全文获取类型
收费全文 | 31878篇 |
免费 | 1637篇 |
国内免费 | 501篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 894篇 |
妇产科学 | 219篇 |
基础医学 | 3192篇 |
口腔科学 | 42篇 |
临床医学 | 4052篇 |
内科学 | 11892篇 |
皮肤病学 | 43篇 |
神经病学 | 715篇 |
特种医学 | 1220篇 |
外国民族医学 | 1篇 |
外科学 | 3389篇 |
综合类 | 4068篇 |
现状与发展 | 1篇 |
预防医学 | 1134篇 |
眼科学 | 21篇 |
药学 | 2153篇 |
16篇 | |
中国医学 | 760篇 |
肿瘤学 | 190篇 |
出版年
2023年 | 423篇 |
2022年 | 777篇 |
2021年 | 1007篇 |
2020年 | 915篇 |
2019年 | 1122篇 |
2018年 | 1142篇 |
2017年 | 814篇 |
2016年 | 824篇 |
2015年 | 958篇 |
2014年 | 2183篇 |
2013年 | 1936篇 |
2012年 | 1594篇 |
2011年 | 2023篇 |
2010年 | 1640篇 |
2009年 | 1670篇 |
2008年 | 1753篇 |
2007年 | 1492篇 |
2006年 | 1481篇 |
2005年 | 1321篇 |
2004年 | 1005篇 |
2003年 | 869篇 |
2002年 | 675篇 |
2001年 | 633篇 |
2000年 | 579篇 |
1999年 | 442篇 |
1998年 | 355篇 |
1997年 | 362篇 |
1996年 | 298篇 |
1995年 | 301篇 |
1994年 | 248篇 |
1993年 | 233篇 |
1992年 | 238篇 |
1991年 | 192篇 |
1990年 | 152篇 |
1989年 | 150篇 |
1988年 | 159篇 |
1987年 | 127篇 |
1986年 | 103篇 |
1985年 | 154篇 |
1984年 | 152篇 |
1983年 | 124篇 |
1982年 | 151篇 |
1981年 | 136篇 |
1980年 | 173篇 |
1979年 | 118篇 |
1978年 | 110篇 |
1977年 | 106篇 |
1976年 | 102篇 |
1975年 | 108篇 |
1973年 | 86篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
Paul J. Devlin Brian W. McCrindle James K. Kirklin Eugene H. Blackstone William M. DeCampli Christopher A. Caldarone Ali Dodge-Khatami Pirooz Eghtesady James M. Meza Peter J. Gruber Kristine J. Guleserian Bahaaladin Alsoufi Linda M. Lambert James E. OBrien Erle H. Austin Jeffrey P. Jacobs Tara Karamlou 《The Journal of thoracic and cardiovascular surgery》2019,157(2):684-695.e8
Objective
Arch obstruction after the Norwood procedure is common and contributes to mortality. We determined the prevalence, associated factors, and practice variability of arch reintervention and assessed whether arch reintervention is associated with mortality.Methods
From 2005 to 2017, 593 neonates in the Congenital Heart Surgeons' Society Critical Left Heart Obstruction cohort underwent a Norwood procedure. Median follow-up was 3.7 years. Multivariable parametric models, including a modulated renewal analysis, were performed.Results
Of the 593 neonates, 146 (25%) underwent 218 reinterventions for arch obstruction after the Norwood procedure: catheter-based (n = 168) or surgical (n = 50) at a median age of 4.3 months (quartile 1-quartile 3, 2.6-5.7). Interdigitation of the distal aortic anastomosis was protective against arch reintervention. Development of ≥ moderate tricuspid valve regurgitation and right ventricular dysfunction at any point was associated with arch reintervention. Nonsignificant variables for arch reintervention included shunt type and preoperative aortic measurements. Surgical arch reintervention was protective against arch reintervention, but transcatheter reintervention was associated with increased reintervention. Arch reintervention was not associated with increased mortality. There was wide institutional variation in incidence of arch reintervention (range, 0-40 reinterventions per 100 years patient follow-up) and in preintervention gradient (range, 0-64 mm Hg).Conclusions
Interdigitation of the distal aortic anastomosis during the Norwood procedure decreased the risk of arch reintervention. Surgical arch reintervention is more definitive than transcatheter. Arch reintervention after the Norwood procedure is not associated with increased mortality. Serial surveillance for arch obstruction, integrated with changes in right ventricular function and tricuspid valve regurgitation, is recommended after the Norwood procedure to improve outcomes. 相似文献7.
8.
《Nefrología : publicación oficial de la Sociedad Espa?ola Nefrologia》2022,42(2):145-162
Renal sodium and water retention with resulting extracellular volume expansion and redistribution are hallmark features of heart failure syndromes. However, congestion assessment, monitoring, and treatment represent a real challenge in daily clinical practice. This document reviewed historical and contemporary evidence of available methods for determining volume status and discuss pharmacological aspects and pathophysiological principles that underlie diuretic use. 相似文献
9.
10.
《Nutrition, metabolism, and cardiovascular diseases : NMCD》2022,32(10):2338-2347
Background and aimsResting heart rate variability (HRV) and maximal fat oxidation (MFO) during exercise are both considered as a noninvasive biomarkers for early detection of cardiovascular risk factors. Thus, this study aimed to analyze the relationship between resting HRV parameters and MFO during exercise, and the intensity of exercise that elicit MFO (Fatmax) in healthy sedentary adults.Methods and resultsA total of 103 healthy young adults (22.2 ± 2.3 years old, 67% female; from the ACTIBATE cohort) and 67 healthy middle-aged adults (53.1 ± 5.0 years old, 52% female; from the FIT-AGEING cohort) were included in this cross-sectional study. HRV was assessed using a Polar RS800CX heart rate monitor, while MFO and Fatmax were determined during a graded exercise treadmill test using indirect calorimetry. No significant associations were observed for healthy young adults (standardized β coefficients ranged from ?0.063 to 0.094, and all P ≥ 0.347) and for middle-aged adults (standardized β coefficients ranged from ?0.234 to 0.090, and all P ≥ 0.056). Nevertheless, only a weak association was observed between one HRV parameter in time-domain (the percentage of R-R intervals that shows a difference higher than 50 ms [pNN50]) and MFO in the cohort of middle-aged adults (β coefficient = ?0.279, and P = 0.033).ConclusionThe results of this study suggest that resting HRV parameters are not associated with MFO and Fatmax during exercise in two independent cohorts of healthy sedentary young and middle-aged adults, respectively. 相似文献