A bibliometric analysis of the 100 most influential papers in burns

The importance of a published paper to a particular area is reflected in the quantity of citations obtained from peers. In burns, it is unknown which papers have been the most influential on this specialty. The purpose of our study was to identify the 100 most cited papers in burns and to analyze their characteristics. Twenty-seven journals were chosen for analysis. These included high impact factor scientific journals and journals dedicated to burns and trauma. Only twelve of these journals contributed to the 100 most cited papers in burns and we analyzed each paper individually looking at its subject matter, authorship, article type, institution, country and year of publication. Our citation analysis revealed an interesting mix of clinical and scientific papers that documents the key landmarks in burn care over the past 66 years.     

Clinician accuracy when subjectively interpreting articulating paper markings

Aims:

The aim of this study was to determine whether Subjective Interpretation of paper markings is a reliable method for identifying the relative occlusal force content of tooth contacts.

Methodology:

295 clinicians selected the “Most Forceful” and “Least Forceful” occlusal contacts in six occlusal-view photographs of articulating paper marks that were later compared against computerized occlusal analysis relative occlusal force measurements of the same tooth contacts. Means and standard deviations were calculated by years in clinical practice and by number of occlusion courses taken. A Chi-square analysis was also performed.

Results:

The mean correct for 295 participant dentists was 1·53 (±1·234). There were no significant differences found for years in practice (P>0·16) or number of occlusion courses taken (P>0·75). The Chi-square analysis showed a sensitivity of 12·6%, a specificity of 12·4%, a positive predictive value of 12·58%, and a negative predictive value of 12·42%. Chance was calculated at 12·5% correct.

Conclusions:

Subjective Interpretation is an ineffective clinical method for determining the relative occlusal force content of tooth contacts. The reported low scores obtained from a large group of participant dentists suggest clinicians are unable to reliably differentiate high and low occlusal force from looking at articulating paper marks. This longstanding method of visually observing articulating paper marks for occlusal contact force content should be replaced with a measurement-based, objective method.     

4例高龄肠系膜上动脉栓塞患者肠大部分切除的术后护理

目的探讨高龄肠系膜上动脉栓塞致肠大部切除患者的术后护理方法。方法在常规护理的基础上，综合应用快速康复理念的方法和原则对患者进行综合护理，并结合近期相关文献进行经验总结。结果经过精心护理4例患者均痊愈出院。治疗期间无护理差错及护患纠纷发生，患者满意度达到100％。结论科学有效的护理措施是保证高龄肠系膜上动脉栓塞致肠大部切除患者术后康复的关键。     

哈尔滨市高校教师职业倦怠现况分析

目的了解哈尔滨市高校教师职业倦怠现况,发现高校职业倦怠高发人群,为相关部门制订考核目标和预防救助教师职业倦怠措施提供基础数据。方法采用职业倦怠调查问卷（MBI问卷）调查哈尔滨市3所高校180名教师和教育工作者,影响因素涵盖性别、年龄、学历、专业技术职务、工作年限、是否承担行政工作、薪资收入等。结果高校教师在情绪枯竭、去人格化倾向方面与参考值存在偏差,个人成就感方面自我评价偏低,对于工作的完美感和认同度上存在缺失。每次出现职业倦怠状况表现的3个维度侧重点各有不同;年龄在36～45岁之间具有副高级专业技术职称的人群是职业倦怠的高发人群。职业倦怠在工作过程中反复出现呈周期性变化。结论哈尔滨市高校教师个人成就感低,自我高预期值与现实工作中所取得的实际工作绩效间存在一定的落差;应根据调查分析的结果,制定考核和预防救助办法。     

On the Origin of the Transthyretin Val30Met Familial Amyloid Polyneuropathy

Transthyretin (TTR) familial amyloid polyneuropathy is a severe autosomal dominant neuropathy of adulthood, frequently linked to the pathogenic Val30Met variant of the TTR gene. The condition was initially described in northern Portugal, which is the first focus of the disease. Other important clusters of families are found in Sweden, Japan and South America.
The origin of the Val30Met mutation and its distribution through the populations remains unclear. In the present work, we aimed at refining the history of the Val30Met mutation in patients affected with TTR amyloid neuropathy from Portugal, Sweden and Brazil. The decay of haplotype sharing was studied in 60 patients to estimate the age of the Most Recent Common Ancestor (MRCA) of mutation carriers in these populations. Our results showed a common haplotype in Portuguese and Brazilian patients and an age estimate of the MRCA of 750 and 650 years, respectively. In contrast, a different haplotype was found in the Swedish Val30Met patients with a corresponding age estimate for the MRCA, of 375 years.
This work strengthens the hypothesis of different founders in Portuguese and Swedish Val30Met carriers and suggested a Portuguese origin of the Brazilian mutation. The age estimates of the MRCA are in line with the current historical knowledge of these populations.     

高危新生儿家属心理需求的调查分析

对 18 5例高危新生儿家属进行问卷调查 ,结果显示 :高危新生儿家属的心理需求中 ,想知道病儿目前的治疗、与医生商量病情等方面具有强烈的愿望。通过调查 ,找出存在于这些患儿家属中的共性问题 ,以寻求有效措施帮助患儿家属减轻心理负担 ,使患儿获得更有效的社会支持 ,也为临床护理工作提供方向     

两套视觉电生理检查系统的比较

目的:对比国特GT-2000NV与RETIscan两套视觉电生理检查系统对正常青年人检查的结果。方法:20例正常军校学员用国特和RETIscan两套系统进行图形视觉诱发电位(PVEP)、视网膜电图(ERG)、多焦视网膜电图(mERG)的检测,两套系统的各相应参数调整至相同或相近。结果:两套系统所检测各结果中除Max-ERGa波幅值外,PVEP和常规ERG的其余各值及mERG在两套系统中差异均有显著性意义。PVEPP100峰时、Rod-ERGa波幅值、Rod-ERGb波峰时、Cone-ERGb波峰时在两套系统的测量中,在α=0.05水准上无相关性,而PVEPP100幅值和常规ERG其余结果在两套系统中均表现为正相关,其中Rod-ERGb波幅值、Max-ERGb波幅值、峰时、Cone-ERGb波幅值、Flick-ERGP2波幅值的相关系数分别为0.679,0.832,0.702,0.756,0.766。mERG环形p波功率密度及各象限p波功率密度及峰时在两套系统中均为正相关,环形p波峰时在α=0.05水准上第1,2,3环无相关性,而第4、5环在α=0.05水准上为正相关。其中环形第1,2,3,4,5环功率密度的相关系数分别为0.443,0.627,0.591,0.592,0.739,其峰时的相关系数分别为0.292,0.269,0.302,0.432,0.810。两套系统在mERG测量中,p波功率密度及峰时的变化具有相同的趋势。结论:国特和RETIscan两套系统在视觉电生理的测量中,其各结果的正常值     

Immunohistochemical collagen analysis of the most superficial layer in adult articular cartilage

We investigated immunohistochemically the collagen type of the most superficial layer in 10 normal adult human articular cartilage specimens obtained from eight femoral heads and one each of the femoral condyle and the talus using routine light microscopy and polarizing microscopy. A membrane-like structure with strong bire-fringence covering the articular surface was observed under polarizing microscopy in each specimen. This structure was stained with anti-type I and anti-type III collagen antibodies but not with anti-type II collagen antibody. This immunohistochemical finding was identical to that in synovial tissue. The results of this study confirm that the most superficial layer of adult normal articular cartilage consists not of type II collagen but of types I and III, and that this layer is absolutely independent from its deeper layer.     

组织工程化软骨修复软骨损伤

背景:目前临床上多采用自体或异体软骨移植、软骨膜或骨膜移植、软骨细胞移植等方法进行软骨损伤修复,但均因取材局限、免疫排斥等导致效果不佳。利用组织工程的方法再造软骨,为软骨缺损的临床修复提供了新的思路与途径。目的:利用SCI数据库文献检索和深度分析功能,对于组织工程软骨的文献资料趋势进行多层次探讨分析,根据检索文献结果分析组织工程软骨的发展趋势。方法:通过计算机检索SCI数据库中2001/2010有关组织工程软骨的文献,检索词为"软骨(cartilage);组织工程(tissueengineering);软骨细胞(chondrocyte/cartilage cell);软骨组织(cartilage tissue);支架材料(scaffold materials);种子细胞(seed cell)",以文字和图表的形式进行统计和结果分析,描述其分布特征。结果与结论:SCI数据库2001-01/2010-12收录组织工程软骨相关文献总计3137篇,中国在该领域的文献产出量逐渐增多,总体呈上升趋势,Biomaterials《生物材料》杂志发表文献量最多。美国在该领域文献产出量多于其他国家,对该领域研究起到重要作用,发表文献较多的机构集中在美国的哈佛大学,莱斯大学,麻省理工学院,哥伦比亚大学,加利福尼亚大学圣地亚哥分校等。     

Helena,the hidden beauty: Resolving the most common West Eurasian mtDNA control region haplotype by massively parallel sequencing an Italian population sample

The analysis of mitochondrial (mt)DNA is a powerful tool in forensic genetics when nuclear markers fail to give results or maternal relatedness is investigated. The mtDNA control region (CR) contains highly condensed variation and is therefore routinely typed. Some samples exhibit an identical haplotype in this restricted range. Thus, they convey only weak evidence in forensic queries and limited phylogenetic information. However, a CR match does not imply that also the mtDNA coding regions are identical or samples belong to the same phylogenetic lineage. This is especially the case for the most frequent West Eurasian CR haplotype 263G 315.1C 16519C, which is observed in various clades within haplogroup H and occurs at a frequency of 3–4% in many European populations.In this study, we investigated the power of massively parallel complete mtGenome sequencing in 29 Italian samples displaying the most common West Eurasian CR haplotype – and found an unexpected high diversity. Twenty-eight different haplotypes falling into 19 described sub-clades of haplogroup H were revealed in the samples with identical CR sequences. This study demonstrates the benefit of complete mtGenome sequencing for forensic applications to enforce maximum discrimination, more comprehensive heteroplasmy detection, as well as highest phylogenetic resolution.