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1.
膨润土对药用混悬液助悬性能的考察 总被引:9,自引:1,他引:8
本文报道了无机胶体膨润土(Bentonite)作为助悬剂在炉甘石洗剂中的应用,并与有机助悬剂及另一种无机胶体XVT—M进行比较,显示了其优异的助悬性能。 相似文献
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乳舒胶囊镇痛、抗炎作用研究 总被引:2,自引:0,他引:2
目的:研究乳舒胶囊(RS)的镇痛、抗炎药效。方法:采用RS灌胃给药后,分别用甩尾法、热板法、扭体法研究RS对乳腺增生模型大鼠及小鼠的镇痛作用,分别用二甲苯法、琼脂法研究RS抑制小鼠耳廓炎症及大鼠慢性炎症性肉芽肿的作用。结果:乳舒胶囊能提高乳腺增生模型大鼠和小鼠的痛阈值、能减少醋酸致扭体疼痛小鼠的扭体次数、延长其发生扭体的潜伏期,有明显的镇痛作用;还可以抑制琼脂所致的大鼠肉芽肿和二甲苯致小鼠耳肿胀,有明显的抗炎作用。结论:乳舒胶囊镇痛、抗炎作用明显、疗效确切。 相似文献
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小叶锦鸡儿的药理作用 总被引:8,自引:0,他引:8
小叶锦鸡儿1g/kg,0.5g/kg灌胃给药明显地提高小鼠热痛阈(P<0.001),减少酒石酸锑钾所致的小鼠扭体反应次数(P<0.01),对抗二甲苯所致小鼠耳壳炎症(P<0.01),抑制蛋白加热变性(P<0.01),明显地降低氯仿诱发的小鼠室颤发生率。 相似文献
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P. J. N. Bloem L. M. G. C. Goessens P. Zamparo M. Sacher R. Paviotti P. E. di Prampero 《European journal of applied physiology》1991,62(3):204-210
Summary Thirteen male subjects performed a running test on the treadmill consisting of four standard exercise intensities [65%, 75%, 85%, 95% maximal O2 uptake (VO2max)] presented in ascending, descending or random order. At the end of each exercise intensity, O2 consumption, heart rate (f
c), venous blood lactate concentration ([la]b) and perceived exertion were assessed. This last variable was determined according to the Borg nonlinear CR-20 scale. The same variables were also determined during exercise at a standard intensity (65% or 95%VO2max) performed before and after a Finnish sauna bath. Ratings of perceived exertion showed a good test-retest reliability (r=0.77); they were the same when the exercise intensity was expressed in relative (%VO2max) or absolute (speed) terms, and were independent of the order of presentation of the exercise. The latter had no effect onf
c either but it did, however, influence [la]b, which was significantly higher in the descending, as compared to the ascending or random modes of presentation. The sauna bath increasedf
c at a given exercise intensity, but left perceived exertion and [la]b unchanged. It was concluded that at least under the present experimental conditions,f
c and venous [la]b do not play a major role as determinants of perceived exertion. 相似文献
7.
There is persuasive epidemiological and experimental evidence that dietary polyphenols have anti-inflammatory activity. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have long been used to combat inflammation. Recently, cyclooxygenase (COX) inhibitors have been developed and recommended for treatment of rheumatoid arthritis (RA) and osteoarthritis (OA). However, two COX inhibitors have been withdrawn from the market due to unexpected side effects. Because conventional therapeutic and surgical approaches have not been able to fully control the incidence and outcome of many inflammatory diseases, there is an urgent need to find safer compounds and to develop mechanism-based approaches for the management of these diseases. Polyphenols are found in many dietary plant products, including fruits, vegetables, beverages, herbs, and spices. Several of these compounds have been found to inhibit the inflammation process as well as tumorigenesis in experimental animals; they can also exhibit potent biological properties. In addition, epidemiological studies have indicated that populations who consume foods rich in specific polyphenols have lower incidences of inflammatory disease. This paper provides an overview of the research approaches that can be used to unravel the biology and health effects of polyphenols. Polyphenols have diverse biological effects, however, this review will focus on some of the pivotal molecular targets that directly affect the inflammation process. 相似文献
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红毛五加药理作用研究进展 总被引:15,自引:0,他引:15
目的对红毛五加药理作用研究进展进行全面综述。方法根据相关文献 ,按照药理作用分类汇总。结果红毛五加具有抗肿瘤、抗炎、抗病毒、保肝、镇痛、增强免疫功能等作用。结论红毛五加具有很强的药用开发潜力 相似文献
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