全文获取类型
收费全文 | 923篇 |
免费 | 35篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 114篇 |
儿科学 | 27篇 |
妇产科学 | 13篇 |
基础医学 | 171篇 |
口腔科学 | 12篇 |
临床医学 | 49篇 |
内科学 | 74篇 |
皮肤病学 | 8篇 |
神经病学 | 64篇 |
特种医学 | 27篇 |
外科学 | 113篇 |
综合类 | 128篇 |
预防医学 | 33篇 |
眼科学 | 20篇 |
药学 | 91篇 |
中国医学 | 24篇 |
肿瘤学 | 18篇 |
出版年
2023年 | 5篇 |
2022年 | 23篇 |
2021年 | 34篇 |
2020年 | 27篇 |
2019年 | 16篇 |
2018年 | 25篇 |
2017年 | 23篇 |
2016年 | 35篇 |
2015年 | 27篇 |
2014年 | 61篇 |
2013年 | 60篇 |
2012年 | 56篇 |
2011年 | 53篇 |
2010年 | 45篇 |
2009年 | 45篇 |
2008年 | 53篇 |
2007年 | 35篇 |
2006年 | 46篇 |
2005年 | 27篇 |
2004年 | 27篇 |
2003年 | 32篇 |
2002年 | 11篇 |
2001年 | 18篇 |
2000年 | 18篇 |
1999年 | 14篇 |
1998年 | 11篇 |
1997年 | 10篇 |
1996年 | 12篇 |
1995年 | 16篇 |
1994年 | 5篇 |
1993年 | 14篇 |
1992年 | 7篇 |
1991年 | 7篇 |
1990年 | 11篇 |
1989年 | 4篇 |
1988年 | 4篇 |
1987年 | 8篇 |
1986年 | 2篇 |
1985年 | 9篇 |
1984年 | 8篇 |
1983年 | 4篇 |
1982年 | 8篇 |
1981年 | 8篇 |
1980年 | 2篇 |
1979年 | 5篇 |
1978年 | 3篇 |
1977年 | 3篇 |
1973年 | 2篇 |
1971年 | 2篇 |
1970年 | 3篇 |
排序方式: 共有986条查询结果,搜索用时 15 毫秒
1.
2.
应用微血管铸型扫描电镜技术研究8例成人肾脏的肾小球微血管构筑,结果发现:1.输入小动脉在肾小球血管极处分为2~5支小球内小叶微动脉。输入小动脉血管铸型的直径为126.35±20.5μm。2.肾小球是由小球内小叶微动脉、毛细血管、毛细血管网小叶间交通支和毛细血管输出根所构成的近似于球状体,小球内每个毛细血管网小叶均是一个独立的机能解剖学单位;3.299个肾小球均有一支输出小动脉,只有一个肾小球有两支输出小动脉。输出小动脉的血管铸型直径为91.35±11.7μm。4.输出小动脉起始处具有毛细血管前括约肌装置,此结构在调控肾小球内的微循环血流有着重要意义。 相似文献
3.
Sérgio Carreir?o Leandro Pereira Marcelo Wilson Rocha Almeida 《Aesthetic plastic surgery》2009,33(3):445-451
Surgical procedures for the mammary region currently are assuming an important role in body-contouring surgery. Enhancement
of results is a constant challenge to the plastic surgeon. A simple and efficient maneuver for resection of the breast’s lateral
pole based on the mammoplasty technique of Professor Ivo Pitanguy is described.
This study realized at the Private Clinic Sérgio Carreir?o, Rio de Janeiro, RJ, Brazil. 相似文献
4.
The Sinding-Larsen and Johansson disease is a non-negligible cause of gonalgia among children of 10 to 14, often misinterpreted as « growing pain . The disease is a benign pathology of the lower pole of the patella which occurs preferentially in physically active children. Our study, carried out in conjunction with the medical department INSEP, is based on a literature review as well as an analysis of 14 cases over two years. The present work eventually led to the differentiation of four etiopathological categories accounting for all the radiochemical evolutions observed. At the origin of these four categories, two factors coexist: the local fragility (the presence of cartilage at the lower pole of the patella) and the trigerring factor, which is most often sports practice. This explains why among children practicing sports, even intensively, only few suffer from this disease.It is essential to know the different radiological aspects of the normal patella in children, in order not to misinterpret one of these aspects with the Sinding-Larsen and Johansson disease.Always benign, the Sinding-Larsen and Johansson disease can very seriously disturb the « careerof children, engaged in high-level sports activity, the average time of evolution being seven months. 相似文献
5.
6.
7.
人源性抗角蛋白单链抗体在巴氏毕赤酵母的分泌表达 总被引:1,自引:0,他引:1
目的:用巴氏毕赤酵母表达人源性抗角蛋白单链抗体。方法:从已构建好的质粒p3MH/ScFv中亚克隆目的片段ScFv并插入酵母表达载体p^PIC9K,构建成重组质粒p^PIC9K/ScFv,并测序鉴定。通过电转将重组质粒p^PIC9K/ScFv整合到巴氏毕赤酵母菌GS115的染色体上。经G418筛选得到高拷贝转化子及Mut表型鉴定后,用含0.5%甲醇的培养基诱导其分泌表达。结果:通过6天的诱导,该系统成功表达了抗角蛋白单链抗体,Western blot实验证实表达产物具有特异性。结论:获得了真核表达的抗角蛋白单链抗体,为其应用研究打下了基础。 相似文献
8.
Ole Holger Petersen 《Pflügers Archiv : European journal of physiology》1971,323(2):91-95
Summary The cat submandibular gland was perfused with a normal NaCl Locke solution and a chloride-free sucrose solution. The numerical increase in acinar membrane potential (secretory potential) was recorded after intra-arterial injection of acetylcholine.There was no significant difference between the size of the secretory potentials recorded during perfusion with the sucrose solution [23.6 mV±1.4 (n=23)] and the size of those recorded during the control periods [20.6 mV±1.2 (n=24)].The maximal value of the membrane potential after injection of acetylcholine was higher [51.8 mV±2.4 (n=23)] during perfusion with the sucrose solution than during the control periods [44.8 mV±1.8 (n=22)].The results show that a pump transporting chloride into the acinar cells cannot be responsible for the generation of the secretory potentials. The results are best accounted for by assuming that an outward passive transport of potassium, being partly short-circuited by an inward passive sodium transport, is responsible for the change in membrane potential after stimulation with acetylcholine.Supported by the Danish State Research Foundation and Johann and Hanne Weimann's legate. 相似文献
9.
Secretory immunoglobulin A and cardiovascular reactions to mental arithmetic, cold pressor, and exercise: effects of alpha-adrenergic blockade 总被引:6,自引:0,他引:6
The mechanism underlying acute changes in secretory immunoglobulin A (sIgA) remains to be determined. In this experiment, sIgA and cardiovascular activity were monitored at rest and while participants performed a mental arithmetic task, cold pressor, and submaximal cycle exercise following placebo or 1 mg of the alpha-adrenergic blocker, doxazosin. Under placebo, the tasks produced patterns of cardiovascular activity indicative of combined alpha- and beta-adrenergic, alpha-adrenergic, and beta-adrenergic activation, respectively. Doxazosin was associated with reduced blood pressure during cold pressor, but not during arithmetic or exercise. Mental arithmetic elicited increases in sIgA concentration and exercise produced increases in both sIgA concentration and secretion rate; these changes were unaffected by alpha blockade. In contrast, the cold pressor was associated with decreases in both sIgA concentration and secretion rate, which were blocked by doxazosin. These data suggest that acute decreases, but not increases, in sIgA are mediated by alpha-adrenergic mechanisms. 相似文献
10.
分泌性中耳炎中耳积液和血清中sIL-2R水平的初步研究 总被引:2,自引:0,他引:2
应用酶联免疫吸附法(ELISA)对30例正常人血清(对照组)和60例分泌性中耳炎患者(SOM组)中耳积液和血清中可溶性白细胞介素2受体(sIL-2R)进行了检测。结果示SOM组血清sIL-2R水平明显高于对照组,MEF中其含量明显高于血清;鼻咽癌组血清及MEF中sIL-2R水平明显高于─般SOM组;粘液组高浆液组;慢性组高于急性组(均P<0.01)。提示:血清及MEF中sIL-2R水平的测定有助于对SOM患者免疫状态的评估;MEF中sIL-2R可能主要由局部中耳粘膜产生;MEP中高浓度的sIL-2R存在可能是SOM迁延不愈的─个原因。 相似文献