全文获取类型
收费全文 | 145209篇 |
免费 | 45770篇 |
国内免费 | 1511篇 |
专业分类
耳鼻咽喉 | 2073篇 |
儿科学 | 5568篇 |
妇产科学 | 855篇 |
基础医学 | 29535篇 |
口腔科学 | 9392篇 |
临床医学 | 18125篇 |
内科学 | 30449篇 |
皮肤病学 | 4956篇 |
神经病学 | 19648篇 |
特种医学 | 7590篇 |
外国民族医学 | 8篇 |
外科学 | 20031篇 |
综合类 | 4704篇 |
现状与发展 | 10篇 |
一般理论 | 8篇 |
预防医学 | 8882篇 |
眼科学 | 1862篇 |
药学 | 11571篇 |
10篇 | |
中国医学 | 2828篇 |
肿瘤学 | 14385篇 |
出版年
2024年 | 78篇 |
2023年 | 565篇 |
2022年 | 954篇 |
2021年 | 2683篇 |
2020年 | 7173篇 |
2019年 | 12392篇 |
2018年 | 11970篇 |
2017年 | 13175篇 |
2016年 | 12323篇 |
2015年 | 12299篇 |
2014年 | 13033篇 |
2013年 | 14123篇 |
2012年 | 12071篇 |
2011年 | 12267篇 |
2010年 | 10496篇 |
2009年 | 7072篇 |
2008年 | 7711篇 |
2007年 | 6151篇 |
2006年 | 5786篇 |
2005年 | 5451篇 |
2004年 | 5127篇 |
2003年 | 4599篇 |
2002年 | 4125篇 |
2001年 | 3282篇 |
2000年 | 1936篇 |
1999年 | 780篇 |
1998年 | 459篇 |
1997年 | 443篇 |
1996年 | 403篇 |
1995年 | 351篇 |
1994年 | 314篇 |
1993年 | 240篇 |
1992年 | 262篇 |
1991年 | 249篇 |
1990年 | 207篇 |
1989年 | 180篇 |
1988年 | 181篇 |
1987年 | 164篇 |
1986年 | 134篇 |
1985年 | 186篇 |
1984年 | 144篇 |
1983年 | 109篇 |
1982年 | 135篇 |
1981年 | 142篇 |
1980年 | 123篇 |
1979年 | 88篇 |
1978年 | 73篇 |
1977年 | 57篇 |
1976年 | 76篇 |
1975年 | 30篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
《Ultrasound in medicine & biology》2022,48(8):1361-1372
In recent years, thermal ablation has played an increasingly important role in treating various tumors in the clinic. A practical thermochromic phantom model can provide a favorable platform for clinical thermotherapy training of young physicians or calibration and optimization of thermal devices without risk to animals or human participants. To date, many tissue-mimicking thermal phantoms have been developed and are well liked, especially the polyacrylamide gel (PAG)–based phantoms. This review summarizes the PAG-based phantoms in the field of thermotherapy, details their advantages and disadvantages and provides a direction for further optimization. The relevant physical parameters (such as electrical, acoustic, and thermal properties) of these phantoms are also presented in this review, which can assist operators in a deeper understanding of these phantoms and selection of the proper recipes for phantom fabrication. 相似文献
3.
4.
5.
ObjectiveTo analyze the effects of electrolysis, through a medium frequency current, associated to aerobic physical activity in the body composition of young women.MethodsThe study was composed of 34 sedentary women (24.35 ± 4.43 years, 71.30 ± 7.08 kg, 1.61 ± 0.06 m, 27.31 ± 1.67 kg/m2) which were evaluated for their anthropometric measures and body composition. The volunteers were randomly assigned to two group: Electrolyphysis plus Aerobic Exercise (gEEA): 17 volunteers were submitted to the application, for 60 min , of the Aussie current, followed by aerobic physical activity (77% of HRmax) on the trampoline for 40 min, through video-lessons of Jump; and Aerobic Exercise group (gEA): 17 volunteers performed only physical activity following the same parameters mentioned above. Each group performed its protocols twice weekly, for 5 weeks, totaling 10 sessions. For the data analysis, measures repeated ANOVA was performed to compare the means of the variables analyzed before and after the treatment protocols using the SPSS - 21.0 software, adopting a p ≤ 0.05.ResultsAlthough gEEA decreased suprailiac skinfold (p = 0.04), abdominal skinfold (p = 0.03) and circumference at umbilical scar (p = 0.02) in an intragroup analysis, these means differences in anthropometric measures were not important between-groups (p > 0.05). Furthermore, there were no effect of treatment on body composition (p > 0.05).ConclusionTo this studied condition, our results suggested that application of medium frequency electrolysis did not enhance the losses on anthropometric measures and body composition. 相似文献
6.
Phoebe Hammer Kevin White Stephanie Mengden Vessy Korcheva Philipp W. Raess 《Journal of cutaneous pathology》2019,46(5):343-346
Cutaneous leiomyomas are rare benign smooth‐muscle tumors. These lesions are distinguished based on their cell of origin and are subclassified as pilar leiomyoma, angioleiomyoma, and genital‐type leiomyoma. Nipple leiomyoma is the least common genital‐type leiomyoma, arising from the dartoic muscle cell of the nipple. Histologic examination of the lesion is necessary for definitive diagnosis, and these uncommon tumors can pose a diagnostic challenge. We describe herein a series of six nipple leiomyomas with a spectrum of histologic appearances. 相似文献
7.
Keiko Goto Yutaka Fujiwara Takeshi Isobe Naoko Chayahara Naomi Kiyota Toru Mukohara Yukari Tsubata Takamasa Hotta Kenji Tamura Noboru Yamamoto Hironobu Minami 《Cancer science》2019,110(6):1987-1994
Although dose reduction of S‐1 is recommended for patients with impaired renal function, dose modification for such patients has not been prospectively evaluated. The aim of the present study was to investigate the pharmacokinetic parameters of 5‐fluorouracil, 5‐chloro‐2,4 dihydroxypyridine and oteracil potassium, and to review the recommended dose modification of S‐1 in patients with renal impairment. We classified patients receiving S‐1 into 4 groups according to their renal function, as measured using the Japanese estimated glomerular filtration rate (eGFR) equation. The daily S‐1 dose was adjusted based on the patient's eGFR and body surface area. Blood samples were collected for pharmacokinetic analysis. A total of 33 patients were enrolled and classified into 4 groups as follows: 10 patients in cohort 1 (eGFR ≥ 80 mL/min/1.73 m2), 10 patients in cohort 2 (eGFR = 50‐79 mL/min/1.73 m2), 10 patients in cohort 3 (eGFR = 30‐49 mL/min/1.73 m2), and 3 patients in cohort 4 (eGFR < 30 mL/min/1.73 m2). Those in cohorts 3 and 4 treated with an adjusted dose of S‐1 showed a similar area under the curve for 5‐fluorouracil (941.9 ± 275.6 and 1043.5 ± 224.8 ng/mL, respectively) compared with cohort 2 (1034.9 ± 414.3 ng/mL). Notably, while there was a statistically significant difference between cohort 1 (689.6 ± 208.8 ng/mL) and 2 (P = 0.0474) treated with an equal dose of S‐1, there was no significant difference observed in the toxicity profiles of the cohorts. In conclusion, dose adjustment of S‐1 in patients with impaired renal function using eGFR is appropriate and safe. 相似文献
8.
9.
10.
Daniel Schar Pawin Padungtod Nguyen Tung Michael OLeary Wantanee Kalpravidh Filip Claes 《Influenza and other respiratory viruses》2019,13(6):618-621
Among the chief limitations in achieving early detection and control of animal‐origin influenza of pandemic potential in high‐risk livestock populations is the existing lag time between sample collection and diagnostic result. Advances in molecular diagnostics are permitting deployment of affordable, rapid, highly sensitive, and specific point‐of‐capture assays, providing opportunities for targeted surveillance driving containment strategies with potentially compelling returns on investment. Interrupting disease transmission at source holds promise of disrupting cycles of animal‐origin influenza incursion to endemicity and limiting impact on animal production, food security, and public health. Adoption of new point‐of‐capture diagnostics should be undertaken in the context of promoting robust veterinary services systems and parallel support for operationalizing pre‐authorized plans and communication strategies that will ensure that the full potential of these new platforms is realized. 相似文献