利用Struts框架构建多层架构体系的PACS系统

在PACS系统设计中,随着业务逻辑的越来越复杂,如何提高PACS系统的执行效率、可复用性、可扩展性、可维护性、降低构建和维护成本,一直是业界普遍关注的焦点。基于可重用的框架技术逐渐成为业界研究和应用的新趋势。其中Struts框架利用MVC思想,为构建PACS应用系统提供了一种快速高效的开发方法,将大大节省开发人员的时间,提高开发效率。     

多层架构体系的PACS构建与实现

目的：提高PACS的可复用性、执行效率、可扩展性、可维护性、降低构建和维护成本。方法：利用基于MVC及面向对象思想的Struts及Hibernate框架构建PACS。结果：用此方法大大节省开发人员的时间,提高开发效率。结论：利用Struts及Hibernate框架构建PACS是一种快速高效的开发方法。     

垂体腺瘤中VEGF表达、血管生成与腺瘤侵袭性的关系

目的:探讨垂体腺瘤中血管生成的程度及其与肿瘤侵袭性的关系.方法:采用免疫组化SP法对47例垂体腺瘤(侵袭性25例、非侵袭性22例)病理标本和4例正常脑垂体标本检测血管内皮细胞生长因子(VEGF)的表达和第Ⅷ因子相关抗原(F8-RA)组化染色行微血管记数(MVC)并作统计学分析.结果:侵袭性垂体腺瘤中VEGF表达及MVC均显著大于非侵袭性腺瘤(P＜0.05),VEGF表达强度与MVC两者在垂体腺瘤血管生成中呈正相关(r=0.7625, P＜0.01).结论:腺瘤组织中的VEGF的异常表达和MVC能够准确地反映垂体腺瘤血管的生成程度与腺瘤侵袭密切相关,可为临床上评价垂体腺瘤侵袭性及预后提供生物学上的参考指标.     

胃癌组织中微血管数量与肝转移的关系

目的 本试验拟通过对胃癌组织中微血管的数量、血管分布方式的检测,探讨其与肝转移的关系。方法 收集胃癌石蜡标本７５例,其中肝转移２９例,采用兔抗人第Ⅷ因子相关抗体,ＳＡＢＣ免疫组化方法,在２００倍镜下计数每个病例癌组织中的血管数,以均值作为区分高、低血管组的标准。按血管在癌组织中的分布方式分为：肿瘤内型和间质型。检测,胃癌组织中的微血管数量和分布方式,比较与肝转移的关系。结果 全组病例的微血管数范围     

胃癌组织中微血管计数与肝转移的相关性研究

目的 :应用第Ⅷ因子相关性抗原 ,行SABC免疫组化染色 ,研究胃癌组织中微血管计数及分布方式与肝转移的相关性。方法 :全组 75例胃癌标本 ,制成石蜡切片 ,SABC免疫组化染色后 ,2 0 0倍显微镜下计数 5个血管密度最高区中微血管数及微血管在癌组织内的分布方式。结果 :全部病例癌组织中微血管 (MVC)均值为 16 .70 7± 10 .718,MVC≥ 16者 ,肝转移发生率较MVC <16者明显增加 (P <0 .0 5 )。MVC分布为肿瘤内型者以分化型癌为多 ,较间质型更易发生肝转移。高血管组比低血管组预后差。结论 :胃癌组织中MVC的高低是胃癌预后的一个有用的预测指标。     

Evaluating the “cushion effect” among children in frontal motor vehicle crashes

Background

The “Cushion Effect,” the phenomenon in which obesity protects against abdominal injury in adults in motor vehicle accidents, has not been evaluated among pediatric patients. This work evaluates the association between subcutaneous fat cross-sectional area, quantified using analytic morphomic techniques and abdominal injury.

Effects of movement imitation training in Parkinson's disease: A virtual reality pilot study

BackgroundHypometria is a clinical motor sign in Parkinson's disease. Its origin likely emerges from basal ganglia dysfunction, leading to an impaired control of inhibitory intracortical motor circuits. Some neurorehabilitation approaches include movement imitation training; besides the effects of motor practice, there might be a benefit due to observation and imitation of un-altered movement patterns. In this sense, virtual reality facilitates the process by customizing motor-patterns to be observed and imitated.ObjectiveTo evaluate the effect of a motor-imitation therapy focused on hypometria in Parkinson's disease using virtual reality.MethodsWe carried out a randomized controlled pilot-study. Sixteen patients were randomly assigned in experimental and control groups. Groups underwent 4-weeks of training based on finger-tapping with the dominant hand, in which imitation was the differential factor (only the experimental group imitated). We evaluated self-paced movement features and cortico-spinal excitability (recruitment curves and silent periods in both hemispheres) before, immediately after, and two weeks after the training period.ResultsMovement amplitude increased significantly after the therapy in the experimental group for the trained and un-trained hands. Motor thresholds and silent periods evaluated with transcranial magnetic stimulation were differently modified by training in the two groups; although the changes in the input–output recruitment were similar.ConclusionsThis pilot study suggests that movement imitation therapy enhances the effect of motor practice in patients with Parkinson's disease; imitation-training might be helpful for reducing hypometria in these patients. These results must be clarified in future larger trials.     

An inverted seated posture decreases elbow flexion force and muscle activation

The purpose of this study was to determine if discrepancies exist between upright and inverted seated positions in isometric maximal voluntary contraction (MVC) elbow flexor force, MVC force produced in the first 100 ms (F100), MVC rate of force development, electromyographic (EMG) activity of the biceps and triceps as well as heart rate and blood pressure. The results showed significantly (p < 0.01) higher MVC force (543.6 ± 29.6 vs. 486.5 ± 23.0 N), F100 (328.3 ± 94.5 vs. 274.6 ± 101.8 N), rate of force development (p = 0.003) (1,851.9 ± 742.2 vs. 1,591.0 ± 719.6 N s⁻¹) and biceps brachii EMG activity (48%, p < 0.01) in the upright versus inverted condition. There were relatively greater co-contractions with the inverted position (p < 0.01) due to the lack of change in triceps’ EMG and the substantial decrease in biceps’ EMG. There were no significant changes in trunk EMG activity. With inversion, there were significant decreases in heart rate (16.8%), systolic (11.6%) and diastolic (12.1%) blood pressures (p < 0.0001). These results illustrate decrements in neuromuscular performance with an inverted seated posture which may be related to an altered sympathetic response.