A new steroidal saponin from dragon's blood of Dracaena cambodiana

Phytochemical study on dragon's blood of Dracaena cambodiana led to a new steroidal saponin, cambodianoside G (1), and six known ones (2–7). The structure of the new compound was elucidated on the basis of detailed spectroscopic analysis. Evaluation of antibacterial activities showed that compound 7 exhibited antibacterial activity against Staphylococcus aureus.     

A new cytotoxic homoisoflavonoid from Dracaena cambodiana

A new homoisoflavonoid, named cambodianol (1), together with the two known flavanes, (2S)-7,3′-dihydroxy-4′-methoxy-8-methylflavane (2) and (2R)-7,4′-dihydroxy-8-methylflavane (3), were isolated from the stems of Dracaena cambodiana. Their structures were determined based on HR-ESI-MS and spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 1 exhibited significant cytotoxic activities against K562 and SGC-7901 with the IC₅₀ values of 1.4 and 2.9 μg/ml, respectively.     

Pregnane glycosides from Dracaena cochinchinensis

Two new pregnane glycosides, named dracaenoside C and D, were isolated from the fresh stems of Dracaena cochinchinensis. Their structures were established as 3β,14α-dihydroxypregna-5,16(17)-diene-20-one?3-O-α-L-rhamnopyranosyl(1→2)[α-L-rhamnopyranosyl(1→4)]-β-D-glucopyranoside (1) and 3β,14α-dihydroxypregna-5,16(17)-diene-20-one?3-O-α-L-rhamnopyranosyl(1→2)[β-D-glucopyranosyl(1→3)]-β-D-glucopyranoside (2) by means of 2D NMR spectral and chemical methods.     

A new meta-homoisoflavane from the fresh stems of dracaena cochinchinensis

A new meta-homoisoflavane, 10,11-dihydroxydracaenone C (1), together with 7,4′-dihydroxyflavone (2), 7,4′-dihydroxyflavane (3), 4,4′-dihydroxy-2-methoxychalcone (4), 4,4′-dihydroxy-2-methoxydihydrochalcone (5), 7,4′-dihydrohomoisoflavanone (6), 7,4′-homoisoflavane (7), lophenol (8), β-sitosterol (9), stigma-5, 22-diene-3-ol (10), 1-(4′-O-β-d-glucopyranosyl)benzyl-ethan-2-ol (11), 3,4-dihydoxy-1-allylbenezene-4-O-α-l-rhamnopyranosyl-(1 → 6)-O-β-d-glucopyranoside (12), 1-hydroxy-3,4,5-trimethoxybenzene-1-O-α-l-apiopyranosyl-(1 → 6)-O-β-d-glucopyranoside (13), and tachioside (14) have been isolated from the fresh stems of Dracaena cochinchinensis. Their structures have been established by spectroscopic analysis, especially by 2D NMR. This is the first time compounds 11, 13, 14 have been isolated from Dracaena.     

国产血竭的化学成分研究

目的 研究国产商品血竭的活性成分。方法 用甲醇提取,Sephadex LH-20、MCIgel和硅胶柱色谱分离国产商品血竭中的化学成分,用现代波谱方法进行结构鉴定。结果 从国产雨林牌血竭的甲醇浸提物中分离并鉴定了12个化合物,它们分别为：26-O-β-D-葡萄吡喃糖基-呋甾烷-5,25(27)-二烯-1β,3β,22β,26-四醇-1-O-a-L-阿拉伯吡喃糖苷(1),3,4-二羟基烯丙基苯-4-O-β-D-葡萄吡喃糖苷(Ⅱ),7-羟基-3-(对-羟基苯基)-色原烷(Ⅲ),7,4’-二羟基-3’一甲氧基黄烷(Ⅳ),3,4-二羟基烯丙基苯(Ⅴ),白藜芦醇(Ⅵ),7,4’-二羟基二氢黄酮(Ⅶ),二对羟基苯基甲烷(Ⅶ),五加苷B(Ⅸ),对羟基苯甲酸(X),对羟基苯酚(Ⅺ)和原儿茶醛(Ⅻ)。结论 化合物1为一新的甾体配糖体,Ⅱ为一新酚苷,Ⅴ～Ⅻ为首次从该植物中分得．     

国产血竭的化学成分研究

目的 研究国产商品血竭的活性成分。方法 用甲醇提取,Sephadex LH-20、MCIgel和硅胶柱色谱分离国产商品血竭中的化学成分,用现代波谱方法进行结构鉴定。结果 从国产雨林牌血竭的甲醇浸提物中分离并鉴定了12个化合物,它们分别为：26-O-β-D-葡萄吡喃糖基-呋甾烷-5,25(27)-二烯-1β,3β,22β,26-四醇-1-O-a-L-阿拉伯吡喃糖苷(1),3,4-二羟基烯丙基苯-4-O-β-D-葡萄吡喃糖苷(Ⅱ),7-羟基-3-(对-羟基苯基)-色原烷(Ⅲ),7,4’-二羟基-3’一甲氧基黄烷(Ⅳ),3,4-二羟基烯丙基苯(Ⅴ),白藜芦醇(Ⅵ),7,4’-二羟基二氢黄酮(Ⅶ),二对羟基苯基甲烷(Ⅶ),五加苷B(Ⅸ),对羟基苯甲酸(X),对羟基苯酚(Ⅺ)和原儿茶醛(Ⅻ)。结论 化合物1为一新的甾体配糖体,Ⅱ为一新酚苷,Ⅴ～Ⅻ为首次从该植物中分得．