全文获取类型
收费全文 | 27739篇 |
免费 | 1691篇 |
国内免费 | 465篇 |
专业分类
耳鼻咽喉 | 168篇 |
儿科学 | 325篇 |
妇产科学 | 346篇 |
基础医学 | 1943篇 |
口腔科学 | 784篇 |
临床医学 | 2695篇 |
内科学 | 2509篇 |
皮肤病学 | 809篇 |
神经病学 | 1344篇 |
特种医学 | 582篇 |
外国民族医学 | 2篇 |
外科学 | 5952篇 |
综合类 | 5804篇 |
现状与发展 | 1篇 |
预防医学 | 2090篇 |
眼科学 | 957篇 |
药学 | 2519篇 |
50篇 | |
中国医学 | 595篇 |
肿瘤学 | 420篇 |
出版年
2023年 | 497篇 |
2022年 | 753篇 |
2021年 | 1105篇 |
2020年 | 1050篇 |
2019年 | 1337篇 |
2018年 | 1196篇 |
2017年 | 1010篇 |
2016年 | 818篇 |
2015年 | 875篇 |
2014年 | 1833篇 |
2013年 | 1770篇 |
2012年 | 1703篇 |
2011年 | 1727篇 |
2010年 | 1379篇 |
2009年 | 1261篇 |
2008年 | 1160篇 |
2007年 | 1171篇 |
2006年 | 1048篇 |
2005年 | 959篇 |
2004年 | 661篇 |
2003年 | 575篇 |
2002年 | 513篇 |
2001年 | 437篇 |
2000年 | 339篇 |
1999年 | 297篇 |
1998年 | 270篇 |
1997年 | 249篇 |
1996年 | 201篇 |
1995年 | 210篇 |
1994年 | 180篇 |
1993年 | 152篇 |
1992年 | 126篇 |
1991年 | 150篇 |
1990年 | 128篇 |
1989年 | 107篇 |
1988年 | 121篇 |
1987年 | 117篇 |
1985年 | 229篇 |
1984年 | 298篇 |
1983年 | 199篇 |
1982年 | 220篇 |
1981年 | 193篇 |
1980年 | 183篇 |
1979年 | 162篇 |
1978年 | 135篇 |
1977年 | 112篇 |
1976年 | 153篇 |
1975年 | 115篇 |
1974年 | 112篇 |
1973年 | 120篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Provocation of Atrial Fibrillation Triggers During Ablation: Does the Use of General Anesthesia Affect Inducibility?
下载免费PDF全文
![点击此处可从《Journal of cardiovascular electrophysiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
5.
Anatoly E Martynyuk Ling-Sha Ju Timothy E Morey Jia-Qiang Zhang 《World Journal of Psychiatry》2020,10(5):81-94
The progress of modern medicine would be impossible without the use of general anesthetics (GAs). Despite advancements in refining anesthesia approaches, the effects of GAs are not fully reversible upon GA withdrawal. Neurocognitive deficiencies attributed to GA exposure may persist in neonates or endure for weeks to years in the elderly. Human studies on the mechanisms of the long-term adverse effects of GAs are needed to improve the safety of general anesthesia but they are hampered not only by ethical limitations specific to human research, but also by a lack of specific biological markers that can be used in human studies to safely and objectively study such effects. The latter can primarily be attributed to an insufficient understanding of the full range of the biological effects induced by GAs and the molecular mechanisms mediating such effects even in rodents, which are far more extensively studied than any other species. Our most recent experimental findings in rodents suggest that GAs may adversely affect many more people than is currently anticipated. Specifically, we have shown that anesthesia with the commonly used GA sevoflurane induces in exposed animals not only neuroendocrine abnormalities (somatic effects), but also epigenetic reprogramming of germ cells (germ cell effects). The latter may pass the neurobehavioral effects of parental sevoflurane exposure to the offspring, who may be affected even at levels of anesthesia that are not harmful to the exposed parents. The large number of patients who require general anesthesia, the even larger number of their future unexposed offspring whose health may be affected, and a growing number of neurodevelopmental disorders of unknown etiology underscore the translational importance of investigating the intergenerational effects of GAs. In this mini review, we discuss emerging experimental findings on neuroendocrine, epigenetic, and intergenerational effects of GAs. 相似文献
6.
F. Giovanardi F. Nudo Q. Lai M. Garofalo A. Consolo E. Choppin De Janvry G.A. Arroyo Murillo P. Ursi D. Stabile F. Melandro P.B. Berloco R. Pretagostini L. Poli 《Transplantation proceedings》2019,51(1):128-131
Background
Arterial vascular anomalies in patients undergoing kidney transplantation (KT) are correlated with a higher incidence of early surgical complications, potentially causing graft loss. Arterial reconstruction allows patients to overcome these surgical challenges, thus minimizing the risk of poor outcomes. The aim of the present study is to retrospectively investigate the safety and effectiveness of the multiple arterial reconstruction technique with a Teflon patch in case of an unavailable aortic patch: to do so, surgical complications, graft function, and patient survival were evaluated.Methods
During the period January 2009 to August 2016, 202 adult deceased-donor KTs were performed at our center. Group A (n = 27; reconstruction of multiple arteries) and Group B (n = 175; control group) were compared.Results
No differences were observed between the 2 groups in terms of early postoperative course, with no vascular complication observed in Group A. No vascular patch infections were reported, nor longer cold ischemia time rates. Similarly, long-term survival rates were similar between the 2 groups.Conclusions
The Teflon-patch arterial reconstruction technique appears to be safe and effective, with an acceptable balance of benefits and potential risks of using a prosthetic material. Studies based on larger series are needed to further validate this approach. 相似文献7.
8.
Platelet function has been described by many laboratory assays, and PL-11 is a new point-of-care platelet function analyzer based on platelet count drop method, which counts platelet before and after the addition of agonists in the citrated whole blood samples. The present study sought to compare PL-11 with other three major more established assays, light transmission aggregometry (LTA), VerifyNow? aspirin system and thromboelastography (TEG), for monitoring the short-term aspirin responses in healthy individuals. Ten healthy young men took 100?mg/d aspirin for 3-day treatment. Platelet function was measured via PL-11, LTA, VerifyNow and TEG, respectively. The blood samples were collected at baseline, 2 hour, 1 day during the aspirin treatment and 1 day, 5?±?1 days, 8?±?1 days after the aspirin withdrawal. Moreover, 90 additional healthy subjects were recruited to establish a reference range for PL-11. Platelet function of healthy subjects decreased significantly 2 hours after 100?mg/d aspirin intake and began to recover during 4–6 days after the aspirin withdrawal. Correlations between methods were PL-11 vs. LTA (r?=?0.614, p?<?0.01); PL-11 vs. VerifyNow (r?=?0.829, p?<?0.01); PL-11 vs. TEG (r?=?0.697, p?<?0.001). There was no significant bias between PL-11 and LTA at baseline (bias?=?1.94%, p?=?0.804) using Bland-Altman analysis, while the data of PL-11 were significantly higher than LTA (bias?=?24.02%, p?<?0.001) during the aspirin therapy. The reference range for PL-11 in healthy young individuals was from 66.8 to 90.5% (95%CI). When aspirin low-responsiveness was defined as LTA?>?20%, the cut-off values for each method were, respectively: PL-11?>?50%, VerifyNow?>?533 ARU, TEG?>?60.2%. The results of different platelet function assays were uninterchangeable for monitoring aspirin response and correlations among them were also varied. Correlations among PL-11 and other three major assays suggested the ability of PL-11 to assess the treatment effects of aspirin. But a large cohort study is needed to confirm the cut-off value of aspirin response detected by PL-11. 相似文献
9.
10.
《Bulletin du cancer》2019,106(4):389-394