鼠李糖脂分批式发酵动力学模型

根据3.7 L瑞士Bioengineer KLF2000型发酵罐分批发酵的实验数据,利用GraphPad Prism软件对假单胞菌BS-03产鼠李糖脂生物表面活性剂的发酵动力学模型进行非线性拟合,说明Logistic模型和L-P模型能较好的描述假单胞菌BS-03发酵过程中的菌体生长、鼠李糖脂合成和限制性基质的消耗动力学。     

汽车后送伤员附加装置隔振设计

采用钢丝绳隔振器设计了运输车后送伤员附加装置的隔振结构，并进行了隔振性能试验。5名受试者的试验结果表明，隔振装置的隔振性能良好，可衰减40％—70％的振动能量。本文为运输车后送伤员附加装置的隔振设计提供了一种新方法。     

磁流变减振器及在伤员运输车上的应用展望

磁流变液是1种新兴的智能材料。由于磁流变液快速可调的磁流变效应，使其广泛地应用于减振器、离合器、液压阀和抛光器等器件。文中主要介绍了磁流变液、磁流变效应和磁流变减振器的工作模式、特点以及在伤员运输车上的应用展望。     

Purification and characterization of a juvenile hormone binding protein from the hemolymph of the fourth instar tobacco hornworm, Manduca sexta

A protein which binds the insect juvenile hormone has been isolated from the hemolymph of the fourth instar tobacco hornworm, Manduca sexta (Lepidoptera). Bioassay and chemical characterization of the bound ligand from the purified binding protein indicates that this molecule is the primary macromolecule responsible for juvenile hormone transport in the hemolymph of this insect. The juvenile hormone binding protein has been purified using gel filtration, ion exchange chromatography and preparative polyacrylamide gel electrophoresis. The protein is a single polypeptide chain of about 28,000 daltons with a sedimentation coefficient of 2.2S and an isoelectric point of 5.0. Binding analysis using a hydroxyapatite batch assay indicates that the juvenile hormone binding protein has one binding site with a Ka of 1.2 times 10(7) M-1 at 4 degrees C.     

汶川地震医疗救援中的伤员接诊处置与转出管理

汶川地震医疗救援中，华西医院作为四川省重症伤员集中收治医院，立即从常态转到双轨应急状态，充分调度人力、物力，扩大骨科床位至680张；按伤员伤情进程分期重点处理、优化地震伤员接诊处置流程，保证有效救治；建立地震伤员转出通道。截至2008年6月2日，医院共接诊地震伤员2618例，向就近基层医院转诊经治疗病情稳定的轻症伤员648例。     

Batch to batch optimal control based on multiinput multioutput adaptive hinging hyperplanes prediction and Kalman filter correction

A batch to batch optimal control strategy based on multiinput multioutput adaptive hinging hyperplanes (MIMO AHH) prediction and Kalman filter correction is proposed for the products quality control of the batch process. The model of AHH is one kind of piecewise linear models and is extended to the MIMO case in this article. The MIMO AHH is then used to develop the predictive model of the batch process. Due to the model-plant mismatch and unknown disturbances, the optimal control policy calculated based on the MIMO AHH predictive model may not be optimal when applied to the true process. The Kalman filter is then utilized to correct the predictions of the current batch by considering the information of former batches. The effectiveness of the proposed strategy is verified through the simulation of a styrene batch polymerization reactor.     

Determining Adsorption Parameters of Potentially Contaminant-Releasing Materials Using Batch Tests with Differing Liquid-Solid Ratios

Adsorption parameters such as the distribution coefficient are required to predict the release behavior of contaminants using advection-dispersion models. However, for potentially contaminant-releasing materials (PCMs) such as dredged sludge and coal ash, these parameters cannot be obtained by conventional adsorption tests. This study developed a method to determine adsorption parameters for PCMs from a set of batch tests conducted in parallel as a function of the liquid-solid ratio (LS-parallel test). This LS-parallel test was performed on sandy soil derived from marine sediment using liquid-solid ratios from 1 to 300 L/kg. The water-contact time was also changed from 10 min to 28 d to elucidate the kinetics or equilibrium of contaminants released from the sample. Adsorption parameters were successfully obtained if the substance was under adsorption control. A column percolation test was performed to confirm the effectiveness of the obtained parameters. Good agreements were observed for SO₄²⁻ and B, but discrepancies remained for other substances such as F⁻ and As suggesting that improvements are necessary in both the LS-parallel test procedure and the advection-dispersion model.     

信息化分类后送在码头救护所战伤救护中的应用

现代战争卫勤保障信息化在我军卫勤保障中具有必然性和紧迫性,码头救护所使用大容量医疗信息卡、掌上分类器、二维码标识以及计算机等信息化手段对伤员实施分类后送,确定了信息化分类后送战伤伤员的流程,效果显著。本文就信息化技术在码头救护所战伤分类后送中应用的流程、优势,以及尚存在的问题进行探讨和总结,为战伤卫勤保障信息化提供经验。     

军地联合海上医疗救护演练伤员化妆的组织

目的 探讨军民融合模式下海上医疗救护演练中实战化伤员化妆技术,为建立军地融合模式下的海上医疗救护演练标准工作流程提供借鉴。方法 根据演练任务进行化妆用品准备;组织进行模拟伤员相关技能培训;制定标准化妆工作流程。结果 大批模拟伤员化妆组织有序、迅速,伤情模拟逼真,贴近实战,为实现海上医疗救护的实战化、模块化、信息化、标准化要求发挥了积极的作用。结论 实战化伤员化妆技术的实施有助于医务人员快速检伤分类、展开救治,更好的达到训练目标,从而提高医疗队员在现代战争海战伤的医疗救护能力。     

Covariance adjustment for batch effect in gene expression data

Batch bias has been found in many microarray gene expression studies that involve multiple batches of samples. A serious batch effect can alter not only the distribution of individual genes but also the inter‐gene relationships. Even though some efforts have been made to remove such bias, there has been relatively less development on a multivariate approach, mainly because of the analytical difficulty due to the high‐dimensional nature of gene expression data. We propose a multivariate batch adjustment method that effectively eliminates inter‐gene batch effects. The proposed method utilizes high‐dimensional sparse covariance estimation based on a factor model and a hard thresholding. Another important aspect of the proposed method is that if it is known that one of the batches is produced in a superior condition, the other batches can be adjusted so that they resemble the target batch. We study high‐dimensional asymptotic properties of the proposed estimator and compare the performance of the proposed method with some popular existing methods with simulated data and gene expression data sets. Copyright © 2014 John Wiley & Sons, Ltd.