全文获取类型
收费全文 | 1141篇 |
免费 | 99篇 |
国内免费 | 32篇 |
专业分类
儿科学 | 12篇 |
妇产科学 | 26篇 |
基础医学 | 59篇 |
临床医学 | 152篇 |
内科学 | 88篇 |
皮肤病学 | 5篇 |
神经病学 | 3篇 |
特种医学 | 53篇 |
外国民族医学 | 2篇 |
外科学 | 420篇 |
综合类 | 198篇 |
预防医学 | 17篇 |
眼科学 | 1篇 |
药学 | 46篇 |
2篇 | |
中国医学 | 4篇 |
肿瘤学 | 184篇 |
出版年
2023年 | 28篇 |
2022年 | 32篇 |
2021年 | 40篇 |
2020年 | 44篇 |
2019年 | 37篇 |
2018年 | 33篇 |
2017年 | 43篇 |
2016年 | 42篇 |
2015年 | 50篇 |
2014年 | 93篇 |
2013年 | 82篇 |
2012年 | 47篇 |
2011年 | 78篇 |
2010年 | 71篇 |
2009年 | 58篇 |
2008年 | 47篇 |
2007年 | 57篇 |
2006年 | 53篇 |
2005年 | 53篇 |
2004年 | 47篇 |
2003年 | 24篇 |
2002年 | 23篇 |
2001年 | 32篇 |
2000年 | 17篇 |
1999年 | 17篇 |
1998年 | 11篇 |
1997年 | 13篇 |
1996年 | 19篇 |
1995年 | 13篇 |
1994年 | 9篇 |
1993年 | 3篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 6篇 |
1989年 | 2篇 |
1988年 | 8篇 |
1987年 | 3篇 |
1986年 | 6篇 |
1985年 | 4篇 |
1984年 | 8篇 |
1983年 | 3篇 |
1982年 | 3篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
排序方式: 共有1272条查询结果,搜索用时 15 毫秒
1.
分析原发性腹膜后恶性肿瘤12例。83%以腹块和腹痛为主要症状,体征中腹块占91.5%,以恶性淋巴瘤居首位占61%。全组完全切除率为58%,行脏器联合切除占25%。完全切除加放疗、化疗3年存活率为28.5%,部分切除及活检未给其它治疗者5例预后差,均1年内死亡,差别显著。 相似文献
2.
Schwannomas account for only a small percentage of retroperitoneal tumours. Presentation is typically varied and non-specific and pre-operative diagnosis is difficult. Herein are described five cases of retroperitoneal schwannoma. Presentation was varied, ranging from abdominal pain, abdominal mass, obstructed labour or an incidental finding. All patients had either an abdominal computed tomography scan and/or ultrasound performed. Pre-operative biopsy either by fine needle aspiration (in one patient) or core biopsy in two patients was unhelpful. In four patients with smaller tumours, complete excision was possible with no apparent long-term morbidity and no clinical evidence of recurrent tumour with follow up from 3.5 months to 11 years. For the largest tumour, complete surgical excision was not attempted as it would have entailed significant morbidity. 相似文献
3.
YASUMASA SHICHIRI NORIYASU TAKAO TOMOYUKI OIDA HIROSHI KANAMARU YOSUKE SHIMIZU 《International journal of urology》2004,11(11):1019-1023
The most serious problem regarding a laparoscopic partial nephrectomy is how to perform bloodless excision without causing renal ischemia in a limited working space. We report the case of a 65-year-old man with left small renal cell carcinoma in the posterior mid zone who underwent a laparoscopic partial nephrectomy through a retroperitoneal approach by carrying out the ligation of the tumor-feeding artery, but without clamping the renal pedicle. Both preoperative abdominal computed tomography (CT) and intraoperative ultrasonography revealed the tumor to be fully encapsulated. The tumor-feeding artery could be exposed by dissection from the renal hilum and, after an arterial ligation, tumor resection with a safety margin was smoothly performed with minimal bleeding. Postoperatively, CT revealed a limited defect of the renal parenchyma and excretory pyelography showed no urine leakage or urinary tract obstruction. The preoperative and postoperative creatinine levels were 0.66 and 0.69 mg/dL, respectively. As a result, a tumor-feeding artery ligation with a laparoscopic partial nephrectomy for left renal cell carcinoma in the posterior mid zone is considered to be an effective surgical modality which avoids renal ischemia and pelvic heat injury. 相似文献
4.
Retroperitoneal cystic lymphangioma is a rare congenital malformation. The majority of lymphangiomas are present at birth and nearly all present before the age of two years. We report a case of giant cystic retroperitoneal lymphangioma in a patient who first presented with symptoms at the age of 7, underwent surgery, and who then suffered a recurrent mass 11 years later. 相似文献
5.
目的通过动物实验评价心腔内导管超声探头对部分腹膜后脏器结构的显像效果,以及其用于腹膜后脏器显像的可行性。方法静脉鞘管引导心腔内导管超声探头进入下腔静脉,通过对8只实验犬部分腹膜后脏器的近距离超声成像,记录成像过程动物生理参数,观察其二维图像及彩色血流显像效果,并与常规经腹超声检查效果比较。结果实验前与腔内显像过程中犬的心率、动脉压、呼吸频率差异无统计学意义(P〉0.05);心腔内导管超声可清晰显示肾脏、肾上腺、大血管旁淋巴结等腹膜后脏器的二维细微结构及彩色血流分布,成像质量明显优于经腹切面的显示效果。结论采用心腔内导管超声观察腹膜后部分脏器的结构是安全可行的,成像质量明显优于经腹切面的显示效果,对肾上腺及其血供的显像尤为清晰。心腔内导管超声在腹膜后脏器显像方面有重要应用价值,为腹膜后脏器的超声检查提供了一种新方法。 相似文献
6.
Laparoscopy and major retroperitoneal vascular injuries (MRVI) 总被引:2,自引:0,他引:2
Injury to major retroperitoneal vessels is a potential serious complication of laparoscopy occurring when the Veress needle or trocar is inserted. This report is a review of major retropertioneal vascular injuries (MRVI) occurring during laparoscopy, as these injuries have not been well documented in the literature. A retrospective, observational review of general surgical laparoscopy cases was conducted over a 3.5-year period in three community, university-affiliated hospitals. We identified 4 MRVI in 3591 laparoscopic procedures. These cases were critically analyzed and compared. The incidence of MRVI was 0.1%. All cases occurred with the closed (blind) insertion technique of Veress needle and primary trocar insertion technique with disposable safety shield trocars. All patients sustaining MRVI had acute hypotension introperatively and significant blood loss necessitating postoperative transfusions. Recognition and rapid conversion to laparotomy are keys to enhancing outcome. There is significant potential for morbidity and mortality with laparoscopic MRVI, although each patient in this series was discharged without obvious short-term problems. The advantages of an open approach for primary trocar insertion are numerous and should alleviate the risk of MRVI associated with general laparoscopic surgery.Presented at the annual meeting of the Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Orlando, FL, USA, 11–14 March 1995; and the Third European Congress of the European Association for Endoscopic Surgery, Luxembourg, 13–17 June 1995 相似文献
7.
目的:探讨CT对原发性腹膜后肿瘤的诊断价值。方法:搜集7例经手术病理确诊的原发性腹膜后肿瘤的病例,分析其影像表现,6例行平扫及增强检查,一例仅行平扫检查。结果:脂肪肉瘤1例、平滑肌肉瘤1例、纤维肉瘤1例、畸胎瘤2例、神经母细胞瘤2例。结论:掌握腹膜后区的正常解剖结构,能提高对肿瘤定位诊断的准确性,同时结合肿瘤的CT表现及临床资料等,对肿瘤的定性诊断有一定帮助。 相似文献
8.
Primary retroperitoneal perirenal CIC rearrangement sarcoma is rare. The current case report presents a 69-year-old male patient with this pathology, including the clinical features, pathomorphology and immunohistochemistry, and CIC gene rupture detected by fluorescence in situ hybridization (FISH). Furthermore, the relevant literature was reviewed. Histologically, the tumor was composed of diffuse nests of small- to medium-sized juvenile round blue cells with hyperchromatic nuclei, prominent nucleoli and occasional mitotic signs. The tumor involved adipose tissue with no obvious hemorrhagic necrotic foci. Immunohistochemistry indicated scattered expression of CD99 in tumor cells. FISH examination suggested that the CIC gene was fragmented and translocated. 相似文献
9.
目的探讨CT和MRI诊断特发性腹膜后纤维化的临床特点。方法选取2010年1月~2012年1月我院收治的特发性腹膜后纤维化患者18例进行回顾性分析。结果特发性腹膜后纤维化临床表现为非特异性腹痛、背痛、下肢浮肿、消瘦乏力等;CT表现为腹膜后不规则软组织密度影,有纤维性斑或异常软组织包块;MRI检查发现患者腹膜后硬化斑块、脂肪组织和肌肉组织在T1和T2图像中的密度不同:经CT和MRI诊断患者呈现出不同的影像学分期。结论特发性腹膜后纤维化临床表现复杂却不特异.其诊断主要依靠CT和MRI影像学检查。 相似文献
10.
Xianjin Wang Jun Yao Xingwei Jin Xiang Zhang Guoliang Lu Yuan Shao Junwei Pan 《Translational andrology and urology》2022,11(5):607
BackgroundRadical nephroureterectomy (RNU) is the principal method for treatment of high-risk upper urinary tract urothelial carcinoma (UTUC). The transperitoneal approach is associated with poor disease progression, but the distal ureter-bladder cuff (DUBC) resection through retroperitoneal laparoscopic approach is difficult. This study proposed a modulated RNU technique, namely, total retroperitoneal laparoscopic radical nephroureterectomy (tRLRNU), with its advantages of DUBC resection and requiring fewer trocars etc. The efficiency, safety, and short-term impacts were retrospectively compared with total transperitoneal laparoscopic radical nephroureterectomy (tTLRNU).MethodsTotal of 12 patients who received tRLRNU and 28 patients who received tTLRNU were enrolled. The choice of surgical approach was random and their data were retrospectively analyzed. During tRLRNU, the laparoscope was versed towards the caudal direction and a retroperitoneal laparoscopic ureterectomy was performed. The bladder cuff was entirely transected and the bladder incision was sutured. The tRLRNU cases were compared with the tTLRNU cases in terms of general clinical data, pathologic parameters, peri-operative parameters, adjuvant therapy, and short-term outcomes. The independent samples t-tests, chi-square tests, and Fischer exact tests were used to analyze the differences.ResultsThere were no significant differences in the basic patient characteristics between the 2 groups. The data were comparable. There were significantly fewer trocars utilized in tRLRNU group compared to tTLRNU group (P=0.0008). tRLRNU group experienced less blood loss (98.33±61.32 versus 170.71±121.32 mL; P=0.017), smaller drainage volume (182.08±163.60 versus 1,924.82±3,370.02 mL; P=0.011), and shorter extubation time (5.67±1.07 versus 8.57±6.96 days; P=0.040) compared to tRLRNU group. There were no statistically differences in the other peri-operative parameters, including whole operation time, transfusion, visceral and vascular injuries, open conversion, post-operative bleeding, recovery time of intestinal function, and discharge time. The patient outcomes in tTLRNU group at 6 months were significantly worse than that of tRLRNU group by comparing progression-free survival, progression survival and mortality (P=0.039).ConclusionsThe tRLRNU was potentially safer, minimally invasive, and more effective compared to the tTLRNU. Due to the small sample size, short follow-up time and no randomization of the study, future comparative studies are warranted to further analyze long-term outcomes of tRLRNU. 相似文献