水稻高,矮秆杂种以矮秆品种复交F1的半矮秆,产量及外观品质...

8个水稻高矮秆杂种以矮秆品种复交组合F_1高矮秆呈1:1分离。控制株高和抽穗日数两对性状是独立遗传的。在矮秆群体中选择半矮秆个体可得到穗数较多、稻穗较大、粒数多的高产个体。单株穗重与有效穗数、主穗粒数;穗粒数与穗长呈极显著正相关。谷米粒长/宽比与垩白率基本上呈负相关。     

剪切修复交叉互补基因对非小细胞肺癌含铂化疗影响的研究进展

肺癌的发病率及死亡率在我国均有逐年上升的趋势。铂类药物是非小细胞肺癌化疗的基础药物,但在化疗方案及给药剂量相同的情况下,不同个体对化疗的敏感性差异很大。这种差异可以用     

Excision repair cross complementation group 1 polymorphisms and lung cancer risk: a meta-analysis

Background  Several studies have evaluated the association between polymorphisms of encoding excision repair cross complementation group 1 (ERCC1) enzyme and lung cancer risk in diverse populations but with conflicting results. By pooling the relatively small samples in each study, it is possible to perform a meta-analysis of the evidence by rigorous methods.

Methods  Embase, Ovid, Medline and Chinese National Knowledge Infrastructure were searched. Additional studies were identified from references in original studies or review articles. Articles meeting the inclusion criteria were reviewed systematically, and the reported data were aggregated using the statistical techniques of meta-analysis.

Results  We found 3810 cases with lung cancer and 4332 controls from seven eligible studies. T19007C polymorphism showed no significant effect on lung cancer risk (C allele vs. T allele: odds ratio (OR)=0.91, 95% confidence interval (CI)=0.80–1.04; CC vs. TT: OR=0.76, 95% CI=0.56–1.02; CC vs. (CT+TT): OR=0.96, 95% CI=0.84–1.10). Similarly, there was no significant main effects for T19007C polymorphism on lung cancer risk when stratified analyses by ethnicity (Chinese or Caucasian). No significant association was found between C8092A polymorphism (3060 patients and 2729 controls) and the risk of lung cancer (A allele vs. C allele: OR=1.03, 95% CI=0.95–1.11; AA vs. CC: OR=1.08, 95% CI=0.88–1.33; AA vs. (AC+CC): OR=1.08, 95% CI=0.88–1.31).

Conclusion  We found little evidence of an association between the T1900C or C8092A polymorphisms of ERCC 1 and the risk of lung cancer in Caucasian or Han Chinese people.