全文获取类型
收费全文 | 3475篇 |
免费 | 279篇 |
国内免费 | 106篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 35篇 |
妇产科学 | 5篇 |
基础医学 | 442篇 |
口腔科学 | 31篇 |
临床医学 | 360篇 |
内科学 | 154篇 |
皮肤病学 | 3篇 |
神经病学 | 262篇 |
特种医学 | 282篇 |
外科学 | 1027篇 |
综合类 | 679篇 |
预防医学 | 53篇 |
眼科学 | 3篇 |
药学 | 151篇 |
8篇 | |
中国医学 | 294篇 |
肿瘤学 | 61篇 |
出版年
2024年 | 27篇 |
2023年 | 62篇 |
2022年 | 144篇 |
2021年 | 136篇 |
2020年 | 154篇 |
2019年 | 123篇 |
2018年 | 99篇 |
2017年 | 129篇 |
2016年 | 172篇 |
2015年 | 141篇 |
2014年 | 250篇 |
2013年 | 231篇 |
2012年 | 272篇 |
2011年 | 226篇 |
2010年 | 175篇 |
2009年 | 144篇 |
2008年 | 143篇 |
2007年 | 149篇 |
2006年 | 128篇 |
2005年 | 115篇 |
2004年 | 111篇 |
2003年 | 117篇 |
2002年 | 88篇 |
2001年 | 59篇 |
2000年 | 47篇 |
1999年 | 50篇 |
1998年 | 58篇 |
1997年 | 41篇 |
1996年 | 35篇 |
1995年 | 22篇 |
1994年 | 34篇 |
1993年 | 37篇 |
1992年 | 15篇 |
1991年 | 22篇 |
1990年 | 12篇 |
1989年 | 11篇 |
1988年 | 8篇 |
1987年 | 8篇 |
1986年 | 8篇 |
1985年 | 8篇 |
1984年 | 8篇 |
1983年 | 2篇 |
1982年 | 13篇 |
1981年 | 7篇 |
1980年 | 7篇 |
1979年 | 1篇 |
1977年 | 5篇 |
1976年 | 3篇 |
1974年 | 2篇 |
1971年 | 1篇 |
排序方式: 共有3860条查询结果,搜索用时 15 毫秒
1.
椎动脉型颈椎病的影像学诊断 总被引:2,自引:0,他引:2
本文描述了椎动脉型颈椎病的概念及发病机制 ,并对该病的各种影像学检查的主要表现及优缺点进行了综述。 相似文献
2.
3.
老年性骨质疏松脊柱良性骨折与转移瘤性骨折的MRI鉴别 总被引:13,自引:0,他引:13
目的探讨脊椎骨质疏松性压缩骨折的MRI表现及其与转移性压缩骨折的鉴别诊断.资料与方法回顾性分析53例老年性骨质疏松伴压缩性骨折和20例转移性椎体压缩骨折患者的MRI资料.全部病例均行常规MRI检查(矢状位、横轴位).分析两者引起的压缩骨折MRI征象,包括椎体和椎弓根的形态及信号改变、椎间盘增厚、椎体内真空现象和椎旁软组织形态.探讨两者之间的差别.结果两者在椎体和椎弓根形态及信号、椎体内真空现象、椎旁软组织形态上存在非常显著性差异(P<0.01).结论 MRI能准确显示骨质疏松性压缩骨折的形态及信号,与转移瘤之间有显著差异,大多能对二者做出鉴别诊断. 相似文献
4.
We present a patient with vertebrobasilar insufficiency, with vertigo and horizontal nystagmus, induced by turning the head to the right. Angiography demonstrated transient occlusion of the left vertebral artery at the atlantoaxial joint during rotation of the head. The pathogenesis and angiographic findings are discussed. 相似文献
5.
Endovascular stent implantation in patients with stenotic aortoarteriopathies: early and medium-term results. 总被引:1,自引:0,他引:1
Ernest S Siwik Stanton B Perry James E Lock 《Catheterization and cardiovascular interventions》2003,59(3):380-386
Data regarding stent implantation for stenotic aortoarteriopathy (SAA) are incomplete. We report on nine patients with this rare syndrome who underwent arterial stent implantation. Indications, results, and complications for patients with SAA were reviewed. Nine patients underwent 11 procedures. Twenty-two stents were implanted in the aorta or brachiocephalic vessels. Five patients had diffuse stenoses, three patients had middle aortic syndrome, and one patient had thoracic and abdominal coarctation. Associated diagnoses included Williams syndrome (2), neurofibromatosis (2), Takayasu's (1), and congenital rubella (1). Median gradient was 60 mm Hg (20-140 mm Hg). Poststent gradient was 15 mm Hg (0-60 mm Hg; P < 0.001). Additional stents were implanted in two patients and five underwent stent redilation. Two patients (22%) were found to have aneurysm formation. Stent implantation effectively provides gradient relief in SAA. Gradient reduction persists or is amenable to redilation. Importantly, however, uncomplicated stent implantation does not preclude aneurysm formation and may be more common than in traditional patient groups. 相似文献
6.
7.
Rauhut Friedhelm Reinhardt Volker Budach Volker Wiedemayer Helmut Nau Heinz-Eugen 《Neurosurgical review》1989,12(4):309-313
Ten patients suffering from intramedullary pilocytic astrocytomas (WHO-classification: astrocytoma grade I) were investigated catamnesticly. Combined surgery and radiotherapy was performed. Seven patients received neutron irradiation postoperatively. In four cases the neurological symptoms were improved after follow-up periods ranging from 33 to 89 months. The three other patients died after 6 to 21 months. The autopsy findings of a 14 year old child are presented. Our results are compared with reports in the literature. In addition, long-term problems of the spinal column are discussed. It seems that the combined surgical and neutron therapy improves the prognosis of pencil gliomas. 相似文献
8.
W. H. Kitchens C. M. Chase S. Uehara L. D. Cornell R. B. Colvin P. S. Russell J. C. Madsen 《American journal of transplantation》2007,7(12):2675-2682
Cardiac allograft vasculopathy (CAV) is a major source of late posttransplant mortality. Although numerous cell types are implicated in the pathogenesis of CAV, it is unclear which cells actually induce the vascular damage that results in intimal proliferation. Because macrophages are abundant in CAV lesions and are capable of producing growth factors implicated in neointimal proliferation, they are leading end-effector candidates. Macrophages were depleted in a murine heterotopic cardiac transplant system known to develop fulminant CAV lesions. C57BL/6 hearts were transplanted into (C57BL/6 x BALB/c)F(1) recipients, which then received anti-macrophage therapy with intraperitoneal carrageenan or i.v. gadolinium. Intraperitoneal carrageenan treatment depleted macrophages by 30-80% with minimal effects upon T, B or NK cells as confirmed by flow cytometry and NK cytotoxicity assays. Carrageenan treatment led to a 70% reduction in the development of CAV, as compared to mock-treated controls (p = 0.01), which correlated with the degree of macrophage depletion. Inhibition of macrophage phagocytosis alone with gadolinium failed to prevent CAV. Macrophages may represent the end-effector cells in a final common pathway towards CAV independent of T-cell or B-cell alloreactivity and exert their injurious effects through mechanisms related to cytokine/growth factor production rather than phagocytosis. 相似文献
9.
Oblique transcorporeal approach to anteriorly located lesions in the cervical spinal canal 总被引:2,自引:0,他引:2
Summary The technique of obliquely drilling out the postero-lateral part of the cervical vertebral bodies is described. It uses the antero-lateral (retro carotico-jugular) approach to control and displace the vertebral artery postero-laterally and to expose the lateral aspect of the vertebral bodies. It provides, through a wide field and with minimal retraction of the carotid artery and the internal jugular vein, an extensive view of the anterior aspect of the spinal cord. It has already been used to treat 15 anterior lesions compressing the spinal cord including neurinomas and osteophytes. 相似文献
10.
Gabrielle T. Lemire Éliane Beauregard‐Lacroix Philippe M. Campeau Stefan Parent Marjolaine Roy‐Beaudry Dorothée Dal Soglio Andrée Grignon Françoise Rypens Sandrine Wavrant Marie‐Ange Delrue 《American journal of medical genetics. Part A》2020,182(4):664-672
Our objectives were to describe fetal cases of vertebral defects (VD), assess the diagnostic yield of fetal chromosomal analysis for VD and determine which investigations should be performed when evaluating fetal VD. We performed a retrospective chart review for fetuses with VD seen between 2006 and 2015. Cases were identified from CHU Sainte‐Justine's prenatal clinic visits, postmortem fetal skeletal surveys, and medical records. Cases with neural tube defects were excluded. Sixty‐six fetuses with VD were identified at a mean gestational age of 20 weeks. Forty‐seven (71.2%) had associated antenatal anomalies, most commonly genitourinary, skeletal/limb, and cardiac anomalies. Thirteen mothers (19.7%) had pregestational diabetes (95% CI [10.1%–29.3%]). Fifty‐three cases had chromosomal analysis. Three had abnormal results (5.6%): trisomy 13, trisomy 22, and 9q33.1q34.11 deletion. Thirty‐four (51.5%) pregnancies were terminated, one led to intrauterine fetal demise and 31 (46.9%) continued to term. Of 27 children who survived the neonatal period, 21 had congenital scoliosis and 3 had spondylocostal dysostosis. Seven had developmental delay. In conclusion, prenatal evaluation of fetuses with VD should include detailed morphological assessment (including fetal echocardiogram), maternal diabetes screening, and chromosomal microarray if non‐isolated. Our findings provide guidance about management and counseling after a diagnosis of fetal VD. 相似文献