全文获取类型
收费全文 | 16579篇 |
免费 | 790篇 |
国内免费 | 257篇 |
专业分类
耳鼻咽喉 | 505篇 |
儿科学 | 720篇 |
妇产科学 | 184篇 |
基础医学 | 1802篇 |
口腔科学 | 551篇 |
临床医学 | 1040篇 |
内科学 | 2660篇 |
皮肤病学 | 723篇 |
神经病学 | 1446篇 |
特种医学 | 1471篇 |
外科学 | 3135篇 |
综合类 | 988篇 |
现状与发展 | 1篇 |
预防医学 | 547篇 |
眼科学 | 448篇 |
药学 | 668篇 |
2篇 | |
中国医学 | 267篇 |
肿瘤学 | 468篇 |
出版年
2024年 | 24篇 |
2023年 | 148篇 |
2022年 | 362篇 |
2021年 | 495篇 |
2020年 | 269篇 |
2019年 | 447篇 |
2018年 | 531篇 |
2017年 | 424篇 |
2016年 | 266篇 |
2015年 | 255篇 |
2014年 | 402篇 |
2013年 | 569篇 |
2012年 | 293篇 |
2011年 | 328篇 |
2010年 | 318篇 |
2009年 | 327篇 |
2008年 | 460篇 |
2007年 | 454篇 |
2006年 | 324篇 |
2005年 | 249篇 |
2004年 | 275篇 |
2003年 | 431篇 |
2002年 | 1273篇 |
2001年 | 1595篇 |
2000年 | 1796篇 |
1999年 | 1150篇 |
1998年 | 1132篇 |
1997年 | 1022篇 |
1996年 | 583篇 |
1995年 | 270篇 |
1994年 | 128篇 |
1993年 | 99篇 |
1992年 | 88篇 |
1991年 | 78篇 |
1990年 | 76篇 |
1989年 | 83篇 |
1988年 | 56篇 |
1987年 | 47篇 |
1986年 | 34篇 |
1985年 | 65篇 |
1984年 | 75篇 |
1983年 | 52篇 |
1982年 | 52篇 |
1981年 | 41篇 |
1980年 | 43篇 |
1979年 | 26篇 |
1978年 | 20篇 |
1977年 | 32篇 |
1976年 | 18篇 |
1973年 | 12篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
Kensuke Kudou Hiroshi Saeki Yuichiro Nakashima Shun Sasaki Tomoko Jogo Kosuke Hirose Qingjiang Hu Yasuo Tsuda Koichi Kimura Ryota Nakanishi Nobuhide Kubo Koji Ando Eiji Oki Tetsuo Ikeda Yoshihiko Maehara 《American journal of surgery》2019,217(4):757-763
Background
There were few studies assessed the postoperative sarcopenia in patients with cancers. The objective of present study was to assess whether postoperative development of sarcopenia could predict a poor prognosis in patients with adenocarcinoma of esophagogastric junction, (AEG) and upper gastric cancer (UGC).Methods
Patients with AEG and UGC who were judged as non-sarcopenic before surgery were reassessed the presence of postoperative development of sarcopenia 6 months after surgery. Patients were divided into the development group or non-development group, and clinicopathological factors and prognosis between these two groups were analyzed.Results
The 5-year overall survival rates were significantly poorer in the development group than non-development group (68.0% vs. 92.6%, P?=?0.0118). Multivariate analyses showed that postoperative development of sarcopenia was an independent prognostic factor for poor overall survival (P?=?0.0237).Conclusions
Postoperative development of sarcopenia was associated with a poor prognosis in patients with AEG and UGC. 相似文献6.
《Drug discovery today》2022,27(6):1733-1742
Compounds that exhibit assay interference or undesirable mechanisms of bioactivity are routinely encountered in assays at various stages of drug discovery. We observed that assays for the investigation of thiol-reactive and redox-active compounds have not been collected in a comprehensive review. Here, we review these assays and subject them to experimental optimization to improve their reliability. We demonstrate the usefulness of our assay cascade by assaying a library of bioactive compounds, chemical probes, and a set of approved drugs. These high-throughput assays should complement the array of wet-lab and in silico assays during the initial stages of hit discovery campaigns to pursue only hit compounds with tractable mechanisms of action. 相似文献
7.
8.
9.
BackgroundWomen suffering from kidney disease are more prone to fertility problems, due to uremia. Fortunately, their fertility rate increases dramatically after renal transplantation. This study analyzes the predictors/risk factors of successful pregnancy with live birth outcome while presenting an overview of the 7-year experience of a single center.MethodsThis retrospective cohort study includes 239 women of reproductive age (18–40 years) who underwent renal transplantation in a tertiary Turkish clinic between October 1, 2011, and August 24, 2017. The subjects were invited to take part in a survey questioning their obstetric characteristics and they were assessed in 2 groups: fertile and infertile. Multivariable linear regression analysis was conducted to determine the predictors of a successful pregnancy.ResultsThirty-five 35 patients wished to become pregnant: 12 got pregnant spontaneously, while 21 failed to become pregnant (spontaneously). The mean age of the patients at the survey was 34 ± 7. Regular menstrual cycles after renal transplantation, tacrolimus-mycophenolate mofetil maintenance protocol, and age at transplantation were found to be predictors of spontaneous pregnancy. The duration of peritoneal dialysis was significantly longer in the infertile group (48 vs 12 months).ConclusionEnd-stage renal disease's negative impacts, including menstrual abnormality and fertility problems, can be overcome by successful kidney transplantation with appropriate immunosuppression. Minimizing the duration of peritoneal dialysis, particularly in patients who desire future fertility, may be accepted as a logical management strategy. 相似文献
10.
Oliver Sartor MD Daniel Heinrich MD Neil Mariados MD Maria José Méndez Vidal MD Daniel Keizman MD Camilla Thellenberg Karlsson MD Avivit Peer MD Giuseppe Procopio MD Stephen J. Frank MD Kalevi Pulkkanen MD Eli Rosenbaum MD Stefano Severi MD José Trigo MD Lucia Trandafir MD Volker Wagner MD Rui Li MS Luke T. Nordquist MD 《The Prostate》2019,79(14):1683-1691