全文获取类型
收费全文 | 1882篇 |
免费 | 140篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 7篇 |
妇产科学 | 7篇 |
基础医学 | 177篇 |
口腔科学 | 21篇 |
临床医学 | 108篇 |
内科学 | 165篇 |
皮肤病学 | 16篇 |
神经病学 | 57篇 |
特种医学 | 30篇 |
外科学 | 67篇 |
综合类 | 342篇 |
预防医学 | 578篇 |
眼科学 | 6篇 |
药学 | 314篇 |
中国医学 | 100篇 |
肿瘤学 | 40篇 |
出版年
2023年 | 16篇 |
2022年 | 41篇 |
2021年 | 56篇 |
2020年 | 52篇 |
2019年 | 39篇 |
2018年 | 34篇 |
2017年 | 35篇 |
2016年 | 63篇 |
2015年 | 70篇 |
2014年 | 117篇 |
2013年 | 139篇 |
2012年 | 155篇 |
2011年 | 147篇 |
2010年 | 94篇 |
2009年 | 95篇 |
2008年 | 85篇 |
2007年 | 104篇 |
2006年 | 66篇 |
2005年 | 65篇 |
2004年 | 52篇 |
2003年 | 40篇 |
2002年 | 27篇 |
2001年 | 43篇 |
2000年 | 46篇 |
1999年 | 25篇 |
1998年 | 17篇 |
1997年 | 34篇 |
1996年 | 27篇 |
1995年 | 24篇 |
1994年 | 22篇 |
1993年 | 10篇 |
1992年 | 12篇 |
1991年 | 21篇 |
1990年 | 16篇 |
1989年 | 11篇 |
1988年 | 10篇 |
1987年 | 9篇 |
1986年 | 13篇 |
1985年 | 9篇 |
1984年 | 8篇 |
1982年 | 9篇 |
1981年 | 6篇 |
1980年 | 9篇 |
1979年 | 5篇 |
1977年 | 5篇 |
1976年 | 7篇 |
1975年 | 10篇 |
1974年 | 8篇 |
1973年 | 11篇 |
1972年 | 9篇 |
排序方式: 共有2045条查询结果,搜索用时 11 毫秒
1.
Distribution patterns of transforaminal injections in the cervical spine evaluated by multi-slice computed tomography 总被引:1,自引:1,他引:0
Transforaminal injections are sometimes used for the diagnosis and treatment of painful conditions in the lumbar and to a lesser degree in the cervical spine. The technique is most often used when investigating/treating radiculopathy caused by degenerative disease. But how selective are the nerve root blocks? What possible structures other than the intended nerve root are affected from such injections? This study was undertaken in order to try to answer these questions, as no study focusing on the possible spread from the transforaminal selective nerve root blocks in the cervical spine has been performed earlier. In three groups of patients, each group including three patients, we injected three different volumes (0.6, 1.1 and 1.7 ml) with a transforaminal technique in the cervical spine. In all the injections, a small amount of contrast media was added. The spread of the injections were then investigated using multi-slice computed tomography with reconstructions. The imaging revealed a possible effect on other nerve roots than the intended ones when a larger volume was used for the root blocks. The spread was related to the injected volume as well as to local anatomy (size of foraminal area). In this study, only 0.6-ml injections could be accepted for being selective enough for diagnostic investigations. 相似文献
2.
The effects of various metal cations and pH on the adsorption of uranium(VI) on strongly acidic cation exchanger Amberlite IR-118H (AIR-118H) were studied. The metal cations suppress U(VI) adsorption differently depending on their ionic radii. Adsorption of U(VI) on AIR-118H peaks at pH 3.4, which was attributed to the occurrence of different forms of U(VI) at different pH values. The adsorption data were then processed using the Frumkin–Fowler–Guggenheim equation, and the standard free energy of adsorption was calculated. 相似文献
3.
本文复习了我国37年(1949~1985)来自各地区报道的155 122株痢疾杆菌。分析菌群分布表明,平均仍以B亚群所占比例最高(80.5%),但八十年代以来有所下降(68.1%)。B亚群中流行亚群是2a与lb;但1a与2b比例有增加趋势。西北和中南地区A亚群比例近来明显增高,提示有关地区环境污染严重,饮水卫生差,亦可能与细菌毒力变异有关,防治中需特别注意。B:D亚群比值以华东地区最低,该比值同经济文化发达水平有一定关系。 相似文献
4.
创收工资—医院按劳分配的探索 总被引:1,自引:1,他引:0
遵循“各尽所能,按劳分配”的社会主义分配原则,我院对职工分配进行了积极的探索。从80年代初起,在院内实行定量、定质的超额劳务提成。但随着医院改革不断深化,医院总收入增加,院内、外独立核算,限期还本息项目增多,原超额劳务提成办法不能适应医院发展。因此,在原有基本工资、奖励工资基础上,增设了创收工资,医院对创收工资从质量、数量、文明建设、医德医风建设等方面进行宏观调控。创收工资使科主任责、权、利落到实 相似文献
5.
本文对5105例乙肝三系统检测结果的32种组合形式出现率进行了统计分析,并引 入年龄因素分层分析。分析讨论了19岁以下、20~39岁、40~59岁及60岁以上四组受检者乙肝三系 统检测结果表现与分布的异同,并据此结合文献报道资料提出了预防处理意见。 相似文献
6.
本文报告不同种的金银花中微量生物元素的分布规律:不同种的金银花中微量生物元素含量的对数与其元素的原子序数成线性关系,并呈现周期性。 相似文献
7.
MIC distribution data were obtained from a variety of international sources, and pooled after selection by a defined criterion. Sixty-seven of these datasets were subjected to a range of statistical goodness-of-fit tests. The log-normal distribution was selected for subsequent modelling. Cumulative counts of MIC distribution data were fitted to the cumulative log-normal distribution using non-linear least squares regression for a range of data subsets from each antibiotic-bacterium combination. Estimated parameters in the regression were the number of isolates in the subset, and (the log(2) values of) the mean and standard deviation. Optimum fits for the cumulative log-normal curve were then used to determine the wild-type MIC range, determined by calculating the MICs associated with the lower and upper 0.1% of the distribution, rounding to the nearest two-fold dilution, and calculating the probabilities of values higher and lower than these values. When plotted logarithmically, histograms of MIC frequencies appeared normal (Gaussian), but standard goodness-of-fit tests showed that the two-fold dilution grouping of MICs fits poorly to a log-normal distribution, whereas non-linear regression gave good fits to population (histogram) log-normal distributions of log(2) MIC frequencies, and even better fits to log-normal cumulative distributions. Optimum fits were found when the difference between the estimated and true number of isolates in the fitted subset was minimal. Sixteen antibiotic-bacterium datasets were fitted using this technique, and the log(2) values of the means and standard deviations were used to determine the 0.1% and 99.9% wild-type cut-off values. When rounded to the nearest two-fold dilution, > or = 98.5% of MIC values fall within the cut-off value range. Non-linear regression fitting to a cumulative log-normal distribution is a novel and effective method for modelling MIC distributions and quantifying wild-type MIC ranges. 相似文献
8.
The distribution kinetics of a novel potent immunosuppressant, FK-506 (FK) has been studied in comparison with cyclosporin A (CyA) both in vivo and in vitro using blood specimens. The infusion studies on FK, 5.0 mg kg-1 through the portal and femoral veins showed that the mean hepatic extraction ratio of FK was 27.9 per cent. The effect of clamping both the hepatic artery and the portal vein on the plasma disappearance profiles of FK, 5.0 mg kg-1, and CyA, 3.5 mg kg-1 was studied. The plasma disposition kinetics of CyA was almost the same as in the normal rats. However, the plasma FK levels were about 10 times higher than those obtained in the control group rats. This difference is attributed to the restricted initial distribution of FK to the liver, because the volume of the initial distribution space, V1, of FK was about 10 times smaller than that obtained in normal rats. In in vitro experiments, drug distribution was studied in blood samples (2.0 ml) spiked with FK or CyA, 1.0 micrograms ml-1. The plasma drug levels measured at 2 min after drug administration were 0.842 +/- 0.012 micrograms ml-1 and 0.769 +/- 0.047 micrograms ml-1 for FK and CyA, respectively. The distribution volume in the blood compartment, VB, was determined by dividing the spiked amount of drugs with these plasma concentrations. The VB was 2.38 +/- 0.04 ml for FK and 2.62 +/- 0.16 ml for CyA. There was no significant difference in VB between FK and CyA. The plasma free fraction, fp of the drugs was measured by the equilibrium dialysis method. For FK, the mean fp values (+/- SE) were 1.31 +/- 0.18 per cent (2.0 micrograms ml-1) and 1.93 +/- 0.18 per cent (5.0 micrograms ml-1). For CyA, the fp values were 4.85 +/- 0.36 per cent (1.0 micrograms ml-1) and 5.75 +/- 0.82 per cent (5.0 micrograms ml-1). The hydrophobicity parameter, logP' determined through the HPLC method was 0.386 for FK and 0.545 for CyA. Although FK was less hydrophobic than CyA, its protein binding was higher than CyA. 相似文献
9.
Intravenously injected polystyrene microspheres with functional amino groups (AP-MSs, 0.2,1.0, and 4.0 urn in diameter) were cleared from the blood very rapidly. The calculated half-lives for 0.2-, 1.0-, and 4.0-μm AP-MSs were about 55,60, and 50s; no significant differences were found with 106,107, and 108 microspheres/rat. Loading experiments showed that the liver, spleen, lung, kidney, and heart had a very high capacity to take up AP-MSs. The AP-MSs were distributed mainly to the liver, lung, and spleen, whereas other organs contained less than 1 % of injected AP-MSs. In terms of numbers of AP-MSs per gram of tissue, the highest contents were found in spleen, liver, and lung for 0.2-, 1.0-, and 4.0-um AP-MSs, respectively. There was indication of redistribution of particles from one organ to another during the first 6 h after injection. Chondroitin sulfate A (Chon) and hyaluronic acid (Hya) adsorbed or covalently linked to AP-MSs increased uptake in the liver, with Chon AP-MSs (adsorbed or linked) showing the best effect: about 25% increase compared with unadsorbed 1-μm AP-MSs. Experiments with separated cells in vitro demonstrated that 1 um AP-MSs, intravenously injected, associated only with Kupffer cells. When the microspheres were adsorbed with Chon, there was also association with liver endothelial cells. This finding indicates that conjugation of microspheres with ligands for endothelial receptors may be a useful method for directing microspheres to specific organs, even if the receptors are not by themselves phagocytic 相似文献
10.
内蒙古啮齿动物分布聚类区初步探讨 总被引:1,自引:0,他引:1
赵天Fong 《中国媒介生物学及控制杂志》1995,6(1):28-32
本文将内蒙古55种啮齿动物在本自治区8个动物地理省中的有或无分布作为二元属性,表征动物地理省间种类组成的相似性用联合系数表示,并以类平均法进行聚类。根据聚类结果,讨论了分布聚类与动物地理区划的关系。 相似文献