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免疫荧光技术在口腔扁平苔藓和慢性盘状红斑狼疮诊断中的价值 总被引:1,自引:0,他引:1
采用免疫荧光技术对口腔扁平苔藓(OLP)和慢性盘状红斑狼疮(DLE)的免疫病理学进行了研究,结果表明,IgG和纤维蛋白原荧光抗体在上皮基底膜区沉积的阳性率两病之间有显著性差异;而胶样小体中出现的阳性率无显著性差异;两病患者的血清抗核抗体阳性率之间亦无显著性差异。 相似文献
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用葡聚糖-活性碳吸附法(DCC法)对87例卵巢恶性肿瘤的雌激素受体(ER)及孕激素受体(PR)进行了测定。ER、PR的阳性率分别为50.6%和58.6%。在不同组织类型中,宫内膜样癌的ER与PR高于其它癌。PR与临床分期呈负相关。多因素分析显示ER、PR均阳性者预后好。ER与PR的测定有助于了解病人预后,对卵巢癌的内分泌治疗有一定指导作用。 相似文献
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观察50例长期配戴亲水性角膜接触镜者戴镜前后SchirmerI试验和泪膜破裂时间(BUT)的变化。结果表明,戴接触镜后BUT缩短,SchirmerI下降,双眼BUT与SchirmerI之间无相关性。讨论了引起泪膜流动和BUT改变的机制。 相似文献
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Barbara S. Ducatman Helen H. Wang Jon G. Jonasson Christine L. Hogan Donald A. Antonioli Gladwyn Leiman 《Diagnostic cytopathology》1993,9(1):98-105
Tubal metaplasia of the endocervix (TME), a condition that may be con/used morphologically with glandular neoplasia, is frequently found in cone or hysterectomy specimens. To determine the frequency of detecting TME in cytologic smears, we retrospectively reviewed 28 Papanicolaou (Pap) smears from 22 women (mean age 39.1 yr; range 25-60 yr) with histologically proven TME. Our criteria for TME were the presence of two cell types in addition to endocervical secretory cells, i.e., peg cells (cells with dark and granular cytoplasm and elongate nuclei) and ciliated cells. All women had cervical cytology specimens obtained with an endocervical brush shortly before the procedures in which TME was diagnosed, and five also had at least one post-procedure smear. Of 20 smears with an adequate, non-neoplastic endocervical component, TME was found in 2 (10%). In these two, TME cells constituted 10% and < 5% of all the glandular cells, respectively, and the percentage of ciliated cells in the TME was approximately 25% and 75%. In conclusion, TME was noted infrequently (10%) on the cervical cytosmears of women with histologically-proven TME. This result corresponds to the histologic finding that TME typically involves the upper endocervix and glandular epithelium, with only 13% of the women having TME on the surface of the lower endocervix. Atypical glandular cells on cervical cytology are a problem for clinicians and pathologists alike. The differential diagnosis of such atypia, including TME, cells of the lower uterine segment, squamous intraepithelial lesion in glands and glandular neoplasia, is discussed. 相似文献
6.
Toshio Morohoshi Fumiaki Sagawa Toshiyuki Mitsuya 《Virchows Archiv : an international journal of pathology》1990,416(3):265-270
Summary The autopsy findings in a pancreatoblastoma in a 7-year-old Japanese girl is reported. The tumour was in the head and body of the pancreas, and was associated with diffuse carcinomatous peritonitis and hepatic and pulmonary metastases. There was marked elevation (more than 10000 ng/ml) of serum alpha-fetoprotein (AFP). Histopathologically the tumour was composed of solid epithelial elements with fibrous stroma, showing acinar arrangement, squamoid clusters and tubular structures. The epithelial elements contained numerous fine PAS positive granules in the cytoplasm. Immunocytochemical results suggested epithelial differentiation with positivity to alpha-1-antitrypsin (AAT), keratin, CA19-9, and AFP. No endocrine elements were recognized. Characteristic feature of this tumour are discussed and compared with prevoius reports. 相似文献
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《Clinical gastroenterology and hepatology》2022,20(12):2728-2740.e1
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Glandular differentiation is exceedingly rare in peripheral nerve sheath tumors. In this report, an exceptional case of retroperitoneal glandular schwannoma is described in which the glandular element is markedly atypical, whereas the schwannian component is benign by morphologic analysis. To the best of our knowledge, the biologic behavior for such a lesion is unknown because similar cases have not yet been described in the literature. 相似文献