土耳其斯坦东毕吸虫磷酸丙糖异构酶基因的克隆及其序列分析

目的 克隆土耳其斯坦东毕吸虫磷酸丙糖异构酶的全长基因。方法 根据日本血吸虫和曼氏血吸虫磷酸丙糖异构酶基因的保守区设计引物，利用RT—PCR扩增出土耳其斯坦东毕吸虫磷酸丙糖异构酶基闪的大片段，再结合RACE技术分别得到磷酸丙糖异构酶基因的3’端和5’端，将3部分序列拼接后获得磷酸丙糖异构酶基因全长cDNA序列，并提交GenBank。结果 成功克隆了土耳其斯坦东毕吸虫磷酸丙糖异构酶基因全长cDNA序列并提交GenBank，登录号为DQ092331。结论 土耳其斯坦东毕吸虫磷酸丙糖异构酶基因全长cDNA的克隆为进一步表达及其生物学性能的分析提供了理论基础。     

丙型肝炎病毒在土耳其人群中传播的危险因素

丙型肝炎病毒(H CV)传播的危险因素随国家和地区的变化而有所不同。该文旨在探讨土耳其人群中与H CV传播有关的危险因素。研究选取1996—2002年间伊斯坦布尔大学医学院胃肠肝病科收治的H CV感染者320例,患者于住院或出院后门诊随访期间被发现血清H CV抗体阳性。对所有患者询问其感染H CV的危险因素,如输血史、手术史、住院治疗、血液透析、静脉药物注射、可疑的性接触、文身、针灸、牙科操作、修甲修脚、滴血盟誓史、割礼或包皮环切、流产、围产期危险因素等。该研究中,男性和女性患者数量及百分比分别为139例(43.4%)与181例(56.6%),…     

土耳其传统药简介

土耳其是世界上使用传统药较多的国家之一。过去我国对其介绍甚少。现根据近来资料简要介绍下面327种有生理活性的传统药,以供参考。     

百字健康

河南个别地方滥用药物频现多胞胎；巨浪中大象“救”孩子；树根头竟冒充野山参；中国百岁老人如皋最多；死在棺材里分娩；一家三姐妹全是“两性人”；土耳其一工人泪腺以能喷射牛奶。     

禽流感病毒突变加大了对人类的威胁

《自然》杂志（Nature，2006，439：248-249）1月19日报道，禽流感病毒的突变警钟已经拉响，禽流感加大了对人类的威胁。报道说，土耳其短时间内禽流感爆发给世人敲响了警钟，世界卫生组织位于伦敦的合作中心——国家医学研究院（NIMR）的科学家们已经确定了在禽流感病毒的序列中发生了3个突变，其中至少有2个使病毒更加适应人类。这些科学家们迫切地想知道这些病毒在土耳其的传播与先前在亚洲出现的禽流感病毒的传播有什么不同，他们特别关注人类之间禽流感传播的可能性。     

伊斯坦布尔的石头汤

置身繁华热闹的伊斯坦布尔,别具特色的中东风情扑面而来。土耳其烤肉串诱人食欲,奶酪炖蔬菜蘑菇软嫩鲜香,香煎比目鱼、鲜烤鲈鱼更是鲜美可口。美食当前,我最感兴趣的是当地有名的石头汤。伊斯坦布尔街头,卖石头汤的虽然大多是路边摊,却很干净整齐。长条餐桌上,铺着具有民族风情的桌布。一排石头汤像整装待发的士兵,静静地列队等待人们品尝。     

Low eradication rate of Helicobacter pylori with triple 7-14 days and quadriple therapy in Turkey

AIM:The eradication rate of Helicobacter pylori (H pylon) shows variation among countries and regimens of treatment.We aimed to study the eradication rates of different regimens in our region and some factors affecting the rate of eradication.METHODS:One hundred and sixty-four Hpylori positivepatients (68 males, 96 females; mean age:48±12 years)with duodenal or gastric ulcer without a smoking history were included in the study. The patients were divided into three groups according to the treatment regimens. Omeprazole 20mg, clarithromycin 500mg, amoxicillin 1g were given twice daily for 1 week (Group I) and 2 weeks (Group Ⅱ).Patients in Group Ⅲ received bismuth subsitrate 300mg,tetracyline 500 mg and metronidazole 500mg four times daily in addition to Omeprazole 20mg twice daily.Two biopsies each before and after treatment were obtained from antrum and corpus, and histopathologically evaluated.Eradication was assumed to be successful if no Hpylorus was detected from four biopsy specimens taken after treatment. The effects of factors like age, sex, Hpyloridensity on antrum and corpus before treatment, the total Hpylori density, and the inflammation scores on the rate of Hpylori eradication were evaluated.RESULTS:The overall eradication rate was 42%. The rates in groups Ⅱ and Ⅲ were statistically higher than that in group I (P<0.05). The rates of eradication were 24.5%,40.7% and 61.5% in groups Ⅰ, Ⅱ and Ⅲ, respectively. The eradication rate was negatively related to either corpus Hpylori density or total Hpyloridensity (P<0.05).The median age was older in the group in which the eradication failed in comparison to that with successful eradication (55yr vs 39yr, P<0.001). No correlation between sex and Hpylori eradication was found.CONCLUSION: Our rates of eradication were significantly lower when compared to those reported in literature.We believe that advanced age and high Hpyloridensity are negative predictive factors for the rate of Hpylorieradication.     

世界特色医院

当今世界,人们到处都可以看到各种综合性医院和专科医院,同时也出现了某些新型的特色医院。 鱼塘医院在土耳其的康加尔,有一个含有硫磺的温水鱼塘,塘内有许多棕绿色的状如带鱼的鱼。这种鱼嗜痂成癖,专爱吃人体上的癣斑和伤口腐肉。患者只要安坐在鱼塘中,这些鱼“医生”便会不请自来。用不了一个星期,病人就会觉得一身轻松——身上的皮肤病或者伤口霍然而愈。     

Assessment on self-care,mobility and social function of children with spina bifida in Turkey

The aim of the study was to investigate the functional performance in children with spina bifida, using the Pediatric Evaluation of Disability Inventory(PEDI) to look into capacity of twenty-eight children with spina bifida with lesions at different levels in different dimensions of selfcare, mobility and social function. Mean age of the patients was 3.5 ± 2.3(1–10) years. In the muscle test carried out, 13 patients(44.8%) had no movements including pelvic elevation in lower extremity muscles and they were at level 5. Sixteen patients(54%) were non-ambulatory according to the Hoofer ambulation classification. Raw and scale scores in the self-care, mobility and social function domains both in the functional skill scale and in the caregiver scale were found to be lower compared to the data of the normal population. A statistically significant correlation was observed in the self-care values of the Functional Skills Scales and the Caregiver Assistance Scale measurements, which was positive for age and negative for Functional Ambulation Scale and muscle test(P 0.05). A positive relation was found between the Functional Skills Scales-mobility area and age while a negative relation was observed between Functional Ambulation Scale and muscle test(P 0.005). A negative relation was also found between Caregiver Assistance Scale-mobility and Functional Ambulation Scale and muscle test(P 0.005). In our study, the functional performance of the children was found to be low. Low-level lesions, encouraging muscular strength and independence in mobility are all very important factors for functional independence.     

土耳其斯坦东毕吸虫结节亚种染色体的G带研究

土耳其斯坦东毕吸虫结节亚种染色体的Ｇ带核型表明：Ｎｏ．Ｉ染色体，短臂２条强带，末端为１条中强带，长臂７－８条强带，末端２条强带较宽；Ｎｏ．ⅡＺ染色体，短臂２条强带，末端的中强带较宽，长臂有４条等蹭隔的强带，Ｗ染色体，短臂为１条强带，未端为１条阴性带，长臂５条强带；Ｎｏ．Ⅲ染色体，短臂２条强带，长臂５－６条强带；Ｎｏ．Ⅳ染色体长臂５－６条强带；Ｎｏ．Ｖ染色体，长臂有４条强带；Ｎｏ．ＶＩ染色体，短臂有