大黄消炎痛含漱液对固定矫治患者牙周组织影响的研究

目的观察大黄消炎痛含漱液对固定矫治的患者牙周组织的影响。方法将60例需做正畸治疗的患者分为2组,A组和B组患者戴入矫治器前1周、戴入后2周、4周、8周下颌前磨牙菌斑指数、牙龈出血指数、牙周探诊深度。结果固定矫治器的放置会使牙周临床指标显著增高,牙龈出现轻、中度炎症,应用大黄消炎痛含漱液漱口能使牙周临床指标明显降低。结论固定矫治器的放置可影响牙周组织的健康,对接受固定矫治的患者应用抗菌、消炎药物漱口是非常重要的。     

持续腹腔冲洗治疗胰十二指肠切除术后胰瘘致腹腔出血的观察及护理

目的 介绍应用去甲肾上腺素进行持续腹腔冲洗引流治疗胰十二指肠切除术后胰瘘致腹腔出血患者的护理方法.方法 对12例胰十二指肠切除术后胰瘘致腹腔出血的患者,应用去甲肾上腺素进行腹腔冲洗引流的治疗及护理.结果 本组12例患者通过去甲肾上腺素持续腹腔冲洗引流的治疗及护理,出血症状逐渐好转并治愈.结论 应用去甲肾上腺素持续腹腔冲洗是一种简单、有效的治疗方法,做好引流管冲洗的护理是治疗胰十二指肠切除术后并发腹腔出血的有效方法.     

止嗽散加减治疗外感咳嗽的疗效观察

目的观察止嗽散加减治疗外感咳嗽的疗效。方法2011年1月至2011年12月符合诊断标准的门诊病例100例，随机分为两组。治疗组采用止嗽散加减治疗，对照组口服枇杷止咳糖浆。结果治疗组总有效率96％，对照组总有效率80％，经统计学处理，两组差异有高度统计意义（P〈O．05）。结论止嗽散加减治疗外感咳嗽疗效显著。     

Graft rinse prior to reperfusion in liver transplantation: literature review and online survey within the Eurotransplant community

Graft rinse prior reperfusion in liver transplantation (LT) is believed to reduce the incidence of postreperfusion syndrome and improve clinical outcome. A MEDLINE search was performed to obtain a comprehensive review of the published literature dealing with graft rinse in LT. Moreover, all thirty‐four LT centers in the Eurotransplant (ET) region were invited to participate in an online survey to whether or not graft rinse is performed and whether further research in the field is needed. Seventeen reports have been found to investigate graft rinse protocols in 1894 LT recipients. Eighteen of the thirty centers that participated in the online survey performed graft rinse prior reperfusion in LT. The most commonly used rinse solution was albumin. Nineteen centers stated interest in participating in a multicenter RCT in the field. The published literature does not provide concluding appraisal of the benefit of graft rinse in LT. Graft rinse protocols are not standardized and are based on personal experience. Appropriately designed clinical trials addressing the topic are demanded. The online survey appears to be a helpful tool for the evaluation of clinical practice and future research topics in the transplant community.     

A non-invasive oral rinse assay predicts bone marrow engraftment and 6 months prognosis following allogeneic hematopoietic stem cell transplantation

J Oral Pathol Med (2012) 41 : 165–170 Background: We have previously shown in a pediatric Hematopoietic stem cell transplant (HSCT) population that a non‐invasive oral rinse can be used to monitor engraftment, neutrophil tissue delivery and susceptibility to infection post‐HSCT. Methods: Using the same oral rinse protocol, we studied neutrophil tissue delivery kinetics and its relationship to clinical parameters and outcomes following HSCT in 29 adult patients. Oral neutrophil counts were compared to circulating neutrophil levels, oral mucositis scores and patient health status at 6 months post‐HSCT. Results: Neutrophils were detected on average 8.4 ± 3.4 SD days earlier in the oral tissues than in the blood circulation, enabling us to confirm successful engraftment more than one week earlier than when using blood neutrophil counts alone. As well, in this population the time‐span between oral engraftment (OE) and blood engraftment (BE) was a consistent predictor of treatment outcome at 6 months following HSCT where a BE–OE of <6 days resulted in 100% of patients having a negative outcome. Conclusion: We conclude that monitoring the timing of neutrophil delivery to the oral tissues with a non‐invasive oral rinse has the potential to allow the physician to identify those patients who are at a high risk of HSCT failure within just a few weeks of the initiation of treatment.     

Exudative hemorrhagic retinopathy related to all-trans retinoic acid differentiation syndrome in a patient with acute promyelocytic leukemia

Dear Editor,We report a case of significant exudative hemorrhagic retinopathy attributed to differentiation syndrome(DS).DS is a systemic inflammatory condition seen in patients with acute promyelocytic leukemia(APML)undergoing treatment with all-trans retinoic acid(ATRA).DS can lead to endothelial injury and capillary leakage throughout the body.Treatment with corticosteroids during chemotherapy has been shown to reduce the risk of developing DS[1-2].There are limited reports of the ocular manifestations of DS in the literature,including pale yellow choroidal lesions,scattered retinal hemorrhages,and serous retinal detachments[3-5].