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排序方式: 共有1225条查询结果,搜索用时 15 毫秒
1.
对某镍业公司车间空气中镍浓度和工人指甲镍含量进行了测定。按照生产过程和卫生学特点,将所获数据划分为碎矿压球、电炉转炉和汽车维修三组。空气镍浓度几何均值分别为0.0978、0.0623和0.0202mg/m~3;工人指甲镍几何均值分别为23.04、21.07和4.84μg/g;两者呈现一定的接触水平-反应关系。表明以指甲镍作为职业性接镍人群的生物监测指标有一定的参考价值。 相似文献
2.
$BasicCollegeofmedicalScienes;InstituteofEndemicDiseases 相似文献
3.
Patch testing was carried out in 851 atopic patients; 181 atopic dermatitis (AD) patients were additionally tested with 50% dilutions of the test substances. The occurrence of allergic and irritant reactions was frequent, being 57% and 33% for AD patients aged 28-41 years and 19-27 years, respectively. Among age-matched allergic rhinitis (AR)/allergic conjunctivitis (AC) or asthma (A) patients, the number of allergic reactions varied from 25 to 30%, and for irritant reactions was 24%. In all groups, nickel, fragrance-mix, balsam of Peru and neomycin were the commonest allergens. Contact allergy to ingredients of topical medicaments was common among AD patients and patients with severe and long-lasting dermatitis were most frequently sensitized. However, sensitivity to multiple substances was not common among those patients. The number of irritant reactions was considerable, but 50% dilution of the test substances did not solve the problem. 相似文献
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The histological distinction between carcinosarcoma and mesothelioma has received little attention. The object of this study was to describe the histology and immunohistochemistry of two carcinosarcomas presenting as pleural tumours. These were compared with 12 carcinosarcomas from sites within the lung, and with the established features of mesothelioma. Histologically and immunohistochemically, these 'pleural' carcinosarcomas are similar to conventional pulmonary carcinosarcomas but accurate recognition is hindered by their gross appearance and biphasic histology which closely mimic mesothelioma. They may exhibit features such as neutral mucin, expression of carcinoembryonic antigen, squamous differentiation, and neuroendocrine differentiation which, when present, are evidence against mesothelioma. These tumours are rare and have passed unnoticed until now. 相似文献
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二乙基二硫代氨基甲酸钠驱镍作用的实验研究 总被引:1,自引:0,他引:1
本文用大鼠研究了带-SH基的二乙基二硫代氨基甲酸钠(Dithiocarb,简称Na-DDC或称铜试剂)和不带-SH基的新螯合剂(H-73-10)的驱镍作用。结果表明,Na-DDC对羰基镍(Ni(CO)_4〕的驱镍作用明显优于H-73-10;与此相反,H-73-10对硝酸镍〔Ni(NO_3)_2〕染毒大鼠的驱镍作用却明显优于Na-DDC。 相似文献
8.
Augmentation of antigen-specific lymphoproliferative responses in vitro by biological response modifiers. 总被引:1,自引:0,他引:1 下载免费PDF全文
T D de Gruijl J J Moore E de Vries B M von Blomberg-van der Flier J C Fonk R J Scheper 《Clinical and experimental immunology》1994,96(3):535-540
The detection of antigen-specific T cell responsiveness, particularly of resting memory lymphocytes, in cultures of peripheral blood mononuclear cells (PBMC) may be hampered by a less than optimal antigen presentation in vitro. Augmented sensitivity of the test system may be achieved by the addition of reagents with a beneficial effect on lymphocyte and antigen-presenting cell (APC) functions. In this study the effect of several biological response modifiers on antigen-specific T cell proliferation was determined, using nickel sulphate and tetanus toxoid as test antigens. IL-1 alpha (100 U/ml), interferon-gamma (IFN-gamma) (10 U/ml), and indomethacin (2 microM) were found to significantly enhance nickel-induced proliferation in PBMC cultures from nickel-hypersensitive donors (n = 6). Tetanus-induced proliferation (n = 5) was similarly enhanced, both by the above supplements and by the addition of polyethylene glycol (PEG) or a neuraminidase treatment of the PBMC before culture. The addition to PBMC cultures of a combination of IL-1 alpha (30 U/ml), IFN-gamma (10 U/ml), and indomethacin (2 microM) is recommended to specifically enhance antigen-induced lymphoproliferative signals. 相似文献
9.
P. D. Pigatto E. Gibelli M. Fumagalli A. Bigardi M. Morelli G. F. Altomare 《Contact dermatitis》1990,22(1):27-31
In some cases that have been diagnosed as contact allergy to nickel, there are repeated cutaneous eruptions of pompholyx, even in areas with no direct contact with the metal. The possible alimentary origin of dyshidrotic eczema should be considered when deciding on therapy. We have collected the clinical data for 24 patients with dyshidrotic eczema caused by nickel, to evaluate the benefit of a low-nickel diet versus treatment with oral disodium cromoglycate, comparing both objective and subjective symptoms. A low-nickel diet does not improve these patients but those treated with DSCG reacted better, from both objective and subjective point of view, than either the controls or the patients treated by diet. We next did intestinal permeability tests before therapy and after 15 days of treatment. We found that nickel uptake diminishes simultaneously with the reduction of absorption through the smaller aqueous "pores". This phenomenon was greatest after DSCG. We suggest that DSCG can help selected cases of pompholyx. 相似文献
10.
钛镍记忆合金牵张器牵张增高牙槽嵴的动态研究 总被引:2,自引:0,他引:2
目的:通过对犬牵张手术后的下颌牙槽嵴高度、骨密度和组织学变化进行动态研究,了解应用钛镍记忆合金牵张器牵张成骨增高牙槽嵴的变化规律。方法:牵张增高牙槽嵴的15只犬于术前、术后1周、5周、3个月、6个月分别测量术区及对照侧相应位置颌骨高度,拍X线片,取牵张区及对照侧相同区域骨块进行双能X线骨密度测量并进行组织学研究。结果:牙槽嵴增高高度在牵张术后1、3、6个月分别减少5%、8%、11%。牵张术后3个月,牵张区骨密度低于对照侧;6个月,与对照侧的差异无显著性。结论:使用TiN i-SMA牵张器增高牙槽嵴成骨迅速,再吸收程度较低,成骨形态满意。牵张成的新骨有足够的强度,可以满足种植等后期修复的要求。 相似文献