排序方式： 共有64条查询结果，搜索用时 312 毫秒
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Tadech Boonpiyathad Willem van de Veen Oliver Wirz Milena Sokolowska Beate Rückert Ge Tan Atik Sangasapaviliya Panitan Pradubpongsa Rattanaporn Fuengthong Pattarawat Thantiworasit Sunee Sirivichayakul Kiat Ruxrungtham Cezmi A. Akdis Mübeccel Akdis 《The Journal of allergy and clinical immunology》2019,143(3):1077-1086.e10
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Zuochen Du Anwei Chen Lu Huang Xin Dai Qiuyue Chen Di Yang Liling Li Heather Miller Lisa Westerberg Yuan Ding Xuemei Tang Masato Kubo Liping Jiang Xiaodong Zhao Hua Wang Chaohong Liu 《The Journal of allergy and clinical immunology》2021,147(5):1907-1923.e6
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Jehane Fadlallah Delphine Sterlin Claire Fieschi Christophe Parizot Karim Dorgham Hela El Kafsi Gaëlle Autaa Pascale Ghillani-Dalbin Catherine Juste Patricia Lepage Marion Malphettes Lionel Galicier David Boutboul Karine Clément Sébastien André Florian Marquet Christophe Tresallet Alexis Mathian Guy Gorochov 《The Journal of allergy and clinical immunology》2019,143(4):1575-1585.e4
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R-藻红蛋白介导的光敏反应诱导小鼠S180细胞凋亡的研究 总被引：3，自引：0，他引：3
目的：探讨R-藻红蛋白介导的光敏反应诱导的肿瘤细胞凋亡。方法：对培养的小鼠S180瘤细胞进行光动力治疗处理，通过观察DNA Ladders的形成和流式细胞仪分析，判断凋亡的发生与否。结果：光动力治疗处理一定时间后，S180瘤细胞出现凋亡，伴有特征性的DNA Ladders出现，同时流式细胞分析可得到相应的结果。结论：藻红蛋白是一种很有前景的光动力药物，其介导的光敏反应杀伤肿瘤细胞与诱导肿瘤细胞凋亡有关。 相似文献
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Famke L. Schneiders Charlotte M. Huijts Martine Reijm Hetty J. Bontkes Henk M.W. Verheul Tanja D. de Gruijl Hans J. van der Vliet 《Immunobiology》2018,223(2):171-177
Aminobisphosphonates (NBP) are used for treatment of metastatic bone disease. Frequently, patients undergoing NBP-treatment experience side-effects, known as acute phase response (APR), resulting from cytokine production by Vγ9Vδ2-T cells. As opposed to NBP, statins reduce intracellular phosphoantigen levels and prevent NBP-induced Vγ9Vδ2-T cell activation in vitro. We conducted a pilot study in patients with (bone-)metastasized malignancies receiving NBP-treatment and evaluated the phenotype and function of circulating Vγ9Vδ2-T cells in vivo and the effects of statins on Vγ9Vδ2-T cell responses and the associated APR. We observed reduced expression of perforin, granzyme B and HLA-DR on Vγ9Vδ2-T cells in patients treated with NBP and statins. However, statins could not prevent NBP-induced changes in circulating Vγ9Vδ2-T cell numbers or production of IFNγ and TNFα. Consistent with this, simvastatin could not prevent the occurrence of APR upon NBP-infusion. These observations call for the exploration of alternative strategies to prevent collateral APR upon NBP treatment. 相似文献
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《The Journal of allergy and clinical immunology》2019,143(6):2202-2214.e5
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