全文获取类型
收费全文 | 55篇 |
免费 | 2篇 |
专业分类
基础医学 | 2篇 |
口腔科学 | 1篇 |
临床医学 | 7篇 |
内科学 | 4篇 |
皮肤病学 | 1篇 |
神经病学 | 1篇 |
特种医学 | 1篇 |
外科学 | 4篇 |
综合类 | 9篇 |
预防医学 | 2篇 |
眼科学 | 2篇 |
药学 | 9篇 |
中国医学 | 10篇 |
肿瘤学 | 4篇 |
出版年
2023年 | 1篇 |
2021年 | 2篇 |
2020年 | 3篇 |
2018年 | 1篇 |
2017年 | 3篇 |
2016年 | 2篇 |
2015年 | 2篇 |
2014年 | 1篇 |
2013年 | 4篇 |
2012年 | 1篇 |
2011年 | 6篇 |
2010年 | 1篇 |
2009年 | 2篇 |
2008年 | 1篇 |
2007年 | 5篇 |
2005年 | 8篇 |
2004年 | 2篇 |
2003年 | 2篇 |
2002年 | 2篇 |
2001年 | 1篇 |
1999年 | 1篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 2篇 |
1979年 | 1篇 |
1977年 | 1篇 |
排序方式: 共有57条查询结果,搜索用时 15 毫秒
1.
Stringer WW Whipp BJ Wasserman K Pórszász J Christenson P French WJ 《European journal of applied physiology》2005,93(5-6):634-639
Published literature asserts that cardiac output (=O2×1/C(a-v)O2) increases as a linear function of oxygen uptake with a slope of approximately 5–6 during constant work rate exercise. However, we have previously demonstrated that C(a-v)O2 has a linear relationship as a function of O2 during progressively increasing work rate incremental exercise. Therefore, we hypothesized that may indeed have a non-linear relationship with respect to O2 during incremental, non-steady state exercise. To investigate this hypothesis, we performed five maximal progressive work rate exercise studies in healthy human subjects. was determined every minute during exercise using measured breath-by-breath O2, and arterial and pulmonary artery measurements of PO2, hemoglobin saturation, and content. was plotted as a function of O2 and the linear and non-linear (first order exponential and hyperbolic) fits determined for each subject. Tests for linearity were performed by assessing the significance of the quadratic terms added to the linear relation using least squares estimation in linear regression. Linearity was inadequate in all cases (group P<0.0001). We conclude that cardiac output is a non-linear function of O2 during ramp-incremental exercise; the pattern of non-linearity suggests that while the kinetics of are faster than those of O2 they progressively slow as work rate (and O2) increases. 相似文献
2.
《European journal of cancer (Oxford, England : 1990)》2015,51(18):2808-2819
BackgroundCancer incidence increases exponentially with advancing age, cancer patients live longer than in the past, and many new treatments focus on stabilizing disease and HRQOL. The objective of this study is to examine how cancer affects patients' HRQOL and whether their HRQOL is age-dependent.MethodsData from 25 EORTC randomized controlled trials was pooled. EORTC QLQ-C30 mean scores for the cancer cohort and five general population cohorts were compared to assess the impact of cancer on patients' HRQOL. Within the cancer cohort, multiple linear regressions (two-sided level P-value = 0.05 adjusted for multiple testing.) were used to investigate the association between age and HRQOL, adjusted for gender, WHO performance status (PS), distant metastasis and stratified by cancer site. A difference of 10 points on the 0–100 scale was considered clinically important.ResultsCancer patients generally have worse HRQOL compared to the general population, but the specific HRQOL domains impaired vary with age. When comparing the cancer versus the general population, young cancer patients had worse financial problems, social and role functioning, while the older cancer groups had more appetite loss. Within the cancer cohort, HRQOL was worse with increasing age for physical functioning and constipation, and better with increasing age for social functioning, insomnia and financial problems (all p < 0.05).ConclusionHRQOL is impaired in cancer patients compared to the general population, but the impact on specific HRQOL domains varies by age. Within the cancer population, some HRQOL components improve with age while others deteriorate. Optimal care for older cancer patients should target HRQOL domains most relevant to this population. 相似文献
3.
早产儿、低出生体重儿喂养方式与体重增长关系的探讨 总被引:17,自引:0,他引:17
目的探讨早产儿、低出生体重儿喂养方式与体重增长关系。方法选择 98例早产儿 ,分成三组 ,一组采用静脉内营养 ,其余两组在消化道喂养同等条件下 ,对其中一组采取头高脚低 (成 2 0°角 )斜坡位。结果观察组与对照组比较体重增长有明显差异 (P <0 .0 5) ;消化道喂养组与静脉内营养组比较体重增长无明显差异 (P >0 .0 5)。结论通过对早产儿及低出生体重儿喂养方式的改进 ,配合全面的综合护理 ,可防止生理性体重下降和维持正常体重的增长。 相似文献
4.
本文分析了最近10多年来国内外针药结合临床循证证据和作用机制研究新进展,认为证据表明针药结合在重大疾病、药源性疾病方面的实践及研究产生的高质量证据进一步证明了其潜在的重要临床价值;针药结合的机制研究已经从关注针灸对药物作用过程的影响向针药不同机制协同作用方向发展。论文针对针药结合规律研究的内容及存在问题分析,提出了针药结合及其研究的四项基本原则,即针药结合增效原则、协同原则、量效原则、时空原则,以期为本领域的发展提供思路。 相似文献
5.
6.
西洋参喷施ABT生根粉增产试验 总被引:2,自引:0,他引:2
西洋参喷施ABT生根粉能够促进生长发育,茎高、茎粗、叶长、叶宽都有明显增长,且减少发病率,叶绿素含量提高2.27%。参根单产提高31.51%。 相似文献
7.
ObjectiveTo investigate the influence of increasing the occlusal vertical dimension (iOVD) on the fibre-type distribution and ultrastructure of deep masseter of rat at different ages.DesignA total of forty-eight male Wistar rats were divided into two groups according to age: ‘teenage’ group (n = 24, 1.5 months) and ‘young adult’ group (n = 24, 8 months). Both the teenage and the young adult rats were then randomly divided into the control group (n = 12) and the experimental group (n = 12). The occlusal vertical dimensions of the rats in the experimental groups were increased by placing composite resin on all maxillary molars. The fibre-type distribution and ultrastructure of the deep masseter were subsequently observed on day 7 and day 14 after iOVD.ResultsIn the teenage experimental group, the proportion of type IIa fibres increased, while the proportion of type IIb and type IIx fibres decreased by day 7 after iOVD (P < 0.05). However, no significant fibre phenotype transformation was observed in the young adult experimental group until day 14 after iOVD. In addition, the proportion of type IIa in the teenage experimental group was higher than that of the young adult experimental group on day 7 and 14 (P < 0.05). Under the transmission electron microscope, muscle fibre reconstruction and the compensatory increase in the number and volume of mitochondria appeared earlier in the teenage experimental group. The cellular traumatic reaction was less than that in the young adult experimental group.ConclusionThe teenage rat alters masseter muscle structure to a slower phenotype earlier and to a greater degree than that of the young adult rat when increasing the occlusal vertical dimension. 相似文献
8.
刘向阳 《中国医疗器械信息》2007,13(8):54-56,59
本文介绍了我国医疗器械行业良好的增长形势,展示了我国医疗器械广阔的市场机遇,指出了国产医疗器械存在的竞争压力。 相似文献
9.
目的监测我院2001—2010年与腹泻有关的耐三代头孢菌素肠道病原菌的增长趋势和耐药谱。为本地区的流行病学研究及临床合理用药提供依据。方法通过大便标本培养,致病菌经生化及血清学进一步鉴定到种或群.并以纸片扩散法测定抗菌药物的敏感性。采用WHONET5.3软件对药敏结果进行统计和分析。结果10年分离出219株耐三代头孢菌素的腹泻病原菌,占同期整个肠道致病菌的9.91%,包括沙门菌9株(4.11%)、志贺菌120株(54.79%)、气单胞菌20株(9.13%)、类志贺毗邻单胞菌2株(0.91%)、致泻大肠埃希菌40株(18.26%)及弧菌28株(12.79%),检出率由2001年的1.5%上升至2010年的近30.0%。219株耐三代头孢菌素病原菌对广谱青霉素和复方新诺明的耐药率均在85.0%以上.对头孢吡肟、头孢美唑、氟喹诺酮类、氯霉素的耐药率在20.0%~36.5%,对磷霉素的耐药率最低(6.7%)。福氏志贺菌、致泻大肠埃希菌、气单胞菌和弧菌对氟喹诺酮类的耐药率明显高于宋内志贺菌;气单胞菌和弧菌对头孢美唑的耐药率高于福氏志贺菌、致泻大肠埃希菌和宋内志贺菌;气单胞菌对磷霉素的耐药率显著高于其他致病菌。结论耐三代头孢菌素的肠道病原菌上升迅速,耐药广泛,不同种属的耐药性不同,应重视监测,加强防治。 相似文献
10.