全文获取类型
收费全文 | 1978篇 |
免费 | 69篇 |
国内免费 | 35篇 |
专业分类
耳鼻咽喉 | 23篇 |
儿科学 | 41篇 |
妇产科学 | 25篇 |
基础医学 | 56篇 |
口腔科学 | 45篇 |
临床医学 | 281篇 |
内科学 | 178篇 |
皮肤病学 | 14篇 |
神经病学 | 250篇 |
特种医学 | 348篇 |
外科学 | 508篇 |
综合类 | 175篇 |
预防医学 | 23篇 |
眼科学 | 18篇 |
药学 | 60篇 |
2篇 | |
中国医学 | 5篇 |
肿瘤学 | 30篇 |
出版年
2023年 | 16篇 |
2022年 | 52篇 |
2021年 | 67篇 |
2020年 | 75篇 |
2019年 | 42篇 |
2018年 | 54篇 |
2017年 | 51篇 |
2016年 | 50篇 |
2015年 | 74篇 |
2014年 | 131篇 |
2013年 | 110篇 |
2012年 | 99篇 |
2011年 | 100篇 |
2010年 | 75篇 |
2009年 | 109篇 |
2008年 | 91篇 |
2007年 | 60篇 |
2006年 | 83篇 |
2005年 | 87篇 |
2004年 | 64篇 |
2003年 | 45篇 |
2002年 | 62篇 |
2001年 | 53篇 |
2000年 | 42篇 |
1999年 | 24篇 |
1998年 | 28篇 |
1997年 | 23篇 |
1996年 | 37篇 |
1995年 | 26篇 |
1994年 | 29篇 |
1993年 | 29篇 |
1992年 | 16篇 |
1991年 | 17篇 |
1990年 | 14篇 |
1989年 | 17篇 |
1988年 | 14篇 |
1987年 | 12篇 |
1986年 | 20篇 |
1985年 | 16篇 |
1984年 | 13篇 |
1983年 | 6篇 |
1982年 | 12篇 |
1981年 | 2篇 |
1980年 | 6篇 |
1979年 | 7篇 |
1978年 | 10篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1972年 | 2篇 |
1971年 | 2篇 |
排序方式: 共有2082条查询结果,搜索用时 15 毫秒
1.
Comparative outcomes of vascular access in patients older than 70 years with end-stage renal disease
Deokbi Hwang Sujin Park Hyung-Kee Kim Seung Huh 《Journal of vascular surgery》2019,69(4):1196-1206.e5
Objective
The advantage of arteriovenous fistulas (AVFs) in older patients requiring dialysis is controversial. We reviewed our vascular access experience in patients ≥70 years of age (older group) compared with younger patients.Methods
We analyzed consecutive patients who underwent access surgery between 2013 and 2016. Primary success (PS) and primary patency (PP) data were analyzed between the older and younger groups before and after propensity score matching of the patients' characteristics and access composition. PS was defined as the achievement of access function that was amenable to two sessions of successful cannulation without early occlusion or maturation failure requiring revision. PP was defined as the time with uninterrupted patency without intervention.Results
A total of 594 consecutive accesses were created among 563 patients, of whom 119 were allocated into each group after propensity score matching. In the whole cohort, 193 accesses (32.5%) were performed in older patients. AVFs were performed in 130 (67.4%) older patients and 293 (73.1%) younger patients. Regarding AVFs, the PS rate (83.6% in the older group vs 94.3% in the younger group; P = .001) and the overall PP at 6 and 12 months (73.1% and 57.1%, respectively, in the older group vs 86.7% and 77.7%, respectively, in the younger group; P = .009) were lower in the older group than in the younger group. However, no differences were found in the PS and PP rates for arteriovenous grafts between groups. Regarding the AVF location, the PS rate for forearm AVFs was significantly lower in the older group than in the younger group (76% vs 93%; P < .001); however, the PS rate of the upper arm was not different between the groups (94% vs 97%; P = .425). In the patients with PS, the PP rate of AVFs was similar between the two groups. In the older group with forearm AVFs, the median diameter of the radial artery was larger in the patients with PS than in the patients without PS (2.20 mm with PS vs 2.00 mm without PS; P = .008). The propensity score matching results demonstrated similar trends for the whole cohort, with lower PS (P = .042) and PP rates (P = .023) for AVF in the older group.Conclusions
The outcomes after AVF were poorer in the older group than in the younger group, which was primarily due to unsatisfactory outcomes in patients with forearm AVFs. Thus, stricter criteria, especially regarding the radial artery diameter, should be applied for forearm AVFs in older patients, and additional research is necessary to delineate the risk factors for primary failure. 相似文献2.
Kevin L. Greason M.D. Jose A. Acosta M.D. Thomas J. Magrino M.D. Moogil Choe M.D. 《Diseases of the colon and rectum》1996,39(6):702-704
PURPOSE: This study was undertaken to clarify the importance of bleeding vascular ectasia of the colon as the etiology of massive lower gastrointestinal hemorrhage in patients 40 years of age or younger. METHODS: An otherwise healthy 21-year-old male was admitted to a tertiary medical center with massive lower gastrointestinal hemorrhage. Technetium-labeled red blood cell scan, selective visceral angiography, and colonoscopy identified the source of bleeding as vascular abnormality of the descending colon. Segmental colonic resection was performed. RESULTS: Histologic review of the specimen demonstrated a vascular ectasia. The patient recovered uneventfully and has had no further stigmata of hemorrhage. A review of the literature was undertaken to make clear the significance of vascular ectasia as the source for massive colonic hemorrhage in the young adult. CONCLUSION: This is the first report that documents histologically a vascular ectasia as the source of massive lower gastrointestinal hemorrhage in an otherwise healthy patient less than 40 years of age. Vascular ectasia is an uncommon cause of lower gastrointestinal hemorrhage in the young adult.The Chief, Bureau of Medicine and Surgery, Navy Department, Washington, DC, Clinical Investigation Program sponsored this report #84-16-1968-532, as required by HSETCINST 6000.41A. The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States Government. 相似文献
3.
Summary Two contrasting cases of cervical intramedullary cavernous angioma in young female patients are reported. One patient had a 3-year course of step-wise progressive tetraparesis; at each of the five events intramedullary bleeding from a cryptic vascular malformation at C6–7 level was diagnosed by MRI. The other patient presented with one episode which led to MRI diagnosis of a vascular malformation at the C2 level. Both patients eventually underwent complete surgical excision of the angioma with subsequent steady improvement of the neurological deficit. 相似文献
4.
G. Herdman C. U. Dussa R. Watura M. Cobby 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2005,15(1):66-68
Two young men with longstanding suprapatellar masses are presented. The initial clinical diagnosis was of a synovial or soft tissue tumour. Magnetic resonance imaging showed the features of an arteriovenous malformation (AVM). Surgical exploration and biopsy confirmed the diagnosis. AVMs, although rare, should be considered as a possible diagnosis of a peri-articular swelling of the knee. 相似文献
5.
肝动脉栓塞治疗肝癌肝动脉-门静脉瘘所致的大量腹腔积液 总被引:2,自引:0,他引:2
目的:探讨肝动脉栓塞治疗肝癌肝动脉-门静脉瘘(APF)所致大量腹腔积液的临床应用价值。方法:并发高流量APF和大量腹腔积液的肝癌患者9例,以明胶海绵颗粒栓塞载瘘动脉,消除或减少APF,用碘化油尽量栓塞肝癌病灶。结果:APF消失7例,少量残留2例;门静脉血流方向全部由逆肝转为向肝;肝癌病灶内碘化油沉积良好6例;术后2周内腹腔积液完全消失5例,少量残余4例;2周后肝功复查,5例肝功能原有明显损害者全部明显改善;全部病例原有腹胀、腹痛、厌食、乏力症状不同程度缓解。结论:对肝癌并高流量APF所致腹腔积液,动脉栓塞治疗简单、安全、有效。 相似文献
6.
小血管套叠粘接吻合法在血液透析者中建立动静脉内瘘的应用 总被引:3,自引:1,他引:2
慢性肾病患者常需要建立动静脉内瘘进行透析,常规间断缝合法吻合动静脉难度大、耗时长。为了缩短吻合时间,提高远期通畅率,进行了套叠粘接吻合法建立动静脉内瘘的实验研究,并将这一方法应用于透析患者建立动静脉内瘘的血管吻合。将动脉端套入静脉端,只需吻合两针,用医用胶封闭吻合口。经8个月观察,通畅率达100%,血流量均超过300ml/min。达到了透析需要。 相似文献
7.
Lorenzo E. Derchi Carlo Martinoli Roberto Pontremoli Stefano Saffioti Caterina Pastorino 《European radiology》1993,3(2):186-189
Two patients with arteriovenous fistulas of the native kidney occurring after needle biopsy were evaluated using duplex and color Doppler ultrasonography. The first patient had a fistula with associated pseudoaneurysm: color Doppler showed the lesion as a small rounded area with whirling flow; spectral analysis allowed recognition of both the afferent artery with low impedance flow and the draining vein with pulsatile, arterialized flow. The second patient had a normal color Doppler study; however, spectral analysis demonstrated signals with low vascular impedance from an intra-parenchymal artery at the lower pole, and a jet of turbulent flow. Following disappearance of clinical findings, such Doppler abnormalities were no longer detectable. When a iatrogenic arteriovenous fistula is considered on clinical grounds, both color and Doppler spectral analysis of waveforms from intra-parenchymal vessels should be performed. Possibly, further advances in color Doppler technology will permit the use of this examination as the first imaging procedure in these clinical situations.Correspondence to: L. E. Derchi 相似文献
8.
脑动静脉畸形实验动物模型的建立 总被引:2,自引:0,他引:2
刘作勤 《中国介入影像与治疗学》2005,2(3):157-160
脑动静脉畸形(AVM)实验性动物模型建立是研究AVM必不可少的。建立脑AVM实验性动物模型最常用的动物是猪,目前主要有如下几种猪的脑AVM模型建立的方式:利用猪的自然奇网模式,颈动脉一颈内静脉瘘模式,奇网一海绵窦交通模式,利用导管形成AVM模型以及颈总动脉与颈外静脉端一端吻合模式。随着此项工作的不断完善,对脑AVM的病理生理、血流动力学的认识定会进一步提高,这将会更有力地有助于AVM的治疗。 相似文献
9.
B. Berthelsen 《European radiology》1992,2(5):452-458
The results of embolisation of dural arteriovenous fistulas draining into the transverse or sigmoid sinus were evaluated in 20 patients. Tinnitus was the main symptom in all patients although one also suffered from vertigo and sudden deafness. Nine patients were treated with PVA (polyvinylalcohol) alone and 11 with combined PVA and bucrylate (isobutyl-2-cyanoacrylate) in 1–9 procedures. Recurrence of symptoms, requiring repeated procedures was common but at subsequent clinical follow up 10 patients had no tinnitus, 5 were improved and only 5 experienced no change. Complications occured in six patients: four had transient neurological symptoms and one of these also developed a necrotic wound which later healed. One patient suffered from a cranial nerve palsy and one had an intracranial haemorrhage after a transvenous embolisation. This last patient recovered completely. The best clinical results were achieved in small fistulas and fistulas treated with combined bucrylate and PVA. 相似文献
10.
Ahmed M. Abu El-Asrar Eman S. Kahtani Khalid F. Tabbara 《Documenta ophthalmologica. Advances in ophthalmology》1995,89(4):313-320
In this report we describe, herewith, a patient with primary pigmentary dystrophy of the retina (retinitis pigmentosa) associated with unilateral retinal arteriovenous communication and exudative retinal detachment. The patient had complete resolution of the retinal detachment following laser photocoagulation treatment. Such association has not been previously reported. 相似文献