全文获取类型
收费全文 | 13132篇 |
免费 | 688篇 |
国内免费 | 166篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 448篇 |
妇产科学 | 52篇 |
基础医学 | 521篇 |
口腔科学 | 5篇 |
临床医学 | 3386篇 |
内科学 | 6065篇 |
皮肤病学 | 10篇 |
神经病学 | 175篇 |
特种医学 | 311篇 |
外科学 | 762篇 |
综合类 | 1291篇 |
预防医学 | 170篇 |
药学 | 611篇 |
2篇 | |
中国医学 | 152篇 |
肿瘤学 | 18篇 |
出版年
2023年 | 186篇 |
2022年 | 257篇 |
2021年 | 406篇 |
2020年 | 361篇 |
2019年 | 346篇 |
2018年 | 392篇 |
2017年 | 218篇 |
2016年 | 280篇 |
2015年 | 352篇 |
2014年 | 780篇 |
2013年 | 747篇 |
2012年 | 609篇 |
2011年 | 719篇 |
2010年 | 646篇 |
2009年 | 658篇 |
2008年 | 591篇 |
2007年 | 698篇 |
2006年 | 656篇 |
2005年 | 578篇 |
2004年 | 470篇 |
2003年 | 348篇 |
2002年 | 308篇 |
2001年 | 348篇 |
2000年 | 311篇 |
1999年 | 275篇 |
1998年 | 241篇 |
1997年 | 248篇 |
1996年 | 185篇 |
1995年 | 215篇 |
1994年 | 175篇 |
1993年 | 166篇 |
1992年 | 162篇 |
1991年 | 139篇 |
1990年 | 113篇 |
1989年 | 83篇 |
1988年 | 85篇 |
1987年 | 68篇 |
1986年 | 90篇 |
1985年 | 80篇 |
1984年 | 95篇 |
1983年 | 46篇 |
1982年 | 53篇 |
1981年 | 28篇 |
1980年 | 37篇 |
1979年 | 29篇 |
1978年 | 19篇 |
1977年 | 13篇 |
1976年 | 23篇 |
1975年 | 15篇 |
1973年 | 18篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
Yuanqing Yao Jun Qian Shunkang Rong Yuwen Huang Bo Xiong Gang Yang Dengqing Zhang Shimin Deng Jie Tan Que Zhu Changming Deng Dichuan Liu Haitao Ran Zhigang Wang Jing Huang 《Ultrasound in medicine & biology》2019,45(2):490-499
Stellate ganglion (SG) modification has been investigated for arrhythmia treatment. In this study, transesophageal SG imaging and intervention were explored using a homemade 30F integrated focused ultrasonic catheter in healthy mongrel canines in vivo. Anatomic details of SGs were ultrasonically imaged and evaluated. SG had a heterogeneous echoic structure and characteristic profiles sketched by hyper-echoic outlines in an ultrasonogram. Left SGs in the experimental group were successfully ablated through the esophagus under ultrasonic guidance provided by the catheter itself. Two weeks after the ablation, the QT and QTc of the experimental group decreased compared with those of the sham group and at baseline (both p values < 0.001). Histologic examination revealed that left SGs were destroyed. No major complications were observed. This approach may be further explored as a method for ganglia remodeling evaluation and as a strategy of ganglia modification for arrhythmia and for other diseases. 相似文献
6.
7.
《Heart, lung & circulation》2019,28(10):1463-1471
8.
9.
Rotary ventricular assist devices (VADs) are less sensitive to preload than the healthy heart, resulting in inadequate flow regulation in response to changes in patient cardiac demand. Starling‐like physiological controllers (SLCs) have been developed to automatically regulate VAD flow based on ventricular preload. An SLC consists of a cardiac response curve (CRC) which imposes a nonlinear relationship between VAD flow and ventricular preload, and a venous return line (VRL) which determines the return path of the controller. This study investigates the importance of a physiological VRL in SLC of dual rotary blood pumps for biventricular support. Two experiments were conducted on a physical mock circulation loop (MCL); the first compared an SLC with an angled physiological VRL (SLC‐P) against an SLC with a vertical VRL (SLC‐V). The second experiment quantified the benefit of a dynamic VRL, represented by a series of specific VRLs, which could adapt to different circulatory states including changes in pulmonary (PVR) and systemic (SVR) vascular resistance versus a fixed physiological VRL which was calculated at rest. In both sets of experiments, the transient controller responses were evaluated through reductions in preload caused by the removal of fluid from the MCL. The SLC‐P produced no overshoot or oscillations following step changes in preload, whereas SLC‐V produced 0.4 L/min (12.5%) overshoot for both left and right VADs. Additionally, the SLC‐V had increased settling time and reduced controller stability as evidenced by transient controller oscillations. The transient results comparing the specific and standard VRLs demonstrated that specific VRL rise times were improved by between 1.2 and 4.7 s ( = 3.05 s), while specific VRL settling times were improved by between 2.8 and 16.1 seconds ( = 8.38 s) over the standard VRL. This suggests only a minor improvement in controller response time from a dynamic VRL compared to the fixed VRL. These results indicate that the use of a fixed physiologically representative VRL is adequate over a wide variety of physiological conditions. 相似文献
10.
Renal Denervation for Treatment of Cardiac Arrhythmias: State of the Art and Future Directions 下载免费PDF全文
JEDRZEJ KOSIUK M.D. SEBASTIAN HILBERT M.D. EVGENY POKUSHALOV M.D. GERHARD HINDRICKS M.D. Ph.D. JONATHAN S. STEINBERG M.D. ANDREAS BOLLMANN M.D. Ph.D. 《Journal of cardiovascular electrophysiology》2015,26(2):233-238
Renal Denervation for Treatment of Cardiac Arrhythmias . It has now been more than a quarter of a century since modulation of the sympathetic nervous system was proposed for the treatment of cardiac arrhythmias of different origins. But it has also been some time since some of the early surgical attempts have been abandoned. With the development of ablation techniques, however, new approaches and targets have been recently introduced that have revolutionized our way of thinking about sympathetic modulation. Renal nerve ablation technology is now being successfully used for the treatment of resistant hypertension, but the indication spectrum might broaden and new therapeutic options might arise in the near future. This review focuses on the possible impact of renal sympathetic system modulation on cardiac arrhythmias, the current evidence supporting this approach, and the ongoing trials of this method in electrophysiological laboratories. We will discuss the potential roles that sympathetic modulation may play in the future. 相似文献