全文获取类型
收费全文 | 5122篇 |
免费 | 248篇 |
国内免费 | 97篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 625篇 |
妇产科学 | 192篇 |
基础医学 | 1395篇 |
口腔科学 | 54篇 |
临床医学 | 435篇 |
内科学 | 469篇 |
皮肤病学 | 127篇 |
神经病学 | 686篇 |
特种医学 | 70篇 |
外科学 | 243篇 |
综合类 | 456篇 |
预防医学 | 324篇 |
眼科学 | 65篇 |
药学 | 200篇 |
1篇 | |
中国医学 | 68篇 |
肿瘤学 | 32篇 |
出版年
2023年 | 36篇 |
2022年 | 84篇 |
2021年 | 121篇 |
2020年 | 106篇 |
2019年 | 101篇 |
2018年 | 92篇 |
2017年 | 95篇 |
2016年 | 89篇 |
2015年 | 92篇 |
2014年 | 174篇 |
2013年 | 258篇 |
2012年 | 198篇 |
2011年 | 245篇 |
2010年 | 146篇 |
2009年 | 191篇 |
2008年 | 177篇 |
2007年 | 209篇 |
2006年 | 180篇 |
2005年 | 175篇 |
2004年 | 154篇 |
2003年 | 142篇 |
2002年 | 139篇 |
2001年 | 125篇 |
2000年 | 121篇 |
1999年 | 124篇 |
1998年 | 147篇 |
1997年 | 129篇 |
1996年 | 168篇 |
1995年 | 132篇 |
1994年 | 113篇 |
1993年 | 124篇 |
1992年 | 107篇 |
1991年 | 96篇 |
1990年 | 74篇 |
1989年 | 65篇 |
1988年 | 76篇 |
1987年 | 76篇 |
1986年 | 69篇 |
1985年 | 68篇 |
1984年 | 79篇 |
1983年 | 36篇 |
1982年 | 59篇 |
1981年 | 60篇 |
1980年 | 47篇 |
1979年 | 42篇 |
1978年 | 24篇 |
1977年 | 30篇 |
1976年 | 23篇 |
1975年 | 12篇 |
1971年 | 7篇 |
排序方式: 共有5467条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Takahiro Namiki Chika Takano Ryoji Aoki Quang Duy Trinh Ichiro Morioka Satoshi Hayakawa 《Congenital anomalies》2022,62(1):38-41
Congenital rubella syndrome (CRS) results from maternal rubella virus infection in early pregnancy. Abnormal neuroimaging findings have been analyzed in a small number of CRS patients in the past; however, their clinical significance has been poorly addressed. Therefore, we have investigated the neuroimaging findings of 31 patients with CRS from previous studies. The most common finding was parenchymal calcification, which was observed in 18 of 31 patients (58.1%). A multivariable logistic regression model showed that it was associated with psychomotor or mental retardation (p = 0.018), suggesting that parenchymal calcification in CRS could be a prognostic factor. 相似文献
5.
Bryan E.K. Guevara Suhail Saleem Wan‐Ting Chen Pa‐Fan Hsiao Yu‐Hung Wu 《Journal of cutaneous pathology》2019,46(5):347-352
Lucio phenomenon is an atypical reaction of leprosy, characterized by vasculitic lesions that can mimic antiphospholipid syndrome (APS) clinically. Distinguishing the two can be difficult as antiphospholipid autoantibodies may be present in patients with leprosy. We report on a 32‐year‐old female patient presenting with a sudden onset of fever, hemorrhagic bullae, and skin necrosis on her lower legs. She was treated for APS due to the presence of antiphospholipid antibodies but had an inadequate response. A skin biopsy revealed thrombotic vasculopathy and necrotizing vasculitis associated with aggregation of foam cells in the perivascular area and subcutis, with acid‐fast bacilli in the histiocytes and blood vessel walls. Direct immunofluorescence showed IgM, C3, and fibrinogen deposition in the superficial and deep dermal blood vessels. The pathology confirmed the diagnosis of Lucio phenomenon, and appropriate therapy was given. It is essential to evaluate the patient comprehensively, including clinical, serological, and pathological aspects, to obtain the correct diagnosis. 相似文献
6.
Convergent Reliability and Validity of the Questions About Behavioral Function and the Motivation Assessment Scale: A Replication Study 总被引:1,自引:1,他引:0
Karrie A. Shogren Johannes Rojahn 《Journal of developmental and physical disabilities》2003,15(4):367-375
This study compared key psychometric properties of the Motivation Assessment Scale (MAS) and the Questions About Behavioral Function (QABF) and explored their convergent validity. Twenty adults with mental retardation and problem behaviors (aggression, self-injury, or property destruction) and 31 respondents participated. Test–retest reliability of the subscales in both scales was good to excellent (Cicchetti, D. V., 1994, Psychol. Assess. 6: 284–290), and—except for 1 QABF subscale—internal consistency was good considering the small number of items and the purpose of the scale. Consistent with some earlier studies, interrater reliability was less satisfactory with both scales falling only into the fair to good range.Correlations between functionally equivalent subscales were statistically significant and were generally higher than correlations between nonequivalent subscales. The QABF and the MAS were found to be comparable in terms of the assessed reliabilities, and both instruments appear to be measuring very similar constructs. 相似文献
7.
M Ugras† G Kocak† H Ozcan‡ 《Journal of the European Academy of Dermatology and Venereology》2006,20(9):1126-1128
Neu-Laxova syndrome (NLS) is a rare autosomal recessive syndrome, characterized by severe intrauterine growth retardation (IUGR), microcephaly, abnormal brain development, oedema and ichthyosis. It was first reported in 1971 by Neu et al. (Pediatrics 47: 610-612) and since then no more than 60 cases have been reported. A newborn girl delivered from a 29-year-old healthy mother was admitted to hospital with a thick membrane covering her body and dismorphic appearance. The diagnosis of NLS was made according to characteristic features. The syndrome is known to have a poor prognosis and the baby lived for 9 weeks. This case is one of the longest living cases of NLS and the fourth case reported from Turkey. 相似文献
8.
冠状动脉瘘的诊治及新进展 总被引:2,自引:0,他引:2
冠状动脉瘘是一种罕见的冠状动脉畸形,绝大多数属于先天性畸形,极少数可由后天因素引起。由于冠状动脉血流向有关心腔、血管异常分流,导致引流部位负荷加重、瘘远端心肌缺血而引起相应临床症状。目前,绝大多数冠状动脉瘘已能由超声心动图明确诊断并可经内科介入技术或外科手术治愈。 相似文献
9.
Mikael Hellström Bo Jacobsson Ulf Jodal Jan Winberg Anders Odén 《Pediatric nephrology (Berlin, Germany)》1987,1(3):269-275
This study presents the result of 12–21 years' follow-up in a group of children with neonatal urinary tract infection (onset within 1 month after birth) in whom early renal growth retardation was noted without concomitant classical renal scarring. In all cases the neonatal infection was diagnosed and treated within a few days of onset and the patients were closely supervised thereafter. Renal length, parenchymal thickness and area were measured at urography. At first follow-up (22 children, mean age 4.1 years) a significant reduction of renal parenchymal thickness was noted. Long-term follow-up (18 patients, mean age 17 years) demonstrated a normalization of renal size in the entire group, although less complete in the subgroup with reflux. There were two major findings in the present study. Firstly, renal growth retardation was seen after neonatal infection, both with and without reflux. Secondly, normalization of renal size in previously small kidneys was demonstrated, suggesting that growth retardation can be a reversible phenomenon. The tendency for such normalization was slightly more marked in children without reflux. Reduction of parenchymal thickness without calyceal deformity, therefore, does not necessarily mean irreversible damage, and differentiation between permanent scarring and temporary growth retardation can thus only be made at later follow-up, possibly not until after puberty. The demonstration of renal growth retardation in spite of early diagnosis and treatment emphasizes the great vulnerability of the kidney in the newborn. 相似文献
10.
A boy with rhizomelic chondrodysplasia punctata, diagnosed on the laboratory evidence of a high plasma concentration of phytanic
acid and a low erythrocyte concentration of plasmalogens, has been followed from birth to the age of 16 years. The clinical
pattern (somatic, skeletal and neurological) tallies with published findings in this disease. Unusual findings are the associated
epilepsy, confirmed by EEG, and the long survival. CT brain scan and MRI showed cortical and subcortical atrophy but not gyral
abnormalities or demyelination.
Sommario Viene descritto il caso di un bambino affetto da condrodisplasia punctata rizomelica seguito dalla nascita fino ai 16 anni. La diagnosi clinica, efettuata in base alle caratteristiche somatiche, scheletriche e neurologiche del paziente è stata confermata dai reperti di laboratorio (alta concentrazione plasmatica di acido fitanico, bassa concentrazione di plasmalogeni eritrocitari). Come correlati inusuali del quadro clinico vanno segnalati l'associazione con epilessia e a la lunga sopravvivenza. La TAC e la RNM cerebrale hannovaltresì documentato atrofia corticale e sottocorticale ma non anomalie della girazione o demielinizzazione.相似文献