全文获取类型
收费全文 | 5780篇 |
免费 | 645篇 |
国内免费 | 226篇 |
专业分类
耳鼻咽喉 | 54篇 |
儿科学 | 90篇 |
妇产科学 | 94篇 |
基础医学 | 519篇 |
口腔科学 | 207篇 |
临床医学 | 675篇 |
内科学 | 645篇 |
皮肤病学 | 72篇 |
神经病学 | 333篇 |
特种医学 | 132篇 |
外国民族医学 | 4篇 |
外科学 | 458篇 |
综合类 | 1074篇 |
现状与发展 | 1篇 |
预防医学 | 749篇 |
眼科学 | 136篇 |
药学 | 455篇 |
9篇 | |
中国医学 | 361篇 |
肿瘤学 | 583篇 |
出版年
2024年 | 29篇 |
2023年 | 165篇 |
2022年 | 270篇 |
2021年 | 313篇 |
2020年 | 295篇 |
2019年 | 235篇 |
2018年 | 226篇 |
2017年 | 272篇 |
2016年 | 267篇 |
2015年 | 247篇 |
2014年 | 402篇 |
2013年 | 453篇 |
2012年 | 353篇 |
2011年 | 365篇 |
2010年 | 305篇 |
2009年 | 286篇 |
2008年 | 239篇 |
2007年 | 242篇 |
2006年 | 244篇 |
2005年 | 202篇 |
2004年 | 142篇 |
2003年 | 133篇 |
2002年 | 116篇 |
2001年 | 113篇 |
2000年 | 98篇 |
1999年 | 77篇 |
1998年 | 62篇 |
1997年 | 73篇 |
1996年 | 40篇 |
1995年 | 47篇 |
1994年 | 43篇 |
1993年 | 26篇 |
1992年 | 39篇 |
1991年 | 19篇 |
1990年 | 24篇 |
1989年 | 19篇 |
1988年 | 26篇 |
1987年 | 9篇 |
1986年 | 20篇 |
1985年 | 17篇 |
1984年 | 17篇 |
1983年 | 9篇 |
1982年 | 9篇 |
1981年 | 14篇 |
1980年 | 13篇 |
1979年 | 8篇 |
1978年 | 7篇 |
1977年 | 6篇 |
1976年 | 4篇 |
1975年 | 5篇 |
排序方式: 共有6651条查询结果,搜索用时 15 毫秒
1.
从污水处理厂活性污泥中筛选出1株有絮凝活性的细菌Z-052,经分子生物学鉴定为Di-aphorobacter属。对Z-052产絮凝剂的发酵条件进行了优化。研究结果表明,在优化培养基中,于30℃培养72h,其发酵液对4g/L高岭土悬液的絮凝活性可达93.2%。Z-052絮凝剂对活性炭、土壤、酵母等固体颗粒悬液的絮凝活性分别达到95.1%、80.4%和72.4%。 相似文献
2.
3.
Pathologic laughter and crying in ALS: a search for their origin 总被引:3,自引:0,他引:3
J. P. Gallagher 《Acta neurologica Scandinavica》1989,80(2):114-117
Spells of laughter and crying are well known in patients with amyotrophic lateral sclerosis (ALS). Since ALS occurs mostly in older age groups, this brings up the possibility that aging changes in the brain could play a causative role in the origin of such spells. To rule out or at least reduce the complicating factor of aging, a study was made of the incidence of pathologic laughter and crying in patients whose motor neuron disease had started before the age of 45 years. The data were collected from 73 such individuals, all with confirmed ALS. All told, 36 had experienced episodes of pathologic laughter and/or crying. Of these, 20 had bouts of both laughter and crying. 9 bouts of crying alone and 7 spells of laughter alone. Nearly all with such emotional spells had developed bulbar involvement with the illness. The youngest patient with spells was 31 when his illness began and 35 when he started to have bouts of crying. 相似文献
4.
乳腺癌新辅助化疗后动态增强MRI表现与病理反应性相关性研究 总被引:3,自引:0,他引:3
目的探讨乳腺癌新辅助化疗后动态增强MRI(DCE—MRI)表现的形态学和时间信号强度曲线(TIC)类型与病理学反应性的关系。方法45例乳腺癌患者经新辅助化疗结束后行乳腺DCE—MR检查及手术治疗。应用AW4.2图像工作站观察残余肿瘤强化的形态和TIC类型(共3型)。由病理科医师对乳腺癌化疗后手术标本的病理反应性进行评估,分为1~5级,5级为病理完全缓解,4级和5级为组织学显著反应。分析病理反应性级别与DCE—MRI残余强化的TIC类型、形态的关系,统计方法采用精确概率法。结果45例中病理反应性5级7例,4级16例,3级16例,1和2级共6例。20例I型曲线中组织学显著反应者占70.0%(14/20),而6例Ⅲ型曲线均为组织学反应不显著者。TIC类型在不同的病理反应级别分布差异有统计学意义(P=0.001)。组织学显著反应且有残余强化者共18例,其中非肿块性强化11例。残余强化的肿块(非肿块)形态表现在不同病理反应性分级中分布差异有统计学意义(P=0.012)。结论乳腺癌新辅助化疗后DCE—MRI的形态及血液动力学表现特点与化疗后病理反应性相关。非肿块性强化和I型TIC与组织学显著反应有关。 相似文献
5.
A. C. T. Huizinga R. H. G. Vandenbrom J. M. K. H. Wierda M.D. Ph.D. F. D. M. Hommes P. J. Hennis 《Acta anaesthesiologica Scandinavica》1992,36(5):463-468
The intubating conditions and neuromuscular blocking profile following 600 micrograms.kg-1 rocuronium (Org 9426) have been investigated in patients under various experimental conditions. They were compared with conditions following 1.5 mg.kg-1 suxamethonium, preceded by a precurarising dose (10 mg) of gallamine, and with those in a control group in the absence of a muscle relaxant. Rocuronium produced good to excellent intubating conditions at 60 as well as at 90 s after administration, even though there was only a partial blockade of the adductor pollicis muscle. Intubating conditions following suxamethonium were comparable with those after rocuronium. Half of the control patients could be intubated. The clinical duration and the recovery time of 600 micrograms.kg-1 of rocuronium were 24(4) and 9(3) min (mean(s.d.)), respectively. Rocuronium may have a major advantage over existing non-depolarising muscle relaxants due to the early presence of excellent intubating conditions. The results indicate that rocuronium may replace suxamethonium in procedures in which rapid sequence induction is required. 相似文献
6.
There is a scarcity of well-controlled studies of the seasonal variation in circadian rhythmicity. In the present study, the circadian phase of rectal temperature and the onset of slow wave sleep were studied in a series of twelve 24-h experiments, one each month of the year, for six healthy subjects under controlled conditions in a climatic chamber. In winter, as compared with summer, the average circadian rhythm of rectal temperature was phase delayed by 45 min, and the average onset of slow wave sleep was phase delayed by 40 min. The temporal relationship between the circadian phase of rectal temperature and the timing of slow wave sleep was maintained throughout the year. Habitual rising and retiring times covaried as well. Furthermore, the circadian rhythm of rectal temperature followed the timing of the photoperiod across the year, but had a much smaller range of seasonal variation. Apparently, the seasonal variation in the photoperiodic zeitgeber is largely compensated for by the stabilizing influence of secondary zeitgebers. However, in healthy subjects some effect of photoperiodic variation can still be observed. 相似文献
7.
对60例病毒性肝炎患者进行肝穿刺活检,结果发现,临床与病理诊断的符合率为46.6%,其中,急性肝炎的诊断符合率最低(23.8%),慢性迁延型肝炎(慢迁肝)为44.8%;HBsAg阳性首次发病的患者中,急性乙型肝炎仅为11.2%(2/18);临床诊断的慢性活动型肝炎(慢活肝)仅为病理检出的25.7%(9/35);肝炎患者中脾肿大,凝血酶元时间延长、A/G值<1.2、抗HBcIgM阳性可作为慢活肝与慢迁肝鉴别的重要指标。这些对提高病毒性肝炎临床分型诊断的准确率及指导临床治疗有意义。 相似文献
8.
毕新生 《右江民族医学院学报》1994,16(2):32-34
对28例青年人胃癌的临床及病理分析结果表明,其发病具有症状隐匿、病程短、进展快的特点,本组病例从出现症状到漏诊在6个月内为57.1%(16例),首发症状以上腹部疼痛、吐血、黑便多见,病理特征以结节蕈伞型、高分化腺癌多见。 相似文献
9.
10.
Abstract: This article integrates theory and research related to boundary ambiguity in parents of children with a chronic health condition. We propose that boundary ambiguity is a risk factor for psychological distress in these parents. Clinical applications and a case example highlight how boundary ambiguity can be assessed and managed in clinical settings by professionals working with parents with chronically ill children. Questions are provided for assessing boundary ambiguity in clinical and research settings, and implications for research are discussed. 相似文献