全文获取类型
收费全文 | 867篇 |
免费 | 41篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 3篇 |
妇产科学 | 5篇 |
基础医学 | 99篇 |
口腔科学 | 38篇 |
临床医学 | 88篇 |
内科学 | 81篇 |
皮肤病学 | 11篇 |
神经病学 | 15篇 |
特种医学 | 53篇 |
外科学 | 237篇 |
综合类 | 124篇 |
预防医学 | 40篇 |
眼科学 | 8篇 |
药学 | 51篇 |
1篇 | |
中国医学 | 54篇 |
肿瘤学 | 4篇 |
出版年
2024年 | 1篇 |
2023年 | 19篇 |
2022年 | 18篇 |
2021年 | 22篇 |
2020年 | 28篇 |
2019年 | 30篇 |
2018年 | 21篇 |
2017年 | 21篇 |
2016年 | 29篇 |
2015年 | 46篇 |
2014年 | 64篇 |
2013年 | 73篇 |
2012年 | 61篇 |
2011年 | 64篇 |
2010年 | 47篇 |
2009年 | 40篇 |
2008年 | 57篇 |
2007年 | 40篇 |
2006年 | 25篇 |
2005年 | 27篇 |
2004年 | 26篇 |
2003年 | 19篇 |
2002年 | 20篇 |
2001年 | 15篇 |
2000年 | 10篇 |
1999年 | 14篇 |
1998年 | 8篇 |
1997年 | 14篇 |
1996年 | 7篇 |
1995年 | 5篇 |
1994年 | 5篇 |
1993年 | 4篇 |
1992年 | 6篇 |
1991年 | 4篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1988年 | 2篇 |
1987年 | 6篇 |
1986年 | 6篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 2篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1977年 | 2篇 |
1972年 | 1篇 |
1968年 | 1篇 |
排序方式: 共有921条查询结果,搜索用时 15 毫秒
1.
目的:本研究采用多济敷外用于面部皮损磨削术后创面,观察其对创面愈合时间、皮肤色素沉着等的变化。方法:采用区域神经阻滞或局部浸润麻醉,对不同类型的面部皮损34例进行皮肤磨削治疗,术后创面应用多济敷或凡士林纱布作为底层敷料包扎创面,术后换药一次,保留底层敷料。结果:2001年8月至2003年9月间,通过自身对照,34例面部磨削术后采用多济敷治疗组较凡士林纱布组创面愈合时间缩短(P<0.05),经过6个月至2年的随访,皮肤色素沉着也有明显改善。结论:多济敷有利于缩短面部磨削术后创面愈合时间,改善面部色素沉着,外观满意。 相似文献
2.
为探讨无名异接骨冲剂加速骨折愈合的作用机理,选用55只新西兰大白兔,随机选择5只作为正常组;另50只在无菌条件下造成双桡骨标准骨折模型。将50只骨折兔随机平均分为实验组和对照组,实验组用无名异接骨冲剂每天4g/kg溶于20ml蒸馏水中分早晚两次灌胃;对照组用20ml蒸馏水灌胃。于骨折后第1,2,3,4及5周用断颈法每次每组处死5只兔,取骨痂进行抗骨形态发生蛋白(BMP)单克隆抗体免疫组化染色,并用CMIAS型图像分析仪对BMP含量进行定量分析。结果发现:实验组骨折局部BMP含量明显高于正常组(P<0.01);第1,2周实验组明显高于对照组(P<0.01);实验组BMP高峰出现在第2周,而对照组出现在第3周。认为,无名异接骨冲剂能促进成骨细胞合成BMP,使BMP峰值提前,从而加速骨折愈合。 相似文献
3.
Lyall A. J. Higginson Edward M. Farrell Virginia M. Walley Rodrick S. Taylor Wilbert J. Keon 《Lasers in medical science》1989,4(2):85-92
Injury associated with laser-induced tissue ablation may be reduced by using pulsed energy delivery at low repetition rates, as opposed to using continuous wave energy delivery. This study was designed to examine the similarities and differences between these two systems as regards the healing process, and to examine whether one is superior to the other. In order to test this postulate, the healing response of normal and atherosclerotic aorta were examined after exposure in vivo to argon and excimer (XeCl 308 nm) laser radiation in hypercholesterolemic swine. Swine were fed hyperlipidemic diets for eight months following balloon denudation of the descending aorta. Following general anaesthetic, the descending aorta was isolated and laser burns were made on both normal and atherosclerotic intima using a continuous wave argon laser delivered through a 50 diameter quartz fibre, and a XeCl excimer laser carried through a 1 mm diameter fibre. Energy levels of 3 to 5 J were applied with the argon laser. The pulse duration for the excimer laser was 30 ns and craters were produced using 10 to 60 pulses at a repetition rate of 20 Hz and an energy density of 2 J cm–2.Forty-eight hours after laser application, craters created by both lasers were filled with thrombus material. Argon burns were surrounded by thermal and acoustic injury which was not seen with excimer burns. Three weeks after laser application all crater surfaces were reconstituted. Unlike the excimer burns, argon craters demonstrated necrosis well beyond the crater margins and were characterized by multinucleate giant-cell reaction surrounding char debris. By nine weeks both excimer and argon laser burns were covered by fibrous tissue but could be distinguished by the fact that char debris and subjacent tissue injury arose with the argon burns.The results suggest that both lasers can be used to remove focal atherosclerotic plaque from arteries without inducing excessive thrombogenicity. Rapid healing is observed with both; however, damage to surrounding tissue is significantly greater with a continuous energy delivery laser as opposed to pulsed energy delivery.Work supported in part by: Heart and Stroke Foundation of Ontario, Grant-in-Aid No. 5-17 相似文献
4.
5.
Robert Guidoin PhD Allan R. Downs MD Xavier Barral MD Michel Marois MD Paul-Emile Roy MD Martin King P. Eng Camille Gosselin MD 《Annals of vascular surgery》1986,1(3):369-373
One of the early diamond crimped knitted polyester (Dacron) grafts was surgically excised after implantation for 25 years in the aorto-billiac position because of false aneurysm formation at the three anastomotic sites. The sutures were no longer visible. While the areas around the false aneurysm were poorly incorporated, the graft limbs were well encapsulated with some endothelial-like cells on the luminal surface. The integrity of the graft was well preserved despite mild fraying and the disruption of one stitch. 相似文献
6.
BackgroundIrrespective of the treatment method, union is the ultimate goal of any fracture treatment. However, nowadays, rather than the physician-based clinico-radiological methods, the patient-reported outcome measurements assessing their quality of life and function are gaining much popularity. This is specifically true in the part of the world where the patient needs almost complete degree of hip/knee flexion – for social, cultural, religious or occupational reason(s). The ability to squat can assess the mobility and stability of joints and thus the quality of squatting is a proxy reflection of the functional outcome after fixation of lower limb fracture. Thus, we studied to determine the inter-observer and intra-observer reliability of Radiographic Union Score for Tibia (RUST) and Squat and Smile (S & S) test in clinical photograph. We further calculated the sensitivity and specificity of S & S test in predicting healing of lower limb fracture fixed by intramedullary interlocking nail considering RUST as the gold standard.MethodsThis was a retrospective study of prospectively collected data of solid Surgical Implant Generation Network (SIGN) intramedullary interlocking nailing from a single, university-based, high volume tertiary center where 56 consecutive adults with either tibial or femoral shaft fractures fixed with a SIGN nail within one year and not requiring any surgery till minimum of eighteen-month follow-up were included. Cases without either Anterior-Posterior (AP) view and/or Lateral (Lat.) view follow-up x-ray(s) or proper S & S clinical photograph (at least 1.5-year post fixation) were excluded. The x-rays (RUST criteria) and clinical photograph (S & S grading) were scored by two independent and blinded observers each and repeated after 1 month.ResultsThe overall intra-observer reliability was from 0.773 to 0.825 and inter-observer reliability from 0.635 to 0.757 for RUST scoring which was from 0.687 to 0.785 and from 0.301 to 0.650 respectively for S & S scoring. The sensitivity and specificity of S & S in predicting fracture healing were up to 82.22% and 63.64% respectively.ConclusionThe S & S test is reliable to predict the healing of lower limb fracture fixed with an intramedullary nail. The test is more useful to determine healed fractures than to determine non-healed ones. (sensitivity being higher than specificity) 相似文献
7.
孙颖 《中国烧伤创疡杂志》2021,(3):211-214
目的 观察湿润烧伤膏治疗剖宫产及会阴侧切术后切口愈合不良的临床疗效.方法 选取2017年6月至2019年12月廊坊市第四人民医院收治的60例剖宫产及会阴侧切术后切口愈合不良产妇作为研究对象,并按照随机数表法将其随机分为观察组与对照组,每组30例,观察组患者局部切口采用湿润烧伤膏换药治疗,对照组患者局部切口采用常规碘伏消... 相似文献
8.
目的 观察健身气功六字诀对中老年人生存质量的影响.方法 采用随机数字表法将受试者随机分为六字诀习练组和对照组,应用WHOQOL-BREF量表中文版作6个月后的评定.结果 6个月后,习练组在生存质量主观感觉( 3.59±0.69)分、健康状况主观感觉(3.22±0.96)分、生理领域(89.19±13.68)分、心理领域(79.74±11.26)分,均高于对照组,差异均有统计学意义(P均<0.01).习练组习练后在生存质量主观感觉、健康状况主观感觉、生理领域、心理领域得分均高于同组前期,差异有统计学意义(P<0.01).结论 六字诀可改善中老年人的生存质量. 相似文献
9.
Habiboallah G Nasroallah S Mahdi Z Nasser MS Massoud Z Ehsan BN Mina ZJ Heidar P 《Journal of ethnopharmacology》2008,120(3):335-341
Ethnopharmacological relevance
The experimental finding of Asian traditional medicine revealed the pharmacological effect of the local application of ghee which was taken from cow butterfat and the rhizomes of Curcuma longa. These materials significantly improved the healing process of the wound. In addition, ancient physicians of Middle East discovered that the powdered rhizomes of Curcuma longa (common turmeric) also had impressive medicinal qualities. Over the centuries, this spice has been used as a pain relieving, anti-inflammatory agent to relieve pain and inflammation in the skin and muscles.Aim of the study
We decided to mix ghee which was taken from sheep butterfat with the powdered rhizomes of Curcuma longa to formulate a novel cost-benefit material and then, evaluate its potential therapeutic effect on acceleration of surgical wound healing; moreover, this present study was performed to compare the effects of Curcuma longa–ghee formulation and hyaluronic acid on gingival wound healing following surgery.Materials and methods
Five healthy 3-year-old male beagle dogs were used in this study. They had intact teeth and the clinical and radiographic examination revealed no periodontal disease. Ghee was obtained from the refined sheep butterfat heated to 70 °C mixed with the powdered rhizomes of Curcuma longa and was applied with two different ratios including materials A and B. Randomly, these three materials including hyaluronic acid, materials A and B were applied topically in test regions and then covered with periodontal pack. Histological changes were monitored in days 4 and 7 after operation to evaluate the inflammatory and repair stage of healing process.Results
We observed significant difference in the inflammatory and repair parameters of the healing process between cases treated with this new formulation and cases of hyaluronic acid application.Conclusion
The results suggested a positive potential therapeutic effect on surgical wound healing particularly improvement of periodontal treatment consequences after surgery. 相似文献10.
Moraes Tde M Rodrigues CM Kushima H Bauab TM Villegas W Pellizzon CH Brito AR Hiruma-Lima CA 《Journal of ethnopharmacology》2008,120(2):161-168