慢性强迫游泳应激对大鼠情绪和脑细胞外信号调节激酶磷酸化水平的影响

目的探讨慢性强迫游泳应激对大鼠情绪和脑细胞外信号调节激酶磷酸化(P-ERK1/2)水平的影响。方法将30只SD雄性大鼠随机分为游泳应激组、装置对照组和空白对照组,每组10只。游泳应激组每天接受5min的游泳应激,装置对照组每天接受5min的新异场景应激,均连续14 d,空白对照组不进行任何干预,然后观察大鼠行为(体质量增长量、旷场测验和糖精水溶液偏好测验)。采用免疫印迹法测定大鼠海马和前额叶皮质的P-ERK1/2。结果(1)游泳应激组在应激7d和应激14d的体质量增长[分别为(75±22)g和(70±24)g]均低于空白对照组[分别为(101±35)g和(115+47)g],均P＜0.05。(2)装置对照组的粪便排泄量[(1.4±1.9)粒]多于空白对照组[(0.4±1.0)粒]和游泳应激组[(0.1±0.3)粒],均P＜0.05；而游泳应激组的水平活动距离[(2077±1245)cm]少于空白对照组[(2990±1038)cm]和装置对照组[(3110±1462)cm],均P＜0.05。(3)游泳应激组的糖精水溶液摄入量[(11±6)g]和糖精水溶液摄入量占总液体摄入量的比例[(37±16)％]均低于空白对照组[分别为(15±4)g和(47±15)％],均P＜0.05。(4)游泳应激组在海马[(46±95)％]和前额叶皮质[(65±24)％]的P-ERK2水平均低于空白对照组[分别为(76±30)%和(99±42)%],均P＜0．05。结论慢性强迫游泳应激能诱发大鼠的抑郁情绪,降低P-ERK2在海马和前额叶皮质的水平。     

Emotion-related cerebral asymmetry: hemodynamics measured by functional ultrasound

This study assessed the use of transcranial Doppler ultrasound in detecting selective changes in cerebral blood flow velocity during emotional processes. The role of the respective hemispheres in emotional processing is controversial. Cerebral control of emotional processing has previously been investigated by analysis of patients with unilateral brain damage, experiments with selective stimulation of only one hemisphere, and more recently by imaging techniques measuring local cerebral blood flow. We investigated mean flow velocity continuously and simultaneously in both the right and left middle cerebral arteries (MCAs) in 16 healthy right-handed young subjects at rest and during the performance of three tasks: task 1: 15 slides with nonemotional content; task 2: 15 slides with negative emotional content; task 3: 15 slides with nonemotional content with different content from that in task 1. The three tasks produced significantly different effects on the right and left hemispheres. During the two nonemotional tasks the increase in mean flow velocity over basal values was similar in the two MCAs (task 1: left MCA = 3.27 ± 1.9%; right MCA = 3.63 ± 2.1%; task 3: left MCA = 2.42 ± 0.7%; right MCA = 2.56 ± 1.3%); the negative emotional task was accompanied by a significantly higher increase in the right (11.31 ± 1.6%) than in the left MCA (4.72 ± 3.7%; analysis of variance two-way interaction: side of recording x task, F = 43.6, P < 0.001). These results show the possibility of obtaining specific functional information from bilateral transcranial Doppler ultrasound and suggest the involvement of the right hemisphere in emotional processing. Received: 4 March 1999 Received in revised form: 29 June 1999 Accepted: 5 August 1999     

在沪就读藏族初中学生情绪和自我意识相关性研究

目的了解在沪读书藏族中学生情绪和自我意识之间的关系,以便为藏族学生心理咨询提供依据。方法应用流调用抑郁量表、PiersHarris儿童自我意识量表(PHSS)对藏族中学生672名进行调查。结果藏族中学生抑郁情绪的检出率为14.4%。男生在行为分量表、合群分量表的得分低于女生;躯体外貌分量表得分为男生高女生低。有抑郁情绪学生的PHSS总分和各分量表得分均低于无抑郁情绪的学生,差别有统计学意义。抑郁情绪与自我意识总分及各分量表得分呈负相关。结论在沪就读藏族中学生的情绪状态与自我意识有关,且相互影响。     

Measuring positive affect and well-being after spinal cord injury: Development and psychometric characteristics of the SCI-QOL Positive Affect and Well-being bank and short form

ObjectiveTo develop an item response theory (IRT)-calibrated spinal cord injury (SCI)-specific Positive Affect and Well-being (PAWB) item bank with flexible options for administration.DesignQualitative feedback from patient and provider focus groups was used to expand on the Neurological Disorders and Quality of Life (Neuro-QOL) positive affect & well-being item bank for use in SCI. New items were created and revised based on expert review and patient feedback and were then field tested. Analyses included confirmatory factor analysis, graded response IRT modeling and evaluation of differential item functioning (DIF).SettingWe tested a 32-item pool at several rehabilitation centers across the United States, including the University of Michigan, Kessler Foundation, Rehabilitation Institute of Chicago, the University of Washington, Craig Hospital and the James J. Peters/Bronx Department of Veterans Affairs hospital.ParticipantsA total of 717 individuals with SCI answered the PAWB questions.ResultsA unidimensional model was observed (Confirmatory Fit Index = 0.947; Root Mean Square Error of Approximation = 0.094) and measurement precision was good (reliability in theta of –2.9 to 1.2 is roughly equivalent to classical reliability of 0.95 or above). Twelve items were flagged for DIF, however, after examination of effect sizes, the DIF was determined to be negligible and would have little practical impact on score estimates. The final calibrated item bank resulted in 28 retained itemsConclusionsThis study indicates that the Spinal Cord Injury – Quality of Life PAWB bank represents a psychometrically robust measurement tool. Short form items are also suggested and a computer adaptive test is available.     

老年妇科腔镜手术患者心理负面情绪的心理护理效果观察

目的研究分析心理护理改善老年妇科腔镜手术患者心理负面情绪的效果。方法将2016年1月-2017年12月期间我院收治的80例老年妇科腔镜手术患者随机分为对照组和观察组两组,每组40例,对照组采取常规护理,观察组采取心理护理干预,观察对比两组患者满意度及护理前后SDS、SAS及PSQI评分情况。结果观察组护理满意度达90%,明显高于对照组75%,差异具有统计学意义(P<0.05)。干预前,两组患者SDS、SAS及PSQI评分相近无显著差异(P>0.05),干预后观察组SDS、SAS及PSQI评分明显优于对照组,差异具有统计学意义(P<0.05)。结论在老年妇科腔镜手术患者中实施心理护理干预,能有效改善患者焦虑、抑郁情况,提高患者睡眠治疗,提升手术治疗效果。     

Emotion differentiation in autism spectrum disorder

Autism spectrum disorder (ASD) is commonly associated with reduced ability to recognize emotions in others. It is less clear however, whether ASD is also associated with impaired knowledge of one's own emotions. In the current study we present a first examination of how much knowledge individuals with ASD have about their emotions by investigating their ability to differentiate between emotions. Across two lab tasks that measured to what extent and how people differentiate between their own feeling states and semantic emotion terms, results showed that ASD individuals differentiated less than typically developing individuals. Yet, both groups of participants similarly categorized emotions according to previously established theoretical categories. These findings indicate that while both give similar meaning to emotions, individuals with ASD make less subtle distinctions between emotions. With low levels of emotion differentiation being linked to reduced well-being, these findings may help to better understand the high prevalence of internalizing problems associated with ASD.     

The body as theatre of passions and conflicts: Affects,emotions, and defences

We can say that emotions and affects, as well as psychological defences against anxieties, find their channels of expression through the body and movements in ways that often are hidden or not immediately obvious. This paper will address the ways in which Laban Movement Analysis (LMA) (1950), and the studies by Kestenberg (1975 Kestenberg, JS. 1975. Children and parents: Psychoanalytic studies in development, New York: Jason Aronson.  [Google Scholar], 1977, 1999 Kestenberg, JS, Amighi, J, Loman, S, Lewis, P and Sossin, KM. 1999. The meaning of movement. Developmental and clinical perspectives of the KMP, The Netherlands: Gordon and Breach.  [Google Scholar]), Bartenieff (1980 Bartenieff, I and Lewis, D. 1980. Body movement: Coping with the environment, Amsterdam: Gordon and Breach Publishers.  [Google Scholar]), Whitehouse (1979 Whitehouse, MS. 1979. “C. G. Jung and Dance Therapy, Two Major Principles”. In Authentic movement: Essays by Mary Starks Whitehouse, Janet Adler and Joan Chodorow, Edited by: Pallaro, P. London: Jessica Kingsley Publishers. 1999 [Google Scholar], 1988), and Chodorow (2001 Chodorow, J. 2001. Emotions and the archetypal imagination Presented at the National Conference of Jungian Analysts, February [Google Scholar]) can be used to facilitate the understanding of the psychodynamic processes at their source, regarding emotions/affects in relation to the defence mechanisms. In a Dance Movement Therapy (DMT) setting, processes like identification, body empathy, and somatic countertransference are some of the tools to understand and to give meaning to the client's clinical issues, according to the developmental level of their needs. A specific quality of attention, respect, and containment is required for the creation of trust. The capacity to observe, to “witness” (Adler, 1987 Adler, J. 1987. “Who is the witness”. In Authentic movement: Essays by Mary Starks Whitehouse, Janet Adler and Joan Chodorow, Edited by: Pallaro, P. London: Jessica Kingsley Publishers. 1999 [Google Scholar]), and to “listen” deeply offers a way to work with the subtle nuances of movement expression and to understand their hidden meaning in a therapeutic way.     

Stress and welfare: two complementary concepts that are intrinsically related to the animal's point of view

The closely associated concepts of welfare and stress may be considered as opposites since welfare cannot be achieved under stress and vice versa. Stress was first considered as an unspecific response to any challenge taxing the organism's resources where the HPA axis plays a central role [Selye H. A syndrome produced by diverse nocuous agents. Nature 1936:32]. Along the same lines, welfare was considered as the state of an individual on a continuum between poor and good depending on the efforts required to adapt to the environment [Broom DM. Animal welfare: concepts and measurement. J Anim Sci 1991;69:4167-75]. However, these views cannot explain opposite results such as up- vs. down-regulation of the HPA axis and hypo- vs. hyper-behavioural reactivity under chronic stress. Later, it was shown that aversive situations trigger stress responses only if the individual perceives them as aversive. Mason [Mason JW. A re-evaluation of the concept of 'non-specificity' in stress theory. J Psychiatr Res 1971;8:323-33] suggested that the unspecificity of stress responses originates from a common emotion that produces them. Welfare has also been defined in terms of emotional states by Dawkins [Dawkins MS. Animal suffering, the science of animal welfare. London: Chapman and Hall Ltd.; 1980] and Duncan [Duncan IJH. Welfare is to do with what animals feel. J Agric Environ Ethics 1993;6:8-14]. Hence, both concepts are linked to mental states. Recent advances in psychology suggest that the very nature of an emotion results from a series of evaluations of the triggering situation that the individual makes based on criteria including novelty, predictability, controllability, and others [Scherer KR. Appraisal considered as a process of multi-level sequential checking. In: Scherer KR, Schorr A, Johnstone T, editors. Appraisal processes in emotion: theory, methods, research. New York: Oxford University Press; 2001. p. 92-120]. It is therefore suggested that the discrepancies found in the literature in terms of responses of the HPA axis or modification of behaviour under aversive conditions may stem from differences in the way a situation is evaluated. It is argued that stress comes from the animal's evaluation of the outcome of a situation, and that welfare is the state resulting from that evaluation.