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Imaging the infant brain with MRI has improved our understanding of early neurodevelopment. However, head motion during MRI acquisition is detrimental to both functional and structural MRI scan quality. Though infants are typically scanned while asleep, they commonly exhibit motion during scanning causing data loss. Our group has shown that providing MRI technicians with real-time motion estimates via Framewise Integrated Real-Time MRI Monitoring (FIRMM) software helps obtain high-quality, low motion fMRI data. By estimating head motion in real time and displaying motion metrics to the MR technician during an fMRI scan, FIRMM can improve scanning efficiency. Here, we compared average framewise displacement (FD), a proxy for head motion, and the amount of usable fMRI data (FD ≤ 0.2 mm) in infants scanned with (n = 407) and without FIRMM (n = 295). Using a mixed-effects model, we found that the addition of FIRMM to current state-of-the-art infant scanning protocols significantly increased the amount of usable fMRI data acquired per infant, demonstrating its value for research and clinical infant neuroimaging. 相似文献
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Hal Blumenfeld 《Epilepsia》2007,48(S4):18-26
Summary: Functional magnetic resonance imaging (fMRI) has become a widely used imaging modality in the past decade in both human studies and animal models. Epilepsy presents unique challenges for neuroimaging due to subject movement during seizures, and the need to correlate the timing of often unpredictable seizure events with fMRI data acquisition. These challenges can readily be overcome in animal models of epilepsy. Animal models also provide an opportunity to investigate the fundamental relationships between fMRI signals and brain electrical activity through invasive studies not possible in humans. fMRI studies in animal models of epilepsy can enable us to correctly interpret fMRI signal increases and decreases in human studies, ultimately elucidating specific networks that will be targeted for improved treatment of epilepsy. 相似文献
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Moseley IF 《Neuroradiology》2000,42(1):1-8
A number of imaging techniques have been used to investigate changes produced in the brain by boxing. Most morphological
studies have failed to show significant correlations between putative abnormalities on imaging and clinical evidence of brain
damage. Fenestration of the septum pellucidum, with formation of a cavum, one of the most frequent observations, does not
appear to correlate with neurological or physiological evidence of brain damage. Serial studies on large groups may be more
informative. Magnetic resonance spectroscopy and cerebral blood flow studies have been reported in only small numbers of boxers;
serial studies are not available to date.
Received: 5 August 1991/Accepted: 5 August 1999 相似文献
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目的 通过对基于磁共振技术的功能性胃肠病(Functional Gastrointestinal Disorders,FGIDs)中枢病理变化相关文献进行回顾,分析该领域研究现状,以期为今后研究提供参考与借鉴。方法 以Web of Science收录1993年-2019年相关文献为对象,应用CiteSpace软件对文献的基本情况、研究的病种及重点脑区等进行共现分析,并绘制相关可视化图谱。结果 ①共获得文献151篇,发文量总体呈上升趋势,2017年文献发表数达到最高;②发表论文数量排名前3的国家分别是美国、中国、德国;③发文频次位于前3位的作者分别是Emeran A Mayer、K Tillisch、Fang Zeng;④主要是胃肠疾病类与影像学类相关杂志发文,核心期刊为Gastroenterology,Gut,Neurogastroenty and Molity;⑤对关键词进行聚类分析后,形成10个聚类群,分别为functional dyspepsia、brain response、endoanal ultrasound、prefrontal cortex、image cytometry、colonic function、functional constipation、acupuncture、resting-state、diffusion tensor imaging、default mode network。结论 ①基于神经影像技术,对FGIDs相关中枢机制的研究日益受到关注;②研究的主要病种是肠易激综合征、功能性消化不良和功能性便秘;③大脑前额叶皮质,前扣带回皮质,默认网络是FGIDs神经影像领域中备受关注的区域;④针灸是基于磁共振技术的FGIDs中枢机制研究中最常见的干预治疗方式。 相似文献
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Midori Mochizuki Yuki Uchiyama Kazuhisa Domen Tetsuo Koyama 《Journal of Physical Therapy Science》2023,35(2):156
[Purpose] To assess the clinical applicability of a novel automated tractography tool named XTRACT during acute stroke rehabilitation. [Participants and Methods] Three patients with left hemisphere stroke were sampled. Diffusion tensor images were acquired on the second week, and automated tractography was then applied. Tractography images and fractional anisotropy (FA) values in the corticospinal tract (CST) and arcuate fasciculus (AF) were assessed in relation to hemiparesis and aphasia. [Results] Patient 1 was nearly asymptomatic; FA in the left CST was 0.610 and that in the AF was 0.509. Patient 2 had severe hemiparesis and mild motor aphasia. Tractography images of the CST and AF were blurred; FA in the left CST was 0.295 and that in the AF was 0.304. Patient 3 showed no hemiparesis or aphasia at initial assessment. Tractography image of the CST was intact but that of the AF was less clear; FA in the left CST was 0.586 and that in the AF was 0.338. Considering the less clear images of the AF and lower FA value in Patients 2 and 3, further examinations for aphasia were performed, which revealed agraphia. [Conclusion] Visualization and quantification of neural fibers using automated tractography promoted planning acute care rehabilitative treatment in patients with stroke. 相似文献
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The peripartum period offers a unique opportunity to improve our understanding of how dramatic fluctuations in endogenous ovarian hormones affect the human brain and behavior. This notwithstanding, peripartum depression remains an underdiagnosed and undertreated disorder. Here, we review recent neuroimaging findings with respect to the neuroplastic changes in the maternal brain during pregnancy and the postpartum period. We seek to provide an overview of multimodal neuroimaging designs of current peripartum depression models of hormone withdrawal, changes in monoaminergic signaling, and maladaptive neuroplasticity, which likely lead to the development of a condition that puts the lives of mother and infant at risk. We discuss the need to effectively integrate the available information on psychosocial and neurobiological risk factors contributing to individual vulnerability. Finally, we propose a systematic approach to neuroimaging the peripartum brain that acknowledges important co-morbidities and variation in disease onset. 相似文献
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