇 |
1977年 | 6篇 |
1975年 | 6篇 |
1972年 | 5篇 |
排序方式: 共有3693条查询结果,搜索用时 15 毫秒
1.
Rafiye Ciftciler Haluk Demiroglu Yahya Buyukasık Elifcan Aladag Salih Aksu Ibrahim C. Haznedaroglu Nilgun Sayınalp Osman Ozcebe Umit Yavuz Malkan Hakan Goker 《Clinical Lymphoma, Myeloma & Leukemia》2019,19(3):177-182
Background
Refractory acute myeloid leukemia (AML) includes AML includes failure of disease to respond to standard induction chemotherapy, relapse within 6 months after first CR, and 2 or more relapses. The outcome of these patients is usually very poor; only a small proportion can be rescued by allogenic hematopoietic stem-cell transplantation (allo-HSCT). The aim of this study was to evaluate the efficacy and feasibility of allo-HSCT in patients with refractory AML.Patients and Methods
We retrospectively analyzed the clinical outcome of 91 patients who were diagnosed with treatment-refractory AML at Hacettepe University Hospital between January 2002 and June 2018. Patients' disease status included refractory AML, defined as failure to respond to standard induction chemotherapy and relapse within 6 months after first complete remission.Results
The median follow-up was 12 months (range, 0.5-184 months) for the entire group. Kaplan-Meier estimates of the 3-year overall survival for patients who underwent allo-HSCT and patients who received only salvage chemotherapy were 67% and 12%, respectively. Additionally, the Kaplan-Meier estimates of 5-year overall survival for patients who underwent allo-HSCT and patients who received only salvage chemotherapy were 44% and 4%, respectively (P < .001). Complete remission was obtained in 25 patients (83.3%) who underwent allo-HSCT; however, the disease of only 3 patients (3.8%) exhibited complete response after salvage chemotherapy.Conclusion
Allo-HSCT is still the best-known treatment option with curative potential in patients with treatment-refractory AML. Therefore, all efforts should be made in an attempt to find a suitable matched donor in order to perform allo-HSCT. 相似文献2.
3.
Hiroto Kinoshita Hitomi Nishioka Aya Ikeda Kyoko Ikoma Yoichi Sameshima Hidehisa Ohi Mizuki Tatsuno Junka Kouyama Chiaki Kawamoto Tomohiro Mitsui Yuko Tamura Yu Hashimoto Masashi Nishio Tsuyoshi Ogashiwa Yusuke Saigusa Shin Maeda Hideaki Kimura Reiko Kunisaki Kazuhiko Koike 《Journal of gastroenterology and hepatology》2019,34(11):1929-1939
4.
目的 应用Meta分析的方法评价进展期霍奇金病经化疗达完全缓解后巩固放疗的作用。材料和方法 在MEDLINE、CBMdisc数据库检索进展期霍奇金病化疗达完全缓解行巩固性放疗或不行巩固性放疗的前瞻性随机对照研究。对入选研究的总生存、无事件生存优势比进行Meta分析。结果 4项研究入选,以α=0.05为检验水准,巩固性放疗组与对照组(不作巩固性放疗)相比,5年总生存优势比=1.18,P=0.46;5年无事件生存优势比=1.05.P=0.83:巩固性侵犯野放疗组与对照组相比,5年总生存优势比=0.96,P=0.87。结论 进展期霍奇金病经化疗达到完全缓解后,巩固性放疗对总生存及无事件生存均无益处。 相似文献
5.
6.
人工流产(简称人流)是各种避孕失败的主要补救措施,目前早孕妇女人流的主要方式有吸刮术与药物流产两种。本文通过对天津市黄河医院意外早孕妇女选择人流方式意向的临床调查研究,探讨现阶段该两种人流方式的可接受性,结果:1000例早孕妇女中选择药物流产(简称药流)者666例(66.6%),吸刮术者334例(33.4%)。本组选择人流方式的理由,其中519例(51.9%)认为药流痛苦少,占第一位,认为手术干脆而选择吸刮术的217例(21.7%),占第二位,其它依次为吸刮术费用低、药流不必手术、吸刮术流产完全、药流不需请假、吸刮术出血时间短、药流安全、吸刮术副作用少、药流保密。药流是近年来使用的流产新方法,本组研究资料及意向选择只反映现阶段早孕妇女的接受状况。 相似文献
7.
C Yimin Y Wei C Weidong W Xianmi W Junqing L Lin 《International journal of gynaecology and obstetrics》2004,84(3):229-235
OBJECTIVES: To assess the effect of a medically induced abortion (MA) on birth weight in the first subsequent pregnancy. METHODS: Pregnant women who had had a MA, a surgical abortion (SA), or primigravidas with no history of abortion (NA), were recruited for a prospective cohort study between July 1998 and February 2001. The sample for the present analysis included 12995 singleton live births at term. RESULTS: The overall incidence rate of low birth weight (LBW) was 1.0%. The rates of LBW in the MA, SA, and NA groups were 1.0%, 0.9%, and 1.2, respectively. There were no significant differences in LBW rates between the MA and SA groups, neither between the MA and NA. Logistic regression analysis was used to estimate the effects of MA on birth weight, and we found no relationship between risk of LBW and MA. CONCLUSIONS: We did not find a statistically significant relationship between a history of one medically induced abortion and LBW for the first subsequent term pregnancy. 相似文献
8.
Prediction of Remission of Acute Posttraumatic Stress Disorder in Motor Vehicle Accident Victims 总被引:1,自引:0,他引:1
Edward B. Blanchard Edward J. Hickling Catherine A. Forneris Ann E. Taylor Todd C. Buckley Warren R. Loos James Jaccard 《Journal of traumatic stress》1997,10(2):215-234
One hundred forty five individuals who sought medical attention as a result of a motor vehicle accident (MVA), and who were initially assessed 1 to 4 months post-MVA, were followed up prospectively for 6 months to determine how many of the 55 with posttraumatic stress disorder (PTSD) and the 43 with sub-syndromal PTSD would remit and what variables would predict remission. Thirty (55%) of those with initial PTSD had remitted at least in part by 6 months while 67% of those with sub-syndromal PTSD had remitted (and 5% had worsened). Four variables, including severity of initial symptoms, degree of initial physical injury, relative degree of physical recovery by 4 months and whether a close family member suffered a trauma during the follow-up interval, combined to classify 6-month clinical status of 84% of those with initial PTSD secondary to MVAs. 相似文献
9.
79例人流术后支原体感染分析 总被引:6,自引:0,他引:6
79例人流术后支原体感染分析陆海音,杨红英,周曾娣,张明秋,汤国民Analysisofkycoplasmasinfectionsin79womenwithinduceiabortionLuHai-yin,yangHong-yin,ZhouZeng-d... 相似文献
10.
<正>This is a review of current situation of induced abortion and post abortion family planning service in China. Induced abortion is an important issue in reproductive health. This article reviewed the distribution of induced abortion in various time, areas, and population in China, and explored the character, reason, and harm to reproductive health of induced abortion. Furthermore, this article introduces the concept of Quality of Care Program in Family Planning, and discusses how important and necessary it is to introduce Quality of Care Program in Family Planning to China. 相似文献