全文获取类型
收费全文 | 23491篇 |
免费 | 1671篇 |
国内免费 | 447篇 |
专业分类
耳鼻咽喉 | 111篇 |
儿科学 | 522篇 |
妇产科学 | 553篇 |
基础医学 | 3707篇 |
口腔科学 | 489篇 |
临床医学 | 1979篇 |
内科学 | 3050篇 |
皮肤病学 | 294篇 |
神经病学 | 1948篇 |
特种医学 | 1288篇 |
外国民族医学 | 4篇 |
外科学 | 1647篇 |
综合类 | 2548篇 |
现状与发展 | 2篇 |
预防医学 | 1361篇 |
眼科学 | 166篇 |
药学 | 2900篇 |
3篇 | |
中国医学 | 696篇 |
肿瘤学 | 2341篇 |
出版年
2023年 | 247篇 |
2022年 | 504篇 |
2021年 | 612篇 |
2020年 | 586篇 |
2019年 | 697篇 |
2018年 | 707篇 |
2017年 | 692篇 |
2016年 | 734篇 |
2015年 | 775篇 |
2014年 | 1353篇 |
2013年 | 1575篇 |
2012年 | 1208篇 |
2011年 | 1537篇 |
2010年 | 1114篇 |
2009年 | 1138篇 |
2008年 | 1107篇 |
2007年 | 1148篇 |
2006年 | 1046篇 |
2005年 | 949篇 |
2004年 | 849篇 |
2003年 | 707篇 |
2002年 | 577篇 |
2001年 | 549篇 |
2000年 | 478篇 |
1999年 | 399篇 |
1998年 | 342篇 |
1997年 | 336篇 |
1996年 | 274篇 |
1995年 | 278篇 |
1994年 | 258篇 |
1993年 | 223篇 |
1992年 | 178篇 |
1991年 | 161篇 |
1990年 | 188篇 |
1989年 | 120篇 |
1988年 | 122篇 |
1987年 | 125篇 |
1986年 | 116篇 |
1985年 | 188篇 |
1984年 | 241篇 |
1983年 | 130篇 |
1982年 | 165篇 |
1981年 | 150篇 |
1980年 | 121篇 |
1979年 | 107篇 |
1978年 | 80篇 |
1977年 | 67篇 |
1976年 | 77篇 |
1975年 | 66篇 |
1974年 | 75篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
This retrospective study aimed to evaluate radiation-induced pneumonitis (RIP) and a related condition that we define in this report—prolonged minimal RIP (pmRIP)—after stereotactic body radiotherapy (SBRT) for Stage I primary lung cancer in patients with chronic obstructive pulmonary disease (COPD). We assessed 136 Stage I lung cancer patients with COPD who underwent SBRT. Airflow limitation on spirometry was classified into four Global Initiative for Chronic Obstructive Lung Disease (GOLD) grades, with minor modifications: GOLD 1 (mild), GOLD 2 (moderate), GOLD 3 (severe) and GOLD 4 (very severe). On this basis, we defined two subgroups: COPD-free (COPD −) and COPD-positive (COPD +). There was no significant difference in overall survival or cause-specific–survival between these groups. Of the 136 patients, 44 (32%) had pmRIP. Multivariate analysis showed that COPD and the Brinkman index were statistically significant risk factors for the development of pmRIP. COPD and the Brinkman index were predictive factors for pmRIP, although our findings also indicate that SBRT can be tolerated in early lung cancer patients with COPD. 相似文献
4.
《Journal of cranio-maxillo-facial surgery》2020,48(2):170-175
AimThe purpose of this study was to evaluate the efficiency of pyramidal and posterior osseous release (PPOR) for maxillary impaction using an ultrasonic bone-cutting device after Le Fort I (LFI) osteotomy.Materials and methodsIn total, 31 Japanese adults with jaw deformities, diagnosed as having maxillary excess with mandibular prognathism or deficiency, underwent LFI osteotomy and bilateral sagittal split osteotomy. The patients were divided into two groups: a trimming group (15 patients, four men and 11 women; mean age 24.8 years) and a PPOR group (16 patients, seven men and nine women; mean age 22.8 years). In the trimming group, osseous interference around the descending palatine artery (DPA) was removed using forceps, rounding bur, and reciprocating rasp. The PPOR technique was used to remove osseous fragments created by V-shaped osteotomy around the DPA following vertical osteotomy behind the DPA using an ultrasonic bone-cutting device (Variosurg 3; NSK, Tochigi, Japan). The operative times for maxillary osteotomy, total operative times (including bilateral sagittal split osteotomy), and total blood loss were assessed.ResultsThe mean planned amounts of maxillary impaction were 4.37 ± 1.27 mm in the trimming group and 4.38 ± 1.36 mm in the PPOR group (p = 0.98). The mean maxillary operative time for the PPOR group was significantly shorter, by 25.5% (p < 0.001). Total operative time for the PPOR group was also significantly shorter, by 24.3% (p < 0.001). Mean blood loss was significantly lower in the PPOR group than in the trimming group (p = 0.003).ConclusionThe PPOR technique for maxillary impaction after LFI osteotomy shortened the operative time and enabled secure reduction of the maxilla in patients who required the treatment of maxillary impaction with preservation of the DPA bundle. 相似文献
5.
F. Giovanardi F. Nudo Q. Lai M. Garofalo A. Consolo E. Choppin De Janvry G.A. Arroyo Murillo P. Ursi D. Stabile F. Melandro P.B. Berloco R. Pretagostini L. Poli 《Transplantation proceedings》2019,51(1):128-131
Background
Arterial vascular anomalies in patients undergoing kidney transplantation (KT) are correlated with a higher incidence of early surgical complications, potentially causing graft loss. Arterial reconstruction allows patients to overcome these surgical challenges, thus minimizing the risk of poor outcomes. The aim of the present study is to retrospectively investigate the safety and effectiveness of the multiple arterial reconstruction technique with a Teflon patch in case of an unavailable aortic patch: to do so, surgical complications, graft function, and patient survival were evaluated.Methods
During the period January 2009 to August 2016, 202 adult deceased-donor KTs were performed at our center. Group A (n = 27; reconstruction of multiple arteries) and Group B (n = 175; control group) were compared.Results
No differences were observed between the 2 groups in terms of early postoperative course, with no vascular complication observed in Group A. No vascular patch infections were reported, nor longer cold ischemia time rates. Similarly, long-term survival rates were similar between the 2 groups.Conclusions
The Teflon-patch arterial reconstruction technique appears to be safe and effective, with an acceptable balance of benefits and potential risks of using a prosthetic material. Studies based on larger series are needed to further validate this approach. 相似文献6.
《Molecular therapy》2022,30(12):3587-3600
- Download : Download high-res image (165KB)
- Download : Download full-size image
7.
欧洲药品局(EMA)于2018年11月发布了"人用药品辅料右旋糖酐的包装说明书资料",该文件引用大量文献全面评价了右旋糖酐的安全性,特别指出含有右旋糖酐辅料的注射和吸入制剂的疫苗与药品,应在说明书中描述有关其过敏反应信息的新要求。介绍该文件的主要内容,期望对我国这类药品说明书的撰写和监管有所帮助。 相似文献
8.
9.
- Download : Download high-res image (66KB)
- Download : Download full-size image
10.
《Seminars in immunology》2015,27(6):369-378
Macrophages are important for tissue development, homeostasis as well as immune response upon injury or infection. For a long time they were only seen as one uniform group of phagocytes with a common origin and similar functions. However, this view has been challenged in the last decade and revealed a complex diversity of tissue resident macrophages. Here, we want to present the current view on macrophage development and tissue specification and we will discuss differences as well as common patterns between heterogeneous macrophage subpopulations. 相似文献