Determination of blood viscosity in vitro with a microglass fiber viscosimeter

Summary The micro-rheological property of blood was investigated with a new micro method. Principle: a glass fiber ( 10 , l=2.0 cm), driven by a constant force, traverses a blood sample. The speed of the glass fiber is directly proportional to the viscosity of the blood. Because of the small diameter of the fiber, the method is considered to be more sensitive to the intercellular friction of the erythrocytes. The methodical error was less than ±2%. The values obtained with the new method resembled those of coaxial viscosimeters.     

生物物质的介电测量技术

本文根据传输线法介电测量原理建立起100KHz～500MHz频率范围的生物物质介电测量系统,该系统由网络分析仪、同轴线腔式传感器及测温控温装置等组成,并由计算机实现自动采样与分析。对测量误差的来源作了详细分析,一定修正和补偿条件下,本文制做的腔式传感器适用于整个频率范围。对人全血和人脑组织等高含水量物质的介电常数测量误差小于3％,电导率误差小于2％。     

Embolization with “Ethibloc” of vascular tumors and arteriovenous malformations in the head and neck

Summary Ethibloc has been used almost exclusively until now for embolization of tumors and bleeding vessels in the liver and kidney. Unlike with Gelfoam-particles, there is no recanalization. The resorption occurs so slowly that there is no interference with the necrosis of the embolized tumor. Due to its low viscosity, it passes catheters with thin lumina and fills the capillary bed of the tumor without danger of reaching the venous vessels. In this paper we describe a new technic of percutaneous catheter-embolization with Ethibloc using a coaxial catheter which we believe enhances safety and effectiveness. It has been successfully used in five patients. In the meantime two more patients have been treated successfully.Presented in part at the 17th Annual Meeting of the German Society of Neuroradiology, 9–10 October 1981 in Tübingen, FRG.     

Glue embolization of a ruptured celiac trunk pseudoaneurysm via the gastroduodenal artery

Percutaneous transcatheter embolization of splanchnic artery aneurysms is a minimally invasive and alternative therapy to conventional surgical intervention. Due to a high-grade stenosis at the origin of the celiac trunk, a retrograde approach to the celiac trunk pseudoaneurysm via the gastroduodenal artery was necessary. To prevent undesirable embolization into the peripheral left gastric artery initial occlusion of the central portion of the left gastric artery was performed with microcoils using a Tracker catheter. Complete occlusion of the celiac trunk itself and the short adjacent segments of the celiac artery was achieved by using a mixture of N-butyl-2-cyanoacrylate and ethiodized oil as the embolizing agent. Received: 22 June 1999; Revised: 7 September 1999; Accepted: 1 October 1999     

输卵管阻塞介入治疗51例临床分析

目的：探索输卵管阻塞性不孕的诊断与非血管介入治疗方法。方法：对51例输卵管阻塞患者，采用9F、5．5F、3F用轴导管导向法，在X线监视下经阴道放入，分别置于宫颈部、子宫角部及左右输卵管，造影证实后，行再通术。结果：技术操作成功率100％，无严重并发症，随访3～18个月，51例双侧输卵管通畅，有效率达96％。结论：输卵管阻塞同轴导管导丝导向法介入治疗是一种简便、实用、效果较好的一种治疗方法。     

A novel coaxial tube catheter for central nervous system infusions: performance characteristics in brain phantom gel

We tested a novel neurocatheter in a brain-tissue gel model of drug infusion via convection-enhanced delivery (CED) for the treatment of a variety of neurological diseases. CED is an alternative to systemic administration of agents by intravenous or oral routes, which are often less effective or carry risk of systemic side effects. We investigated two co-axial tube devices, with outer diameters of 1.6?mm and 2.0?mm. Bromophenol blue dye was infused into 400?ml of 0.6% agarose gel at 1?μl/min for 1?h, with/without the inner and outer tubes Luer-locked at the proximal end, with/without the inner tube primed, and with/without the inner tube preloaded into the outer tube upon insertion into the gel. The unlocked, primed, and unloaded configuration produced infusions that resulted in significantly less (p?<?0.05) entrapped air escaping into the gel and resulted in no reflux of infusate.     

经皮胸穿活检的临床应用及并发症探讨

目的探讨在CT引导下应用半自动同轴活检枪对胸部占位性病变经皮穿刺活检的临床可行性及安全性。方法56例胸部占位性病变的患者,采用半自动同轴活检枪在CT引导下行经皮穿刺活检术并送病理检查,统计穿刺活检的成功率及病理检查结果;术后行CT扫描,统计穿刺活检的并发症及穿刺活检的安全性。结果半自动同轴活检枪穿刺活检的成功率为92.9%(52/56);病理检查结果:穿刺成功的52例患者中,腺癌18例、鳞癌10例、小细胞癌9例、淋巴瘤2例、胸腺瘤2例、转移癌8例、真菌感染1例、肉芽肿性炎2例;穿刺活检的并发症:合并出血和或咯血的发生率32%(18/56)、气胸发生率19.6%(11/56)、死亡率1.8%(1/56);未发生穿刺点感染、针道种植转移等其他并发症。结论半自动同轴活检枪在CT引导下对胸部占位性病变经皮穿刺活检术是一种创伤小、相对安全、确诊率高的诊断方法,可在胸部占位性疾病临床诊断中广泛推广应用。     

Enhanced antibacterial nanocomposite mats by coaxial electrospinning of polycaprolactone fibers loaded with Zn-based nanoparticles

ZnO and Zn acetate nanoparticles were embedded in polycaprolactone coaxial-fibers and uniaxial-fibers matrices to develop potential antibacterial nanocomposite wound dressings (mats). Morphology, composition, wettability, crystallinity and fiber structure of mats were characterized. Antibacterial properties of mats were tested against E. coli and S. aureus by turbidity and MTT assays. The effect of UVA illumination (prior to bacteria inoculation) on mats’ antibacterial activity was also studied. Results showed that a coaxial-fibers design maintained nanoparticles distributed in the outer-shell of fibers and, in general, enhanced the antibacterial effect of the mats, in comparison to conventional uniaxial-fibers mats. Results indicated that mats simultaneously inhibited planktonic and biofilm bacterial growth by, probably, two main antibacterial mechanisms; 1) release of Zn²⁺ ions (mainly from Zn acetate nanoparticles) and 2) photocatalytic oxidative processes exerted by ZnO nanoparticles. Antibacterial properties of mats were significantly improved by coaxial-fibers design and exposure to UVA-light prior to bacteria inoculation.     

用自制同轴导管行选择性输卵管造影及再通术的临床应用

研究选择性输卵管插管造影及再通治疗的临床价值，验证自制同轴导管的可能性，并与国外器械运用情况进行比较。选择性输卵管造影对病变的诊断效果高于传统子宫碘油造影。用自制同轴导管行再通治疗方法简便易行，安全可靠，器械成本低廉，易操作。此方法可取代传统方法。