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排序方式: 共有198条查询结果,搜索用时 31 毫秒
1.
Edward A. Essock William K. Krebs James R. Prather 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1992,91(3):520-524
Summary The ability of humans to detect striated stimuli on the distal phalanges was found to be highly anisotropic. Observers were much more sensitive to stripes presented in the proximal-distal orientation than to stripes in any other orientation. This tactile anisotropy was contrasted with the well-known visual anisotropy in which sensitivity is greatest for stripes at the horizontal and vertical orientations. We suggest that both the tactile anisotropy and the visual anisotropy are caused by corresponding anisotropies in the distribution of preferred orientations of orientation-selective neurons with in the respective modalities. 相似文献
2.
The specific impedance of cardiac tissue cannot be measured directly. Instead, the investigator obtains voltage and current
measurements and places them into a model of the tissue's structure to infer the impedances of elements of the model. If the
model fails to describe major aspects of the real tissue, the results may be worthless, although possibly self-consistent.
In the literature of impedance measurement in cardiac tissue, only rarely is the model explicitly described; more commonly,
the tissue model is adopted implicitly when equations giving the impedance in terms of voltage and current measurements are
adopted. This paper examines the series of models that have been used in specific impedance measurements of cardiac tissue
and shows how the same or similar measurements can accurately describe tissue impedivity or can lead to significant errors
when inadequate models such as isotropic and anisotropic monodomains (although a part of work of historical merit) are used. 相似文献
3.
Microcracking in bone due to internal strains caused by mineralization is a possible mechanism of damage. Similar damage can be seen in other biological composites such as trees experiencing growth-related prestresses. Dimensional changes in cortical bone due to demineralization and experimental glycation were studied to test whether mineralization-related prestrains are consistent with observed microcracking patterns in bone. A microscopy technique that enables wet measurements of length and angle of milled bone specimens was used. Demineralization of bovine and human bones caused significant anisotropic changes in tissue size. Dimensional changes due to demineralization in bovine bone were prevented or reduced when collagen cross linking was increased by glycation. The dimensional changes of bone caused by demineralization are consistent with the hypothesis that mineralization-caused stresses in remodeling tissue can cause microcracks. © 2002 Biomedical Engineering Society.
PAC2002: 8719Rr 相似文献
4.
Dr. B. J. Roth 《Medical & biological engineering & computing》1989,27(5):491-495
Spatial and temporal frequency-dependent conductivities are used to interpret four-electrode conductivity measurements on
skeletal muscle. The model qualitatively explains the observed dependence of the experimental data on the temporal frequency
of the injected current, the angle between the electrode array and the fibre direction and the distance between the electrodes. 相似文献
5.
Hans Werner Weizsäcker 《Pflügers Archiv : European journal of physiology》1988,412(1-2):147-154
The quasistatic passive venous elastic properties were studied in-vitro on 6 cylindrical segments of abdominal vena cava from Wistar rats. Using noncontact methods of deformation measurement, diameters and axial force of the segments were analyzed as a function of simultaneous axial stretch and internal pressure in the physiological range of 0–2.7 kPa. The elasticity of the wall tissue was investigated in terms of moduli of elasticity in the circumferential, axial and radial direction. Results show that the pressure-diameter relationship is highly nonlinear, indicating that veins are extremely compliant at lowest pressures and rather stiff beginning from some 0.7 kPa of pressure. The axial force decreases with pressure at small prestretches, increases at large, but remains constant for the in-vivo prestretch. The venous wall tissue is markedly anisotropic in the entire physiological range of deformations. 相似文献
6.
Roth BJ 《Medical & biological engineering & computing》1999,37(4):523-525
If current is flowing in cardiac tissue, and if the myocardial fibres approach a sealed boundary at an angle, then the tissue within a few length constants of the boundary is polarised. This polarisation occurs when the cardiac tissue has different anisotropy ratios in the intracellular and extracellular spaces. This new mechanism of tissue polarisation is demonstrated using a simple, analytical model, and it is shown quantitatively that this polarisation can be nearly as large as that occurring near an electrode. 相似文献
7.
Christopher J. Moore Melissa C. Caughey Diane O. Meyer Regina Emmett Catherine Jacobs Manisha Chopra James F. Howard Caterina M. Gallippi 《Ultrasound in medicine & biology》2018,44(12):2519-2530
Our group has previously found that in silico, mechanical anisotropy may be interrogated by exciting transversely isotropic materials with geometrically asymmetric acoustic radiation force excitations and then monitoring the associated induced displacements in the region of excitation. We now translate acoustic radiation force-based anisotropy assessment to human muscle in vivo and investigate its clinical relevance to monitoring muscle degeneration in Duchenne muscular dystrophy (DMD). Clinical anisotropy assessments were performed using Viscoelastic Response ultrasound, with a degree of anisotropy reflected by the ratios of Viscoelastic Response relative elasticity (RE) or relative viscosity (RV) measured with the asymmetric radiation force oriented parallel versus perpendicular to muscle fiber alignment. In vivo results from rectus femoris and gastrocnemius muscles of boys aged ~7.9–10.4 y indicate that RE and RV anisotropy ratios in rectus femoris muscles of boys with DMD were significantly higher than those of healthy control boys (RE: DMD?=?1.51 ± 0.87, control?=?0.99 ± 0.69, p?=?0.04, Wilcoxon rank sum test; RV: DMD?=?1.04 ± 0.71, control?=?0.74 ± 0.22, p?=?0.02). In the gastrocnemius muscle, only the RV anisotropy ratio was significantly higher in dystrophic than control patients (DMD?=?1.23 ± 0.35, control?=?0.88 ± 0.31, p?=?0.04). In the dystrophic rectus femoris muscle, the RE anisotropy ratio was inversely correlated (slope?=?–0.03/lbf, r?=?–0.43, p?=?0.07, Pearson correlation) with quantitative muscle testing functional output measures but was not correlated with quantitative muscle testing in the dystrophic gastrocnemius. These results suggest that Viscoelastic Response RE and RV measures reflect differences in mechanical anisotropy associated with functional impairment with dystrophic degeneration that are relevant to monitoring DMD clinically. 相似文献
8.
Simulated body surface potential maps (SBSPM) with isotropic and anisotropic heart models were compared to investigate the effect of myocardial anisotropy on body surface electrocardiograms at a whole heart level. Rotative fiber orientations of total 90° was incorporated into an isotropic heart model. The anisotropy of conduction velocity and intracellular electric conductivity was included in the simulation. SBSPM based on epicardial, intramural, and endocardial stimulation show high correlation with fiber orientations. On the other hand, the anisotropy cannot be distinguished from the SBSPM in the simulation of normal heart model. 相似文献
9.
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