全文获取类型
收费全文 | 31826篇 |
免费 | 150篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 302篇 |
儿科学 | 1751篇 |
妇产科学 | 939篇 |
基础医学 | 2825篇 |
口腔科学 | 1564篇 |
临床医学 | 1549篇 |
内科学 | 7964篇 |
皮肤病学 | 719篇 |
神经病学 | 2081篇 |
特种医学 | 793篇 |
外科学 | 6691篇 |
综合类 | 533篇 |
预防医学 | 1498篇 |
眼科学 | 616篇 |
药学 | 1164篇 |
4篇 | |
中国医学 | 80篇 |
肿瘤学 | 928篇 |
出版年
2024年 | 3篇 |
2023年 | 41篇 |
2022年 | 113篇 |
2021年 | 480篇 |
2020年 | 92篇 |
2019年 | 5997篇 |
2018年 | 4464篇 |
2017年 | 2106篇 |
2016年 | 58篇 |
2015年 | 61篇 |
2014年 | 195篇 |
2013年 | 163篇 |
2012年 | 166篇 |
2011年 | 208篇 |
2010年 | 158篇 |
2009年 | 163篇 |
2008年 | 174篇 |
2007年 | 138篇 |
2006年 | 92篇 |
2005年 | 57篇 |
2004年 | 51篇 |
2003年 | 41篇 |
2002年 | 32篇 |
2001年 | 41篇 |
2000年 | 56篇 |
1999年 | 33篇 |
1998年 | 11篇 |
1997年 | 8篇 |
1996年 | 18篇 |
1995年 | 18篇 |
1994年 | 27篇 |
1993年 | 4篇 |
1992年 | 7篇 |
1991年 | 6篇 |
1990年 | 4篇 |
1988年 | 8篇 |
1985年 | 1447篇 |
1984年 | 2269篇 |
1983年 | 1578篇 |
1982年 | 1699篇 |
1981年 | 1619篇 |
1980年 | 1396篇 |
1979年 | 1384篇 |
1978年 | 1143篇 |
1977年 | 870篇 |
1976年 | 1024篇 |
1975年 | 837篇 |
1974年 | 749篇 |
1973年 | 685篇 |
1972年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Conall T. Morgan Brigitte Mueller Varsha Thakur Vitor Guerra Callaghan Jull Luc Mertens Mark Friedberg Fraser Golding Mike Seed Steven E.S. Miner Edgar T. Jaeggi Cedric Manlhiot Lynne E. Nield 《The Canadian journal of cardiology》2019,35(4):453-461
Background
The purpose of the study was to evaluate the association between fetal echocardiographic measurements and the need for intervention (primary coarctation repair, staged coarctation repair, or catheter intervention) in prenatally diagnosed coarctation of the aorta.Methods
A single-centre retrospective cohort study (2005-2015) of 107 fetuses diagnosed with suspected coarctation of the aorta in the setting of an apex-forming left ventricle and antegrade flow across the mitral and aortic valves.Results
Median gestational age at diagnosis was 32 weeks (interquartile range, 23-35 weeks). Fifty-six (52%) did not require any neonatal intervention, 51 patients (48%) underwent a biventricular repair. In univariable analysis, an increase in ascending aorta (AAo) peak Doppler flow velocity (odds ratio [OR], 1.40 [95% confidence interval [CI], 1.05-1.91] per 20 cm/s; P = 0.03) was associated with intervention. No intervention was associated with larger isthmus size (OR, 0.23; P < 0.001), transverse arch diameter (OR, 0.23; P < 0.001), and aortic (OR, 0.72; P = 0.02), mitral (OR, 0.58; P = 0.001), and AAo (OR, 0.53; P < 0.001) z-scores. In multivariable analysis, higher peak AAo Doppler (OR, 2.51 [95% CI, 1.54-4.58] per 20 cm/s; P = 0.001) and younger gestational age at diagnosis (OR, 0.81 [95% CI, 0.70-0.93] per week; P = 0.005) were associated with intervention, whereas a higher AAo z-score (OR, 0.65 [95% CI, 0.43-0.94] per z; P = 0.029) and transverse arch dimension (OR, 0.44 [95% CI, 0.18-0.97]; P = 0.05) decreased the risk of intervention.Conclusions
In prenatally suspected coarctation, the variables associated with intervention comprised smaller AAo and transverse arch size, earlier gestational age at diagnosis, and the additional finding of a higher peak AAo Doppler. 相似文献2.
3.
Eitaro Ito Akihiro Takai Yoshinori Imai Hiromi Otani Yoshihiro Onishi Yosuke Yamamoto Kohei Ogawa Taiji Tohyama Shunichi Fukuhara Yasutsugu Takada 《Surgery》2019,165(2):353-359
Background
Controversy continues as to whether single-incision laparoscopic cholecystectomy, with the somewhat larger incision at the umbilicus, may lead to a worse postoperative quality of life and more pain compared with the more classic 4-port laparoscopic cholecystectomy. The aim of this study was to compare single-incision and 4-port laparoscopic cholecystectomy from the perspective of quality of life.Methods
This study was a multicenter, parallel-group, open-label, randomized clinical trial. A total of 120 patients who were scheduled to undergo elective cholecystectomy were randomly assigned 1:1 into the single-incision laparoscopic cholecystectomy or the 4-port laparoscopic cholecystectomy group and then assessed continuously for 2 weeks during the postoperative period. The primary outcome was quality of life, defined as the time to resume normal daily activities. Postoperative pain was also assessed. To explore the heterogeneity of treatment effects, we assessed the interactions of sex, age, and working status on recovery time.Results
A total of 58 patients in the single-incision group and 53 in the 4-port group (n?=?111, 47 male, mean age 57 years) were analyzed. The mean time to resume daily activities was 10.2 days and 8.8 days, respectively, for single-incision and 4-port laparoscopic cholecystectomy (95% confidence interval –0.4 to 3.2, P?=?.12). Similarly, the time to relief from postoperative pain did not differ significantly between the groups. Statistically insignificant but qualitative interactions were noted; in the subgroups of women, full-time workers, and patients younger than 60 years, recovery tended to be slower after single-incision laparoscopic cholecystectomy.Conclusion
Postoperative quality of life did not differ substantially between single-incision laparoscopic cholecystectomy and 4-port laparoscopic cholecystectomy. Patients younger than 60 years, women, and full-time workers tended to have a somewhat slower recovery after single-incision laparoscopic cholecystectomy. 相似文献4.
初明利 《国际中华应用心理学杂志》2005,2(3):229-230
研究大学生心理素质与思想品德发展的关系,目的在于分析、发现个体在接受教育过程中的心理运动规律,从而提高思想教育的实效性。本文从马克思主义认识论和实践论的观点出发,依据教育心理学的原理,探讨了心理健康教育与思想品德教育的内在联系和相互作用,提出良好的心理素质是大学生思想品德发展的基础的观点。认为品德的形成与人的心理活动息息相关,个体如果没有良好的品德,将影响其心理素质的完善;同样,没有健全的心理素质,思想品德也不能得到很好的发展。只有思想品德教育与心理健康教育协调发展,共同作用,才能收到良好的教育效果。 相似文献
5.
大学生手机短信消费心理研究 总被引:1,自引:0,他引:1
通过自编调查问卷,对400名大学生的手机短信消费情况进行调查和分析,结果发现:①手机短信已成为当代大学生普遍流行的一种交际手段,并更多地在较亲密的群体内部使用,方便和费用低是大学生选择短信进行交际的主要原因;②大学生的手机短信消费具有显著的性别和年级差异;③部分大学生在短信消费中形成了一定的手机依赖和幻听等心理和行为问题。 相似文献
6.
Robert M. Levy Roman Saikovsky Evgeniya Shmidt Alexander Khokhlov Bruce P. Burnett 《Nutrition Research》2009
Flavocoxid (Limbrel), a proprietary mixture of flavonoid molecules (baicalin and catechin), was tested against a traditional nonsteroidal anti-inflammatory drug, naproxen, for the management of the signs and symptoms of moderate osteoarthritis (OA) in humans. Discomfort and global disease activity were used as the primary end points, and safety assessments were also taken for both treatments as a secondary endpoint. In this double-blind study, 103 subjects were randomly assigned to receive either flavocoxid [500 mg twice daily (BID)] or naproxen (500 mg BID) in a 1-month onset of action trial. Outcome measures included the short Western Ontario and McMaster University Osteoarthritis Index, subject Visual Analogue Scale for discomfort and global response, and investigator Visual Analogue Scale for global response and fecal occult blood. Both flavocoxid and naproxen showed significant reduction in the signs and symptoms of knee OA (P ≤ .001). There were no statistically detectable differences between the flavocoxid and naproxen groups with respect to any of the outcome variables. Similarly, there were no statistically detectable differences between the groups with respect to any adverse event, although there was a trend toward a higher incidence of edema and nonspecific musculoskeletal discomfort in the naproxen group. In this short-term pilot study, flavocoxid was as effective as naproxen in controlling the signs and symptoms of OA of the knee and would present a safe and effective option for those individuals on traditional nonsteroidal anti-inflammatory drugs or cyclooxygenase-2 inhibitors. A low incidence of adverse events was reported for both groups. 相似文献
7.
The role of proteolytic enzymes in the hCG-induced increase in testicular vasopermeability and neutrophil extravasation was studied using protease inhibitors. An intra-testicular injection of hCG together with incubation medium conditioned by polymorphonuclear leucocytes (PMNs) caused a significant increase in vasopermeability and a coincident extravasation of PMN's from the postcapillary venules in the rat testis. When p-aminobenzamidine, a serine protease inhibitor which inhibits urokinase-type plasminogen activator, was administered together with hCG in the incubation medium, both the permeability increase and PMN extravasation were prevented. Aprotinin, another serine protease inhibitor, and Eglin C, a specific neutrophil elastase and cathepsin G inhibitor were, however, without effect. None of these inhibitors caused any non-specific vascular effects in the testis at the concentrations used. These results support the concept that the hCG-induced increase in vasopermeability in the rat testis is related to extravasation of PMNs and suggest that urokinase-type plasminogen activator is involved in migration of these cells through the postcapillary venular walls. 相似文献
8.
9.
David C. Sarrett 《The Journal of prosthetic dentistry》1981,46(2):142-144
A technique has been described for utilizing an existing fixed splint in the fabrication of a fixed partial denture to replace splinted teeth that are extracted. 相似文献
10.