全文获取类型
收费全文 | 3675篇 |
免费 | 176篇 |
国内免费 | 79篇 |
专业分类
儿科学 | 142篇 |
妇产科学 | 115篇 |
基础医学 | 632篇 |
口腔科学 | 3篇 |
临床医学 | 185篇 |
内科学 | 174篇 |
皮肤病学 | 6篇 |
神经病学 | 21篇 |
特种医学 | 63篇 |
外科学 | 1673篇 |
综合类 | 348篇 |
预防医学 | 125篇 |
眼科学 | 2篇 |
药学 | 188篇 |
中国医学 | 43篇 |
肿瘤学 | 210篇 |
出版年
2023年 | 20篇 |
2022年 | 43篇 |
2021年 | 82篇 |
2020年 | 81篇 |
2019年 | 84篇 |
2018年 | 58篇 |
2017年 | 80篇 |
2016年 | 72篇 |
2015年 | 76篇 |
2014年 | 154篇 |
2013年 | 177篇 |
2012年 | 120篇 |
2011年 | 143篇 |
2010年 | 136篇 |
2009年 | 170篇 |
2008年 | 179篇 |
2007年 | 184篇 |
2006年 | 193篇 |
2005年 | 157篇 |
2004年 | 185篇 |
2003年 | 134篇 |
2002年 | 141篇 |
2001年 | 116篇 |
2000年 | 102篇 |
1999年 | 73篇 |
1998年 | 78篇 |
1997年 | 67篇 |
1996年 | 63篇 |
1995年 | 64篇 |
1994年 | 52篇 |
1993年 | 45篇 |
1992年 | 37篇 |
1991年 | 37篇 |
1990年 | 42篇 |
1989年 | 45篇 |
1988年 | 49篇 |
1987年 | 44篇 |
1986年 | 40篇 |
1985年 | 41篇 |
1984年 | 34篇 |
1983年 | 31篇 |
1982年 | 40篇 |
1981年 | 39篇 |
1980年 | 31篇 |
1979年 | 14篇 |
1978年 | 42篇 |
1977年 | 6篇 |
1976年 | 16篇 |
1975年 | 6篇 |
1974年 | 3篇 |
排序方式: 共有3930条查询结果,搜索用时 15 毫秒
1.
正阑尾残端瘘是阑尾切除术后严重的并发症之一,其发生率在0.7%~3.7%~([1]),一旦发生,往往不能自愈,治疗周期长,给病人带来严重的身心损害和经济负担。研究认为,70%~80%的病人能够通过冲洗引流、肠内肠外营养支持、内镜下阑尾残端夹闭等方法治愈,但仍有近20%的病人在接受3~6个月的保守治疗仍无法治愈,须接受二次手术~([2])。笔者医院将腹腔镜技术应用于阑尾残端瘘病人的再次手术中。现报告如下。 相似文献
2.
3.
4.
Sami Al-Said Ammar Ali Abdul Kader Alobaidy Emad Mojeeb Abdulla Al-Naimi Ahmed A Shokeir 《International journal of urology》2007,14(5):452-454
Xanthogranulomatous orchitis is an extremely rare inflammatory non-neoplastic destructive lesion of the testis. We report a 44-year-old man who presented with right scrotal swelling and two discharging sinuses. Testicular tumor markers were normal. Scrotal ultrasound showed heterogeneous testicular areas and irregular margin of the tunica. Surgical exploration revealed infected, unhealthy testicular tissue with necrosis and tumor-like lesion. Orchidectomy was done and histopathology showed xanthogranulomatous orchitis. 相似文献
5.
Tsuneharu Miki Yoichi Mizutani Hideyuki Akaza Seiichiro Ozono Taiji Tsukamoto Toshiro Terachi Katsusuke Naito Norio Nonomura Isao Hara Osamu Yoshida The Japan Blood Cell Transplantation Study Group for Testicular Germ Cell Tumor 《International journal of urology》2007,14(1):54-59
OBJECTIVE: Standard chemotherapy shows relatively low long-term survival in patients with poor-risk testicular germ cell tumor (GCT). First-line high-dose chemotherapy (HD-CT) may improve the result. High-dose carboplatin, etoposide, ifosfamide chemotherapy followed by autologous peripheral blood stem cell transplantation (PBSCT) was investigated as first-line chemotherapy in patients with advanced testicular GCT. METHODS: Fifty-five previously untreated testicular GCT patients with Indiana 'advanced disease' criteria received three cycles of bleomycin, etoposide and cisplatin (BEP) followed by one cycle of HD-CT plus PBSCT, if elevated serum tumor markers were observed after three cycles of the BEP regimen. RESULTS: Thirty patients were treated with BEP alone, because the tumor marker(s) declined to normal range. Twenty-five patients received BEP and HD-CT. One patient died of rhabdomyolysis due to HD-CT. Three and six (13% and 25%) out of 24 patients treated with BEP and HD-CT achieved marker-negative and marker-positive partial responses, respectively. The other patients achieved no change. Fifteen (63%) are alive and 14 (58%) are free of disease at a median follow-up time of 54 months. Severe toxicity included treatment-related death (4%). CONCLUSIONS: HD-CT with peripheral stem cell support can be successfully applied in a multicenter setting. HD-CT demonstrated modest anticancer activity for Japanese patients with advanced testicular GCT and was well tolerated. This regimen might be examined for further investigation in randomized trials in first-line chemotherapy for patients with poor-risk testicular GCT. 相似文献
6.
对小鼠睾丸冰冻切片LDH-X的显示方法作了进一步探讨。实验表明,以L-2-羟基-3-甲基戊酸(HMV)为特异性底物,能相当有效地显示睾丸LDH-X的分布,且该底物的配制方法简便易行。在显示LDH-X的孵育液中采用萘酚蓝(NB)作中间递电子体较吩嗪甲基硫酸酯更具优越性。 相似文献
7.
Homologous testis transplantation in dogs 总被引:4,自引:0,他引:4
Evert J. Barten Hayrabet Garybian Pieter J. Klopper Donald W. W. Newling 《Transplant international》1997,10(5):362-368
There is growing interest in the possible use of homologous testis transplantation for the treatment of anorchia and male
infertility. In order to test the surgical and immunological feasibility of this therapy, three series of experimental studies
of homologous testis transplantation were carried out in dogs. In the first pilot study, four beagles from the same litter
were transplanted using microsurgical techniques for end-to-end anastomosis of the testicular vessels and the vas deferens.
These dogs received cyclosporin A (CyA) for 3 months after transplantation. The longest functional graft survival in this
series was 163 days, strongly suggesting that long-term survival of a homologously transplanted testis graft is possible.
A second series of operations was performed on ten mongrel dogs. The same surgical technique was employed and the series was
divided into three groups.
Group 1 received CyA monotherapy, group 2 a combination of CyA and prednisolone, and group 3 received no immunosuppression.
The average graft survival time in this series was 18 days, significantly less than the 71 days in the first series. The dogs
in group 2, however, had graft survival times that were three times longer than those in the other two groups, suggesting
that CyA in combination with prednisolone yields the best graft survival. In the third series, five littermates received a
testis graft after castration. Immunosuppression was achieved by administration of CyA and prednisolone for 3 months. In three
out of five animals, the graft survived until the immunosuppressive therapy was suspended. Histological biopsies of the graft
3 months after transplantation showed the same maturation of sperm cells as in the control testis of the same dog. The results
of the last series suggest that long-term survival of homologously transplanted testis grafts in dogs is, indeed, possible
with the aid of CyA and prednisolone.
Received: 14 August 1996 Received after revision: 21 March 1997 Accepted: 24 April 1997 相似文献
8.
Xenofon Giannakopoulos Panagiotis Chambilomatis loannis Filiadis Agathi Ntourntoufi Styliani Andronikou Alciviadis Kammenos 《International journal of urology》1997,4(3):324-326
Torsions of the spermatic cord occurring from the intrauterine period to the end of the first year of life are termed perinatal. These are divided into prenatal and postnatal torsions, depending on their occurrence in the intrauterine or postuterine period. From January 1984 to January 1996, 6 cases were identified at our institution, involving 4 prenatal and 2 postnatal extravaginal torsions of the spermatic cord. These cases are reviewed with regard to optimal therapeutic approaches for the treatment of both the affected gonad as well as the contralateral one, and whether the event occurred prenatally or postnatally. The authors also propose several clinical indications useful for obstetricians, pediatricians, urologists and nurses. 相似文献
9.
Summary: For the quantitative determination of the testicular size or volume, two groups of apparatus are available: on the one hand, model testes, which are extremely valuable in longitudinal and cross-sectional studies during the period of pubescence, and on the other hand, measuring devices, with which the testicular dimensions can be specified. The latter instruments are helpful chiefly during the adolescent years and the diagnosis of problems surrounding fertility. The testicular volume can be calculated subsequently from the specific testicular measurements. The formula, for computing the volume of an ellipsoid, seems to be the most suitable for this purpose. Appliances also have been developed, which allow the largest (longitudinal) dimension (in mm) and the testicular volume (in cm3) to be read off simultaneously. A tonometer can be useful to quantitatively estimate the testicular consistency, which is a parameter of the testicular integrity at the level of tubular function (spermatozoa production). 相似文献
10.
目的:认识睾丸微石症(TM)的临床意义和诊断方法。方法:回顾性报告2例TM病例的临床资料,结合文献进行讨论。结果:2例分别因左精索静脉曲张和附睾炎就诊的患者行阴囊超声检查时发现睾丸内散在多发点状强回声,如针尖样,1~2mm,后无声影。分别诊断为局部TM、左精索静脉曲张和TM,左附睾炎。甲胎蛋白、人绒毛膜促性腺激素、乳酸脱氢酶和睾酮等检查均正常。对睾丸微石症未做特殊处置,随访6~8个月,体检和睾丸瘤标未见异常,阴囊超声睾丸图像无特征性改变。结论:TM是一种少见、无明显临床症状、相对稳定的疾病。多因阴囊其他疾病行超声检查时偶然发现,其是否属于癌前病变尚有争议,但是定期随访和阴囊超声检查是必要的。 相似文献