全文获取类型
收费全文 | 27052篇 |
免费 | 2610篇 |
国内免费 | 1756篇 |
专业分类
耳鼻咽喉 | 208篇 |
儿科学 | 298篇 |
妇产科学 | 361篇 |
基础医学 | 3358篇 |
口腔科学 | 393篇 |
临床医学 | 3457篇 |
内科学 | 4123篇 |
皮肤病学 | 289篇 |
神经病学 | 1410篇 |
特种医学 | 933篇 |
外国民族医学 | 12篇 |
外科学 | 3094篇 |
综合类 | 4366篇 |
现状与发展 | 3篇 |
一般理论 | 7篇 |
预防医学 | 1855篇 |
眼科学 | 703篇 |
药学 | 2819篇 |
21篇 | |
中国医学 | 1458篇 |
肿瘤学 | 2250篇 |
出版年
2024年 | 62篇 |
2023年 | 346篇 |
2022年 | 819篇 |
2021年 | 1272篇 |
2020年 | 923篇 |
2019年 | 957篇 |
2018年 | 955篇 |
2017年 | 834篇 |
2016年 | 816篇 |
2015年 | 1148篇 |
2014年 | 1434篇 |
2013年 | 1369篇 |
2012年 | 1879篇 |
2011年 | 1968篇 |
2010年 | 1404篇 |
2009年 | 1058篇 |
2008年 | 1218篇 |
2007年 | 1315篇 |
2006年 | 1361篇 |
2005年 | 1256篇 |
2004年 | 1111篇 |
2003年 | 1258篇 |
2002年 | 1172篇 |
2001年 | 955篇 |
2000年 | 747篇 |
1999年 | 709篇 |
1998年 | 434篇 |
1997年 | 400篇 |
1996年 | 298篇 |
1995年 | 302篇 |
1994年 | 225篇 |
1993年 | 182篇 |
1992年 | 188篇 |
1991年 | 174篇 |
1990年 | 139篇 |
1989年 | 123篇 |
1988年 | 117篇 |
1987年 | 96篇 |
1986年 | 81篇 |
1985年 | 66篇 |
1984年 | 35篇 |
1983年 | 20篇 |
1982年 | 15篇 |
1981年 | 18篇 |
1980年 | 16篇 |
1979年 | 31篇 |
1977年 | 11篇 |
1974年 | 15篇 |
1973年 | 13篇 |
1969年 | 11篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Qing-Yang Que Lin-Cheng Zhang Jia-Qi Bao Sun-Bin Ling Xiao Xu 《World journal of gastrointestinal surgery》2022,14(5):397-408
Over the last 40 years, the incidence and prevalence of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) have continued to increase. Compared to other epithelial neoplasms in the same organ, GEP-NENs exhibit indolent biological behavior, resulting in more chances to undergo surgery. However, the role of surgery in high-grade or advanced GEP-NENs is still controversial. Surgery is associated with survival improvement of well-differentiated high-grade GEP-NENs, whereas poorly differentiated GEP-NENs that may benefit from resection require careful selection based on Ki67 and other tissue bio markers. Additionally, surgery also plays an important role in locally advanced and metastatic disease. For locally advanced GEP-NENs, isolated major vascular involvement is no longer an absolute contraindication. In the setting of metastatic GEP-NENs, radical intended surgery is recommended for patients with low-grade and resectable metastases. For unresectable metastatic disease, a variety of surgical approaches, including cytoreduction of liver metastasis, liver transplantation, and surgery after neoadjuvant treatment, show survival benefits. Primary tumor resection in GEP-NENs with unresectable metastatic disease is associated with symptom control, prolonged survival, and improved sensitivity toward systemic therapies. Although there is no established neoadjuvant or adjuvant strategy, increasing attention has been given to this emerging research area. Some studies have reported that neoadjuvant therapy effectively reduces tumor burden, improves the effectiveness of subsequent surgery, and decreases surgical complications. 相似文献
2.
Jae Yun Ahn Jung Bae Park Sungbae Moon Jae Wan Cho Dong Ho Park 《Ophthalmic epidemiology》2020,27(2):105-114
ABSTRACT
Purpose
Work-related eye injuries have been reported with a variety of epidemiologic and clinical characteristics. We aimed to identify epidemiologic characteristics of work-related eye injuries and risk factors associated with severe injury in a large metropolitan city. 相似文献3.
4.
5.
6.
7.
Bryan E.K. Guevara Suhail Saleem Wan‐Ting Chen Pa‐Fan Hsiao Yu‐Hung Wu 《Journal of cutaneous pathology》2019,46(5):347-352
Lucio phenomenon is an atypical reaction of leprosy, characterized by vasculitic lesions that can mimic antiphospholipid syndrome (APS) clinically. Distinguishing the two can be difficult as antiphospholipid autoantibodies may be present in patients with leprosy. We report on a 32‐year‐old female patient presenting with a sudden onset of fever, hemorrhagic bullae, and skin necrosis on her lower legs. She was treated for APS due to the presence of antiphospholipid antibodies but had an inadequate response. A skin biopsy revealed thrombotic vasculopathy and necrotizing vasculitis associated with aggregation of foam cells in the perivascular area and subcutis, with acid‐fast bacilli in the histiocytes and blood vessel walls. Direct immunofluorescence showed IgM, C3, and fibrinogen deposition in the superficial and deep dermal blood vessels. The pathology confirmed the diagnosis of Lucio phenomenon, and appropriate therapy was given. It is essential to evaluate the patient comprehensively, including clinical, serological, and pathological aspects, to obtain the correct diagnosis. 相似文献
8.
9.
Zhengxian Huang Nan Xie Haichao Liu Yuehan Wan Yue Zhu Ming Zhang Yifan Tao Han Zhou Xiqiang Liu Jinsong Hou Cheng Wang 《Journal of oral pathology & medicine》2019,48(9):788-798
It has been suggested that tumour‐infiltrating lymphocytes (TILs) are associated with the progression of oral squamous cell carcinoma (OSCC). However, the prognostic value of TILs is inconclusive due to the heterogeneity of immune cells within the tumour microenvironment. In this meta‐analysis, we aimed to assess the prognostic value of TILs in OSCC. The PubMed, Cochrane, Embase, Scopus and Web of Science databases were searched up to April 20, 2019, and 33 studies were ultimately included in this meta‐analysis. Our pooled meta‐analysis showed that high infiltration of CD8+ TILs, CD45RO+ TILs and CD57+ TILs favoured better overall survival (OS). However, high infiltration of CD68+ macrophages and CD163+ macrophages was associated with poor prognosis in OSCC. These findings suggest that CD8+ TILs, CD45RO+ TILs, CD57+ TILs, CD68+ macrophages and CD163+ macrophages might serve as novel prognostic factors and therapeutic targets in OSCC. 相似文献
10.
喘鸣是婴幼儿时期呼吸道疾病中最常见的症状,病因很多,并非所有的喘鸣均由哮喘引起。气管、支气管炎及气管、支气管软骨软弱、异物、血管畸形,胸内肿瘤以及支气管淋巴结核等,均可引起喘鸣。分析天津市儿童医院收治的以喘鸣为主要症状的3岁以下婴幼儿196例,其主要病因见表1。表1天津市儿童医院收治的196例以喘鸣为主要症状的婴幼儿喘鸣病因病因例数大气道阻塞气管、支气管异物21气管、支气管淋巴结核51先天性气管、支气管、肺发育畸形12支气管软骨软化3纵隔囊肿和(或)肿瘤19血管畸形1中叶综合征5小气道阻塞毛细支气管炎30以喘息为表型的婴幼… 相似文献