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1.
法半夏罗汉果川贝枇杷膏与强力枇杷露药理作用的比较研究 总被引:3,自引:0,他引:3
法半夏罗汉果川贝枇把膏与强力批他露均有镇咳祛痰作用,罗汉果川贝枇把膏尚能平喘抗炎。 相似文献
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符文琛 《工业卫生与职业病》1987,(1)
通过对冶金、锻造、铸造、陶瓷、纺织、印染、铁路、航运等行业的16个作业环境热环境参数和工人生理反应关系的调查,对现行的高温作业分级标准不足之处提出了一些看法,并认为IS0提出的热环境下机体反应的阈限值对我国亦是适宜的。经统计学分析发现,作业环境的计算温度和工人平均体温之间有明显相关(r=0.86)。不同气温下464名工人的主观感觉调查表明,35℃时100%的工人都有热或很热的感觉。 相似文献
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《Immunity》2021,54(11):2481-2496.e6
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A strong promoter of bacteriophage MB78 does not have minus 35 consensus sequence although it has a TGn motif immediately
upstream of minus 10 sequence as well as the AT rich UP element. It is efficiently recognised by the sigma 70 RNA polymerase,
however, a phage-specific factor competes with sigma 70 RNA polymerase for binding to this region, the binding of the factor
being stronger than that of the polymerase. Contrary to the reports in the literature the polymerase appears not to bind to
the UP element whereas the phage-specific factor does. The latter seems to be involved in the regulation of the promoter activity.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
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Chien-Chun Liu Ya-Han Yang Yung-Chin Hsiao Po-Jung Wang Jo-Chuan Liu Chien-Hsin Liu Wen-Chin Hsieh Chih-Chuan Lin Jau-Song Yu 《Toxins》2021,13(2)
Snake envenomation is a serious public health issue in many tropical and subtropical countries. Accurate diagnosis and immediate antivenom treatment are critical for effective management. However, the venom concentration in the victims’ plasma is usually low, representing one of the bottlenecks in developing clinically applicable assays for venom detection and snakebite diagnosis. In this study, we attempted to develop a simple method for rapid enrichment of venom proteins from human plasma to facilitate detection. Our experiments showed that several major protein components of both Naja atra (N. atra) and Bungarus multicinctus (B. multicinctus) venoms have higher isoelectric point (pI) values relative to high-abundance human plasma proteins and could be separated via strong cation exchange–high-performance liquid chromatography (SCX-HPLC). Based on this principle, we developed an SCX tip column-based protocol for rapid enrichment of N. atra and B. multicinctus venom proteins from human plasma. Application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) led to the identification of cytotoxin and beta-bungarotoxin as the major proteins enriched by the SCX tip column in each venom sample. The entire process of venom enrichment could be completed within 10–15 min. Combination of this method with our previously developed lateral flow strip assays (rapid test) significantly enhanced the sensitivity of the rapid test, mainly via depletion of the plasma protein background, as well as increase in venom protein concentration. Notably, the SCX tip column-based enrichment method has the potential to efficiently enrich other Elapidae snake venoms containing proteins with higher pI values, thereby facilitating venom detection with other assays. This simple and rapid sample preparation method should aid in improving the clinical utility of diagnostic assays for snakebite. 相似文献
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