慢性结肠炎等疾病患者的大便异常与结肠电频谱改变

为探讨慢性结肠炎等疾病患者的大便异常与结肠电频谱改变的关系,对１１４例患者临床观察发现,消化道疾病患者有大便异常或倾向的比率颇高,所占比率从高至低依次为慢性结肠炎（ＣＳ,８０．０％）〉＋二指肠溃疡（ＤＵ,６９．２％）及十二指肠炎（ＤＳ;６８．７％）〉慢性胃炎（ＧＳ,５４．８％）。ＣＳ组有腹泻倾向者占５６．０％,便秘占２４．０％;ＤＳ组便烂便频者亦占４３．８％,都是明显高于ＧＳ组及对照组。     

Prevalence of Upper Gastrointestinal Lesions and Helicobacter pylori Infection in Crohn's Disease

Crohn's disease can affect the upper gut withreported variable frequency, although concurrentHelicobacter pylori infection has been reported to below. We prospectively investigated the prevalence of esophageal, gastric, and duodenal lesions andHelicobacter pylori infection in 67 Crohn's disease, 41ulcerative colitis patients, and 43 controls. Symptoms,esophagogastroduodenoscopy, and multiple biopsies were performed on all patients consecutively.Endoscopic lesions were found in 63% of Crohn's diseasepatients, with a Helicobacter pylori prevalence of 28%. Granulomas were found in three patients. Twenty-two percent of the ulcerative colitis patients hadlesions, with a 29% prevalence of Helicobacter pyloriinfection. Half of the controls had pathologicalendoscopy, and Helicobacter pylori was positive in 40% of the cases. Subjective symptoms did notpredict the presence of endoscopic lesions orHelicobacter pylori infection in inflammatory boweldisease patients. Chronic gastritis and duodenitis arecommon in Crohn's disease patients, and the majorityare not associated with Helicobacter pyloriinfection.