排序方式: 共有27条查询结果,搜索用时 17 毫秒
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Chatchawan Silpakit Suwanee Sirilerttrakul Manmana Jirajarus Thitiya Sirisinha Ekaphop Sirachainan Vorachai Ratanatharathorn 《Quality of life research》2006,15(1):167-172
The objective of this study was to assess the psychometric properties of the Thai version of the European Organization for
Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) version 3.0. The questionnaire was completed
by 310 cancer patients during their follow-up at 2 teaching hospital oncology clinics. About 70% of participants had advanced
stage of cancer and 72% had been receiving chemotherapy. Cronbach’s α coefficients of the six scales were above 0.7, except for cognitive and social function scales. All test–retest reliability
coefficients were high. Multitrait scaling analysis showed that all item-scale correlation coefficients met the standards
of convergent and discriminant validity. Most scales and items could discriminate between subgroups of patients with different
clinical status assessed with the Eastern Cooperative Oncology Group (ECOG) scale. The results suggested that the EORTC QLQ-C30
and the Functional Assessment of Cancer Therapy – General (FACT-G) measured different aspects of quality of life and should
be independently used. Testing psychometric properties of the EORTC QLQ-C30 in heterogeneous diagnostic group yield similar
results as found in homogeneous group. These results support that the EORTC QLQ-C30 (version 3.0) has proven to be a reliable
and valid measure of the quality of life in Thai patients with various types of cancer. 相似文献
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目的评估胃癌、大肠癌患者的生命质量,探讨与之相关的影响因素。方法采用癌症治疗功能评价系统量表体系中的共性模块(FACT-G)调查了52例胃癌患者和50例大肠癌患者。各影响生命质量因素的差异程度经t检验及方差分析处理,对不同年龄、性别、文化程度、病种、病期及经过治疗与否的患者的FACT-G得分进行比较。运用最优尺度回归分析、多重线性回归分析和判别方程了解生命质量各个子量表与病期的关系。结果较早期患者及经过综合治疗后的患者的生命质量较好;年龄、性别对生命质量的影响不大。FACT-G量表对大肠癌的效度可能要比对胃癌更好;以手术为主的综合治疗措施可在一定程度上提高患者的生命质量。结论生命质量应成为评价恶性肿瘤治疗疗效的指标之一;开展胃肠道恶性肿瘤的生命质量测评对临床诊疗工作有一定的指导意义。 相似文献
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目的分析SF-36中文版用于口腔癌患者生活质量(quality of life,QOL)测定的心理测量学特性。方法采用SF-36中文版对97例确诊为口腔鳞癌的连续患者进行QOL的测量,分析量表的信度、效度和反映度。结果量表8个领域的克朗巴赫系数为0.76~0.96,分半信度为0.69;35个条目可提取9个因子,累计方差贡献率为74.2%;以FACT—G第四版中文版为效标,其效标效度为0.734;量表能敏感的区分口腔癌急者QOL随时间的变化,对已知的两组口腔癌患者术前QOL的差异也表现出一定的区分能力。结论SF-36用于国人口腔癌患者生活质量的测定具有较好的信度、效度和反映度,因而具有一定的实用价值。 相似文献
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B Holzner G Kemmler B Sperner-Unterweger M Kopp M Dünser R Margreiter I Marschitz D Nachbaur W.W Fleischhacker R Greil 《European journal of cancer (Oxford, England : 1990)》2001,37(18):270
Two widely used quality of life questionnaires European Organization for Research and Treatment of Cancer Core (EORTC QLQ-C30), Functional Assessment of Cancer Therapy—General (FACT-G) were examined for their comparability using four different groups of cancer patients. During a follow-up investigation, 418 cancer patients (Hodgkin's disease, breast cancer, bone marrow transplantation (BMT), chronic lymphatic leukaemia (CLL) completed both the EORTC QLC-C30 and the FACT-G during the same session. For an illustration of the differences between the two Quality of Life (QoL) instruments, pairs of diagnostic groups were formed and their QoL scores using the EORTC QLQ-C30 and FACT-G compared. The corresponding subscales of the EORTC-QLC-C30 and the FACT-G show only low to moderate intercorrelations across all four groups of cancer patients studied. In particular, a comparison of pairs, namely Hodgkin's disease versus breast cancer patients and BMT versus CLL patients, highlights substantial differences in the corresponding subscales of the EORTC QLQ-C30 and the FACT-G. The results of the QoL investigations should not be interpreted independently of the instrument used and an interpretation of results must be based on the contents of items of the respective questionnaires. 相似文献
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Bacik J. Mazumdar M. Murphy B.A. Fairclough D.L. Eremenco S. Mariani T. Motzer R.J. Cella D. 《Quality of life research》2004,13(1):137-154
PURPOSE: This paper reports on the development and validation of two biologic response modifier (BRM) subscales for use with the Functional Assessment of Cancer Therapy-General (FACT-G) quality of life (QOL) questionnaire. METHODS: Using the FACT-G as a base, 17 additional questions related to symptoms common to interferon and retinoid therapy were developed. Data collected at baseline (n = 191) and week 2 (n = 168) in a randomized trial of interferon +/- 13-cis-retinoic acid in advanced renal cell carcinoma patients were used to validate this measure. RESULTS: Using a combined empirical and conceptual approach, the 17 questions were reduced to 13 questions consisting of two subscales: 'BRM-physical' (7 items; baseline coefficient alpha(alpha) = 0.70; week-2 alpha = 0.75) and 'BRM-mental' (6 items; baseline alpha = 0.79; week-2 alpha = 0.78). Internal consistency of the trial outcome index (TOI) combining physical well-being, functional well-being and the BRM subscales, was 0.91 for baseline assessments and 0.92 for week 2. Discriminant validity was demonstrated for the TOI by its ability to differentiate among prognostic risk groups, and for the total FACT-G, TOI and total FACT-BRM scores by their ability to distinguish between groups differing in performance, response and toxicity status. CONCLUSIONS: The 'BRM-physical' and 'BRM-mental' subscales can be combined with the FACT-G to form the 'FACT BRM' scale, useful for measuring QOL in cancer patients who are receiving treatment with biologic response modifiers. 相似文献
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A prospective comparison of quality of life measures for patients with esophageal cancer 总被引:3,自引:0,他引:3
Jane?M.?BlazebyEmail author Vasia?Kavadas Craig?W.?Vickery Rosemary?Greenwood Richard?G.?Berrisford Derek?Alderson 《Quality of life research》2005,14(2):387-393
Among the most widely used instruments to assess quality of life (QOL) in patients with cancer are the European Organization for Research and Treatment of Cancer core questionnaire (EORTC QLQ-C30) and the Functional Assessment of Chronic Illness Therapy, cancer instrument (FACT-G). This study compared these approaches in patients who had undergone esophagectomy for cancer. The EORTC core questionnaire and esophageal module and the FACT-G and esophageal scale were completed by 57 patients. Missing data, relationships between QOL scales and analyses of patients preferences were examined. There were 14/2736 (0.5%) missing items from EORTC questionnaires and 45/2565 (1.8%) from FACT instruments (p < 0.01). Relationships between corresponding generic EORTC and FACT scales were average to good (r 0.57) except for the social function scale (r = 0.01). EORTC symptom scores were moderately correlated with the FACT general scale, but poorly related to the FACT esophageal scale (r < 0.28). EORTC swallowing scores were moderately correlated with all FACT scales. The FACT-E and EORTC QLQ-C30 measure assess similar generic aspects of QOL (except social function). EORTC esophageal symptom scores relate poorly to FACT esophageal scales, except for swallowing. Choice of QOL measure after esophagectomy for cancer depends upon outcomes of interest. Future studies will determine which instruments are appropriate in each context. 相似文献
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Guru Karthikeyan Divita Jumnani Rama Prabhu Udaya Kumar Manoor Sanjay Sudhakar Supe 《Indian Journal of Palliative Care》2012,18(3):165-175