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1.
目的 调查黑龙江省逊克县火山熔岩地区啮齿动物携带病原体状况.方法 2014年4-9月,采集啮齿动物样本107只,解剖取脏器肺、肾、肝、肾和膀胱样本,采用PCR方法分别扩增10种鼠传病原体的特异性核酸片段,通过基因测序进一步鉴定.结果 在107份鼠肺中共检出汉城型汉坦病毒RNA核酸阳性样本5份,感染率为4.67%;107份鼠肾中共检出钩端螺旋体DNA核酸阳性样本6份,感染率为5.61%;107份鼠脾中共检出巴尔通体DNA核酸阳性样本7份,感染率为6.54%,嗜吞噬细胞无形体4份,感染率为3.74%;107份鼠肝、鼠脾中鼠疫菌、巴贝西原虫、斑点热群立克次体、恙虫病立克次体、莫氏立克次体的DNA核酸检测结果均为阴性;107份鼠膀胱中伯氏疏螺旋体的DNA核酸检测结果为阴性;在鼠体内还存在复合感染情况,感染率为2.80%.结论 黑龙江省逊克县火山熔岩地区啮齿动物中存在汉坦病毒、钩端螺旋体、巴尔通体和嗜吞噬细胞无形体的感染.  相似文献   
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A 51-year-old man was brought to the emergency department after he had drunk 200 mL of fluid from a decorative sparkle lamp. His calcium level was 4.99 mmol/L with a blood gas pH of 7.21. His calcium levels were corrected and his acidosis improved, but his stay in the intensive care department was complicated on day 10 by upper gastrointestinal hemorrhage because of caustic erosions in his stomach. Ten days after admission, he had an emergency right hemicolectomy during which residual luminescent particles were found to have eroded through his cecal mucosa. He eventually died 15 days after admission because of disseminated intravascular coagulopathy and refractory septic shock. This case demonstrates the potential for fatal toxicity associated with ingestion of a common household item.  相似文献   
4.
Computer-aided design (CAD) and computer-aided manufacturing (CAM) have become an increasingly popular part of dentistry over the past 25 years. The technology, which is used in both the dental laboratory and the dental office, can be applied to inlays, onlays, veneers, crowns, fixed partial dentures, implant abutments, and even full-mouth reconstruction. This article discusses the history of CAD/CAM in dentistry and gives an overview of how it works. It also provides information on the advantages and disadvantages, describes the main products available, discusses how to incorporate the new technology into your practice, and addresses future applications.  相似文献   
5.
目的 比较不同全瓷材料对根管治疗后不同程度变色前牙的修复效果.方法 选择根管治疗后前牙变色患者83例(102颗牙),将患牙按牙体变色的程度不同分为轻度变色牙46颗、中度变色牙33颗、重度变色牙23颗.用IPSe-max铸瓷制作全瓷冠修复轻度变色牙18颗、中度变色牙9颗、重度变色牙3颗;用Vita In-ceram渗透氧化铝陶瓷制作全瓷冠修复轻度变色牙14颗、中度变色牙11颗、重度变色牙7颗;用Lava氧化锆陶瓷制作全瓷冠修复轻度变色牙14颗、中度变色牙13颗、重度变色牙13颗.通过Crystaleye比色仪分别对修复体和天然邻牙进行测色,计算总色差△E值,并对全瓷冠与天然邻牙的颜色匹配度进行牙冠颜色评分(CCS).结果 IPS e-max铸瓷修复的轻度变色牙、中度变色牙及重度变色牙,其△E值依次升高(P<0.05),而另外2种材料的△E值在不同程度变色牙组中比较,差异均无统计学意义(P>0.05).在轻、中度变色牙组中,3种材料CCS比较,差异均无统计学意义(P>0.05);在重度变色牙组中,Vita In-ceram、Lava氧化锆材料的CCS优于IPS e-max铸瓷(P<0.05).结论 IPS e-max铸瓷对中、重度变色牙的修复效果较差,而Vita In-ceram渗透氧化铝陶瓷和Lava氧化锆陶瓷对于轻、中、重度变色前牙均有较好的修复效果.  相似文献   
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PURPOSE

All-ceramic crowns are subject to fracture during function. To minimize this common clinical complication, zirconium oxide has been used as the framework for all-ceramic crowns. The aim of this study was to compare the fracture strengths of two computer-aided design/computer-aided manufacturing (CAD/CAM) zirconia crown systems: Lava and Digident.

MATERIALS AND METHODS

Twenty Lava CAD/CAM zirconia crowns and twenty Digident CAD/CAM zirconia crowns were fabricated. A metal die was also duplicated from the original prepared tooth for fracture testing. A universal testing machine was used to determine the fracture strength of the crowns.

RESULTS

The mean fracture strengths were as follows: 54.9 ± 15.6 N for the Lava CAD/CAM zirconia crowns and 87.0 ± 16.0 N for the Digident CAD/CAM zirconia crowns. The difference between the mean fracture strengths of the Lava and Digident crowns was statistically significant (P<.001). Lava CAD/CAM zirconia crowns showed a complete fracture of both the veneering porcelain and the core whereas the Digident CAD/CAM zirconia crowns showed fracture only of the veneering porcelain.

CONCLUSION

The fracture strengths of CAD/CAM zirconia crowns differ depending on the compatibility of the core material and the veneering porcelain.  相似文献   
8.

PURPOSE

Marginal fit is a very important factor considering the restoration''s long-term success. However, adding porcelain to copings can cause distortion and lead to an inadequate fit which exposes more luting material to the oral environment and causes secondary caries. The purpose of this study was to compare the marginal fit of 2 different all-ceramic crown systems before and after porcelain veneering. This study was also intended to verify the marginal fit of crowns originated from green machining of partially sintered blocks of zirconia (Lava CAD/CAM system) and that of crowns obtained through machining of fully sintered blocks of zirconia (Digident CAD/CAM system).

MATERIALS AND METHODS

20 crowns were made per each system and the marginal fit was evaluated through a light microscope with image processing (Accura 2000) at 50 points that were randomly selected. Each crown was measured twice: the first measurement was done after obtaining a 0.5 mm coping and the second measurement was done after porcelain veneering. The means and standard deviations were calculated and statistical inferences among the 2 groups were made using independent t-test and within the same group through paired t-test.

RESULTS

The means and standard deviations of the marginal fit were 61.52 ± 2.88 µm for the Digident CAD/CAM zirconia ceramic crowns before porcelain veneering and 83.15 ± 3.51 µm after porcelain veneering. Lava CAD/CAM zirconia ceramic crowns showed means and standard deviations of 62.22 ± 1.78 µm before porcelain veneering and 82.03 ± 1.85 µm after porcelain veneering. Both groups showed significant differences when analyzing the marginal gaps before and after porcelain veneering within each group. However, no significant differences were found when comparing the marginal gaps of each group before porcelain veneering and after porcelain veneering as well.

CONCLUSION

The 2 all-ceramic crown systems showed marginal gaps that were within a reported clinically acceptable range of marginal discrepancy.  相似文献   
9.

Objectives

To characterise the mechanical properties of the machinable polymers Pekkton® (Cendres-Meteaux, Biel/Bienne, Switzerland), Lava Ultimate® (3MESPE, Seefeld, Germany), Vita Enamic® (Ivoclar Vivadent, Schaan, Liechtenstein) and the ceramic IPS e.Max Press® (Ivoclar Vivadent, Schaan, Liechtenstein). To determine the structural integrity of full coverage crowns fabricated from these materials.

Methods

The following tests were conducted: Biaxial flexural strength (BFS) using the piston on 3 balls jig (n = 10); Vickers Hardness (VH) 10 indentations per sample with 10 kg load & 20 s dwell time (n = 5); Hygroscopic Expansion Change (HEC) in artificial saliva over 68 days (n = 5). Structural Strength (SS) of teeth analogues (n = 20) restored with monolithic crowns from the four materials. Mean values and standard deviations for BFS, VH, HEC and SS tests were calculated and compared using one-way ANOVA with post-hoc Tukey’s test at a level of 5% significance.

Results

BFS: IPS e.Max Press® (317 MPa ± 37 MPa), Pekkton® (227 MPa ± 18 MPa), Lava Ultimate® (145 MPa ± 18 MPa) and Vita Enamic® (137 MPa ± 7 MPa) with a significance between groups of p < 0.0001. VH: IPS e.Max Press® (5064 MPa ± 131 MPa), Vita Enamic® (1976 MPa ± 12 MPa), Lava Ultimate® (924 MPa ± 27 MPa) and Pekkton® (445MPa ± 21 MPa) with a significance between groups of p < 0.0001. HEC (%vol change): Pekkton® (0.14% ± 0.14%), Vita Enamic® (0.38% ± 0.16%) and Lava Ultimate® (1.06% ± 0.17%). SS for full-coverage crowns: Pekkton® (2037 N ± 49 N no fracture), IPS e.Max Press® (1497 N ± 165 N), Lava Ultimate® (1476 N ± 142 N) and Vita Enamic® (1127 N ± 108 N).

Significance

The properties investigated suggest that full coverage monolithic PEKK crowns possess adequate mechanical and physical properties for use in the posterior region of the mouth. These results must be considered alongside other data including clinical studies.  相似文献   
10.

Objective

To evaluate the fatigue failure load, number of cycles until failure, and survival probability of adhesively cemented materials with different microstructures (glass-, hybrid- and resin-ceramic) used to manufacture CAD/CAM monolithic restorations.

Methods

Disc-shaped specimens (n = 15; Ø = 10 mm; thickness = 1.0 mm) were produced from CAD/CAM blocks as follows: feldspathic (FEL); leucite (LEU); lithium disilicate (LD); zirconia-reinforced lithium silicate (ZRLS); polymer-infiltrated ceramic network (PICN); and resin nanoceramic (RNC). Adhesive cementation was performed onto epoxy discs (dentin analogue- Ø = 10 mm; thickness = 2.5 mm). The cemented assemblies were subjected to fatigue testing using a step–stress approach (400 N–2200 N; step-size of 200 N; 10,000 cycles per step; 1.4 Hz). Fatigue data were analyzed using Kaplan–Meier and Mantel–Cox (log-rank) tests (p < 0.05) and Weibull statistical analysis. Fractographic analysis was also performed.

Results

All RNC specimens survived the fatigue test (100% probability of survival at 2200 N; 100,000 cycles) and presented occlusal deformation in response to loading, while all other tested materials failed in distinct loading steps with radial cracks starting from the bonding surface. LD (1146.7 N; 47,333) and ZRLS (1013.3 N; 40,666) materials obtained the highest fatigue failure loads and cycles until failure, meanwhile all PICN specimens failed during the first step (0% probability of survival at 400 N; 10,000). FEL had similar Weibull modulus to LD and ZRLS and higher than LEU for both load and number of cycles outcomes.

Significance

The microstructure of adhesively cemented glass-, hybrid- and resin-ceramic CAD/CAM restorative materials influence their response during fatigue testing, which aids in suggesting the best clinical indications.  相似文献   
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