全文获取类型
收费全文 | 11858篇 |
免费 | 484篇 |
国内免费 | 308篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 224篇 |
妇产科学 | 376篇 |
基础医学 | 246篇 |
口腔科学 | 13篇 |
临床医学 | 946篇 |
内科学 | 1179篇 |
皮肤病学 | 75篇 |
神经病学 | 127篇 |
特种医学 | 100篇 |
外科学 | 5445篇 |
综合类 | 1893篇 |
预防医学 | 493篇 |
眼科学 | 10篇 |
药学 | 1038篇 |
22篇 | |
中国医学 | 98篇 |
肿瘤学 | 358篇 |
出版年
2023年 | 172篇 |
2022年 | 316篇 |
2021年 | 383篇 |
2020年 | 398篇 |
2019年 | 335篇 |
2018年 | 370篇 |
2017年 | 325篇 |
2016年 | 392篇 |
2015年 | 455篇 |
2014年 | 995篇 |
2013年 | 892篇 |
2012年 | 800篇 |
2011年 | 794篇 |
2010年 | 631篇 |
2009年 | 637篇 |
2008年 | 635篇 |
2007年 | 597篇 |
2006年 | 489篇 |
2005年 | 421篇 |
2004年 | 342篇 |
2003年 | 278篇 |
2002年 | 183篇 |
2001年 | 180篇 |
2000年 | 122篇 |
1999年 | 154篇 |
1998年 | 103篇 |
1997年 | 123篇 |
1996年 | 106篇 |
1995年 | 128篇 |
1994年 | 107篇 |
1993年 | 79篇 |
1992年 | 39篇 |
1991年 | 31篇 |
1990年 | 13篇 |
1989年 | 25篇 |
1988年 | 13篇 |
1987年 | 19篇 |
1985年 | 47篇 |
1984年 | 68篇 |
1983年 | 39篇 |
1982年 | 76篇 |
1981年 | 36篇 |
1980年 | 30篇 |
1979年 | 28篇 |
1978年 | 49篇 |
1977年 | 19篇 |
1976年 | 26篇 |
1975年 | 48篇 |
1974年 | 41篇 |
1973年 | 37篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
目的探讨脾大部切除加断流术治疗小儿门静脉高压症的临床疗效。方法对16例确诊为门静脉高压症的患儿行脾大部切除加断流术。随访患儿恢复情况。结果16例患儿手术顺利,恢复良好,无死亡病例。无再发消化道出血、脾功能亢进表现,无脾切除术后凶险感染出现。结论保留脾脏的脾大部切除加断流术是治疗小儿门静脉高压症一种较好的手术方法。 相似文献
2.
M. Parikh M.D. J. Duncombe M.B. B.S. G.A. Fielding M.D. 《Surgery for obesity and related diseases》2006,2(5):99-522
BACKGROUND: Many mild-to-moderately obese individuals (body mass index [BMI] 30-35 kg/m(2)) have serious diseases related to their obesity. Nonoperative therapy is ineffective in the long term, yet surgery has never been made widely available to this population. METHODS: Between 1996 and 2004, 93 patients with a BMI of 30-35 kg/m(2) underwent laparoscopic adjustable gastric banding with the LAP-BAND. All patients were referred by their primary physician, entered into a comprehensive bariatric surgery program at one Australian center, and operated on by one surgeon. Data on all patients were collected prospectively and entered into an electronic registry. The study parameters included preoperative age, gender, BMI, presence of co-morbidities, percentage of excess weight loss, and resolution of co-morbidities. RESULTS: The mean age was 44.6 years (range 16-76), mean weight was 98 kg, and the mean BMI was 32.7 kg/m(2) (range 30-34). Of the 93 patients, 42 (45%) had co-morbidities, including asthma, diabetes, hypertension, and sleep apnea. The proportion of patients in follow-up was 79%, 85%, and 89% at 1, 2, and 3 years, respectively. The mean weight was reduced to 71 kg at 1 year, 72 kg at 2 years, and 72 kg at 3 years. The mean BMI was reduced to 27.2 +/- 2.2, 27.3 +/- 3.1, and 27.6 +/- 3.7 kg/m(2), respectively, and the mean percentage of excess weight loss was 57.9% +/- 24.5%, 57.6 +/- 29.3%, and 53.8% +/- 32.8% at 1, 2, and 3 years, respectively. At 3 years, the BMI was 18-24 kg/m(2) in 34%, 25-29 kg/m(2) in 51%, and 30-35 kg/m(2) in 10%. At 3 years, the percentage of excess weight loss was <25% in 10%, 25-50% in 24%, 50-75% in 51%, and >75% in 10%. The co-morbidities improved or completely resolved in most patients. No mortality occurred. CONCLUSION: We are very encouraged by this series of low BMI patients treated with the LAP-BAND. Their weight loss has been good, the complications have been minimal, and the co-morbidities have partially or wholly resolved. With additional study, it is reasonable to expect the weight guidelines for bariatric surgery to be altered to include patients with a BMI of 30-35 kg/m(2). 相似文献
3.
外伤性延迟性脾破裂的诊断和治疗(附21例报告) 总被引:1,自引:0,他引:1
目的探讨外伤性延迟性脾破裂的发病规律、临床特点、诊断和治疗方法。方法结合国内外资料及本组病例进行回顾性分析。结果明确诊断16例,误诊为肝破裂2例,宫外孕破裂2例,脾肿瘤1例。21例均手术治疗,行脾切除14例,其中保留副脾2例;脾切除加自体脾组织网膜内移植术3例;脾缝合修补术3例;脾部分切除术1例。死亡1例,原因有就诊晚、失血性休克。结论本病由于腹腔内出血与受伤时间间隔长,容易误诊。诊断除依靠病史、临床表现外,应及时进行腹腔穿刺、B超及CT检查。治疗以脾切除为主,可根据病情、脾破裂的程度以及是否有合并伤等情况采取保脾手术。 相似文献
4.
Lin Bo Wang Jian Guo Shen Li Feng Dong Chao Yang Xu Wen Jun Chen Shu Duo Xie Xiang Yang Song Ning Dai Xiao Ming Yuan 《Journal of gastrointestinal surgery》2008,12(8):1359-1363
We previously reported that lymphatic mapping using isosulfan blue can be used to identify sentinel nodes (SNs). This study
was undertaken to evaluate the feasibility of using the SN technique in treating early gastric cancer and to explore its usefulness
for minimal invasive surgery. Twenty-three patients with early gastric cancer who underwent SN biopsy were retrospectively
evaluated. Based on SN evaluation, individualized surgery was performed in five patients with T1N0M0 gastric cancer. When
pathological examination of frozen sections revealed metastasis in SNs, we performed a standard D2 gastrectomy. Laparoscopic
local resection was applied when the SN biopsy was negative. Our results showed that the success rate with SN biopsy in early
gastric cancer was 100%, as were the accuracy, sensitivity, and specificity. All five patients with early gastric cancer had
SNs negative for metastases both by frozen section and by postoperative pathology. Thus, all these patients underwent laparoscopic
local resection without extended lymphadenectomy. We conclude that SN biopsy is a useful tool to individualize the operative
procedure, and laparoscopic local resection can be safely performed using SN guidance in selected patients with early gastric
cancer. 相似文献
5.
Z. Malazgirt K. Topgul S. Sokmen S. Ersin A. G. Turkcapar H. Gok N. Gonullu M. Paksoy M. Ertem 《Hernia》2006,10(4):326-330
Most of the papers published on spigelian hernia are either case reports or small retrospective series. In this prospective
multicenter study, we aimed to outline the specific features of spigelian hernias and patients’ characteristics more clearly.
Surgeons enrolled patients to be entered into the database as they diagnosed and treated the hernias at will. The baseline
and surgical outcome parameters were noted in each patient. A painful mass was the main presenting complaint in half of 34
patients. Accurate preoperative diagnosis was possible in 31 patients. Open intraperitoneal mesh repair was the preferred
technique. The mean hospital stay and time until return to normal daily activities were 4.1 and 15.6 days. Although a rare
condition, diagnosis of a spigelian hernia is not difficult once remembered. Its surgical repair seems to cause few complications
and is very well tolerated by the patient. 相似文献
6.
A Alzahrani M Anvari B Dallemagne D Mutter J Marescaux 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2007,11(1):97-100
OBJECTIVE: We report on 3 patients who underwent laparoscopic antireflux procedures for persistent symptoms of GERD after biopolymer injection. METHODS: Experienced laparoscopic surgeons completed all 3 procedures laparoscopically. In 2 patients, there was an extramural extravasation of the polymer outside and adherent to the esophageal wall. In these patients, a partial posterior fundoplication was used. The third patient, who had the polymer material deposits removed preoperatively by endoscopic mucosal resection, underwent a Nissen fundoplication. RESULTS: Postoperative recovery was uneventful in all cases. At follow-up of 6 to 12 months, all patients were symptom free, off medical therapy, and experiencing no dysphagia. CONCLUSION: Surgical therapy for patients after failed biopolymer injection is safe and effective. The choice of surgery may depend on whether the polymer mass can be removed preoperatively. 相似文献
7.
Background The incidence rate of incisional hernias after open surgery has been reported to be higher than that of port site hernias
after laparoscopic surgery. No studies have compared the costs for the health care system in treating those two types of hernia.
Methods A systematic review was conducted to obtain the baseline data, and a decision analysis model was created to simulate the occurrence
and recurrence of incisional and port site hernias.
Results The overall risk of having incisional hernias was eight-times higher than that of having port site hernias (7.4% vs 0.9%).
A cost savings of £93 per patient can be generated for the health care system in the UK. Similar results were obtained for
Germany, Italy and France.
Conclusions The additional treatment costs for incisional hernia should be taken into account when the costs of a surgery performed by
open approach are compared with by laparoscopy. 相似文献
8.
腹腔镜辅助子宫肌瘤剔除术30例手术体会 总被引:1,自引:0,他引:1
目的:观察腹腔镜辅助子宫肌瘤剔除术的疗效,探讨腹腔镜辅助子宫肌瘤剔除术的可行性。方法:回顾性分析我院2008年全年30例子宫肌瘤患者的手术方法及手术结果。结果:30例患者全部治愈,平均手术时间78min,术后患者指征数据佳。结论:腹腔镜辅助子宫肌瘤剔除术综合了经典开腹及微创手术的优点,可以提倡。 相似文献
9.
Gastroesophageal reflux disease (GERD) is a common disease and can be successfully treated by laparoscopic fundoplication.
This article describes the technique of laparoscopic surgery for GERD with a focus on operative pitfalls. 相似文献
10.
背景:Nissen胃底折叠术(Nissen fundoplication,NF)已不是治疗胃食管返流性疾病(gastroesophageal reflux disease,GERD)的唯一、有效的方法。对于能降低胃酸的手术方式来讲,如高选择性迷走神经切断术(highly selective vagotomy,HSV),也不仅仅是一种辅助治疗方法。对高选择性迷走神经切断术联合Nissen胃底折叠术(Nissen fundoplication with highly selective vagotomy,NFHSV)治疗GERD的作用目前尚无完整的评价。方法:2003年6月~2005年6月8例女性病人接受NFHSV,8例均有6个月GERD病史,经药物治疗症状无缓解,有餐前痛、消化性溃疡或严重的胃炎。平均随访时间12个月,术前、术后进行烧心严重程度评分测定(heart burn severity score,HSS)。结果:平均手术时间110min,无手术并发症。1例术后须用质子泵抑制剂,术后经戒烟5个月后停药。8例术后症状和烧心严重程度评分测定有明显改善。结论:NFHSV是有效的联合手术方式,尚需要进一步的研究证实这一联合术式的完全有效性和安全性。 相似文献