全文获取类型
收费全文 | 2976篇 |
免费 | 116篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 156篇 |
妇产科学 | 125篇 |
基础医学 | 125篇 |
口腔科学 | 13篇 |
临床医学 | 596篇 |
内科学 | 875篇 |
皮肤病学 | 13篇 |
神经病学 | 51篇 |
特种医学 | 141篇 |
外科学 | 586篇 |
综合类 | 207篇 |
预防医学 | 40篇 |
眼科学 | 36篇 |
药学 | 87篇 |
中国医学 | 26篇 |
肿瘤学 | 26篇 |
出版年
2024年 | 3篇 |
2023年 | 20篇 |
2022年 | 83篇 |
2021年 | 81篇 |
2020年 | 88篇 |
2019年 | 232篇 |
2018年 | 260篇 |
2017年 | 90篇 |
2016年 | 51篇 |
2015年 | 67篇 |
2014年 | 336篇 |
2013年 | 199篇 |
2012年 | 115篇 |
2011年 | 155篇 |
2010年 | 125篇 |
2009年 | 143篇 |
2008年 | 189篇 |
2007年 | 195篇 |
2006年 | 112篇 |
2005年 | 97篇 |
2004年 | 75篇 |
2003年 | 60篇 |
2002年 | 47篇 |
2001年 | 27篇 |
2000年 | 29篇 |
1999年 | 21篇 |
1998年 | 18篇 |
1997年 | 17篇 |
1996年 | 21篇 |
1995年 | 9篇 |
1994年 | 16篇 |
1993年 | 16篇 |
1992年 | 12篇 |
1991年 | 10篇 |
1990年 | 3篇 |
1989年 | 7篇 |
1988年 | 10篇 |
1987年 | 11篇 |
1986年 | 6篇 |
1985年 | 10篇 |
1984年 | 13篇 |
1983年 | 5篇 |
1982年 | 7篇 |
1981年 | 2篇 |
1980年 | 3篇 |
1979年 | 3篇 |
1978年 | 5篇 |
1976年 | 2篇 |
1975年 | 1篇 |
1974年 | 1篇 |
排序方式: 共有3109条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
《Journal of prosthodontic research》2020,64(2):167-174
PurposeFew investigations have examined the production of single restorations using intraoral scanners (IOS). Data on full-arch scans are rare, and data regarding torsion within the entire arch are very sparsely reported. Therefore, the aim of this study was to examine the deviations of torsion and linear distances in full-arch scans of three IOS based on different scanning principles.MethodsA cobalt-chrome-molybdenum alloy master model (CCMM) with four hemispheres was fabricated by laser sintering. The CCMM was digitized using a laboratory scanner (ATOS-Core/GOM) and scanned with three IOS (Omnicam/Sirona(OC); True Definition/3M(TD); TriosII/Cara-Version/Kulzer(TR)). All scan data were exported in a standard STL-file format and were analyzed with GOM Inspect software (V7.5/GOM). Torsion between the right and left side of the arch and linear accuracy (trueness and precision) were evaluated. After normality was confirmed, all data were subjected to parametric statistical analyses.ResultsThe torsion ranged from 0.07 ± 0.03°(OC) to 0.29 ± 0.14°(TD). Pairwise comparisons showed significant differences between the OC and TD scanners and between the TR and TD scanners. The linear distances ranged from 6 ± 5 μm(OC) to 298 ± 317 μm(TD). Significant differences were observed among all investigated IOS (p = 0.05).ConclusionsAlthough the highest torsion was observed for the TD scanner, it is still not clear whether the differences between the IOS are related to the scanning principle or to the scanning algorithm. Due to the high clinical relevance of full-arch restorations, future studies should consider torsion. Regarding linear accuracy, no general difference related to the scanning principles of the IOSs was observed. 相似文献
5.
6.
7.
Roberto V.P. Ribeiro Mitesh V. Badiwala Danny Ramzy Laura C. Tumiati Vivek Rao 《The Journal of thoracic and cardiovascular surgery》2019,157(2):615-625.e1
Objective
Hypertonic saline (HTS) has potent immune and vascular effects. We assessed recipient pretreatment with HTS on allograft function in a porcine model of heart transplantation and hypothesized that HTS infusion would limit endothelial and left ventricular (LV) dysfunction following transplantation.Methods
Heart transplants were performed after 6 hours of cold ischemic storage. Recipient pigs were randomized to treatment with or without HTS (7.5% NaCl) before cardiopulmonary bypass (CPB). Using a myograft apparatus, coronary artery endothelial-dependent (Edep) and -independent (Eind) relaxation was assessed. LV performance was determined using pressure-volume loop analysis. Pulmonary interleukin (IL)-2, IL-6, and tumor necrosis factor (TNF)-α expression was measured.Results
Weaning from CPB and LV performance after transplantation were improved in HTS-treated animals. Successful weaning from CPB was greater in the HTS-treated hearts (8 of 8 vs 2 of 8; P < .05). Mean LV functional recovery was improved in the HTS-treated animals, as assessed by preload recruitable stroke work (65 ± 10% vs 27 ± 10%; P < .001) and end-systolic elastance (55 ± 7% vs 37 ± 4%; P < .001). Treatment with HTS resulted in improved Edep (mean maximum elastance [Emax], 56 ± 5% vs 37 ± 7%; P < .001) and Eind (mean Emax%, 77 ± 6% vs 52 ± 4%; P < .001) vasorelaxation compared with control. Pulmonary expression of IL-2, IL-6, and TNF-α increased following transplantation, whereas HTS therapy attenuated IL production (P < .001). Transplantation increased plasma TNF-α levels and LV TNF-α expression, whereas HTS prevented this up-regulation (P < .001).Conclusions
Recipient HTS pretreatment preserves allograft vasomotor and LV function, and HTS therapy limits CPB-induced injury. HTS may be a novel recipient intervention to prevent graft dysfunction. 相似文献8.
9.
10.
Lobar torsion is reported as very rare but sometimes catastrophic complication if overlooked during the early postoperative period following a lobectomy, though it is totally preventable. In this novel technique, a piece of parietal pleural flap is harvested from the posterior wall of the chest using a hook diathermy while keeping its upper border as close to the apex as possible. Finally, distal end of the flap is secured to the upper edge of the lobe using a fine monofilament absorbable suture. This procedure not only protects the lobe from rotation but also maintains continuous expansion of the lung in the early postoperative period and may, therefore, be a good option to prevent such a serious complication in selected patients following a lobectomy. 相似文献