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Vishwa Prakash Raman Tandon Raghav Mantri 《Journal of plastic, reconstructive & aesthetic surgery》2006,59(10):1102-1104
Supragaleal placement of tissue expander for management of alopecia of scalp excludes tough galeal layer so that easier and faster expansion of scalp may be achieved. 相似文献
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Atif M. Hussein Bach Ardalan 《Journal of the European Academy of Dermatology and Venereology》1993,2(3):211-216
Background Alopecia is a common side-effect of cancer chemotherapy. Although this complication has been known for many decades, little progress has been made in its prevention or treatment. Previously, we made the following observations: ( a ) treatment of 8-day-old rats with 1-0-n-arabinofuranosylcytosine (ara-C), doxorubicin, and cyclophosphamide (CYC) produced either total body alopecia (ara-C and CYC) or alopecia confined to the head and proximal part of the neck (doxorubicin); ( b ) Imuvert, a biological response modifier, and interleukin-1 protected against alopecia-induced by ara-C; and (c) neither Imuvert or interleukin-1 protected against CYC-induced alopecia. Objective Experiments were designed to test for agents to protect against CYC-induced alopecia. Methods Agents were tested in the 8-day-old rats as a model for chemotherapy-induced alopecia. Results Mesna and S-2-(3-aminopropylamino)-ethylphospnorothioic acid (WR-2721) did not offer any protection against chemotherapy-induced alopecia. N-Acetylcysterine offered very good protection against alopecia induced by CYC but not that produced by ara-C in the newborn rate animal model. Conclusion N-Acetylcysteine may prove to be important in the prevention of CYC-induced alopecia, but this needs to be tested in the clinical setting. 相似文献
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围刺飞针加电针治疗斑秃128例疗效观察 总被引:10,自引:0,他引:10
目的 :寻找治疗斑秃的有效方法。方法 :将斑秃患者 2 0 8例随机分为 2组。治疗组 1 2 8例采用围刺飞针加电针治疗 ,每日 1次 ,1 5次为一疗程 ;对照组 80例用内服中药治疗。结果 :治疗组总有效率为 86 7% ,对照组为 75 0 % ,两组总有效率比较 ,差异有非常显著性意义 (P <0 0 1 )。结论 :围刺飞针加电针治疗斑秃具有良好效果 ,其进针快 ,疼痛感较轻 ,安全 ,病人易接受 ,在临床上有推广价值。 相似文献
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斑秃患者皮损处T淋巴细胞表型的研究及Fas的表达 总被引:2,自引:0,他引:2
目的 研究斑秃患者皮损处浸润T淋巴细胞的表型及Fas的表达情况。方法 应用免疫组织化学技术检测斑秃患者皮损处CD4和CD8T淋巴细胞及Fas的表达。结果 CD4和CD8:活动期和稳定期斑秃患者皮损处无论是毛囊周围还是血管周围CD4T淋巴细胞浸润数量均明显多于CD8T淋巴细胞 (P <0 .0 5 ) ;斑秃活动期的CD4和CD8T淋巴细胞浸润数量与稳定期和对照组相比较差异有统计学意义 (P <0 .0 5 )。Fas :与对照组相比较 ,斑秃患者皮损处毛囊角质形成细胞Fas的表达例数较多 (P <0 .0 5 )。结论 斑秃患者皮损处浸润T淋巴细胞以CD4T细胞占优势 ;Fas在斑秃皮损处毛囊角质形成细胞异常表达。 相似文献
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《Anais brasileiros de dermatologia》2021,96(6):688-692
BackgroundAlthough COVID-19 pandemic significantly induces mortality, many of the patients who recovered present other medical problems such as alopecias. Telogen effluvium is a common alopecia that is usually related to previous events such as acute febrile diseases, including COVID-19.ObjectiveTo evaluate the characteristics of telogen effluvium in COVID-19.MethodThis cross-sectional study was carried out on 526 patients with documented telogen effluvium that recovered from COVID-19. Demographic data, concurrent alopecia, associated diseases, and COVID-19 severity were recorded. Data were analyzed by appropriate statistical methods.ResultsThe mean age of the 526 patients (410 females, 116 males) was 30.97 ± 9.592 years, with 7.65 ± 1.739 weeks of mean time of alopecia onset. Vitamin D deficiency (24.3%), androgenetic alopecia (78.2%), and grade III COVID-19 severity were the most common findings. Alopecia onset was significantly earlier in the younger age group, females, in hypothyroidism, and more severe coronavirus infection. Higher grade coronavirus infection was significantly seen in males, higher ages, earlier onset, and androgenic alopecia.Study limitationsPerforming a single-center study and considering limited variables.ConclusionAlthough Coronavirus 2 infection can be an important factor in telogen effluvium induction, other factors such as associated diseases, drug intake and emotional stress may also be involved. In the cases of early onset of alopecia, concomitant diseases such as hypothyroidism and severe coronavirus infection can occur, thus, the presence of various factors in telogen effluvium induction should be considered. 相似文献
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