全文获取类型
收费全文 | 627篇 |
免费 | 84篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 10篇 |
妇产科学 | 9篇 |
基础医学 | 90篇 |
口腔科学 | 21篇 |
临床医学 | 53篇 |
内科学 | 107篇 |
皮肤病学 | 43篇 |
神经病学 | 43篇 |
特种医学 | 43篇 |
外科学 | 119篇 |
综合类 | 22篇 |
预防医学 | 43篇 |
眼科学 | 7篇 |
药学 | 63篇 |
肿瘤学 | 27篇 |
出版年
2021年 | 11篇 |
2020年 | 7篇 |
2019年 | 12篇 |
2018年 | 15篇 |
2017年 | 7篇 |
2016年 | 7篇 |
2015年 | 7篇 |
2014年 | 8篇 |
2013年 | 22篇 |
2012年 | 22篇 |
2011年 | 24篇 |
2010年 | 11篇 |
2009年 | 11篇 |
2008年 | 23篇 |
2007年 | 19篇 |
2006年 | 20篇 |
2005年 | 22篇 |
2004年 | 22篇 |
2003年 | 21篇 |
2002年 | 22篇 |
2001年 | 30篇 |
2000年 | 26篇 |
1999年 | 33篇 |
1998年 | 10篇 |
1997年 | 10篇 |
1996年 | 7篇 |
1995年 | 7篇 |
1994年 | 10篇 |
1992年 | 17篇 |
1991年 | 12篇 |
1990年 | 9篇 |
1989年 | 18篇 |
1988年 | 7篇 |
1987年 | 11篇 |
1986年 | 8篇 |
1985年 | 11篇 |
1983年 | 10篇 |
1981年 | 9篇 |
1978年 | 11篇 |
1976年 | 6篇 |
1975年 | 9篇 |
1974年 | 5篇 |
1973年 | 11篇 |
1972年 | 13篇 |
1971年 | 13篇 |
1970年 | 13篇 |
1969年 | 14篇 |
1968年 | 5篇 |
1967年 | 5篇 |
1965年 | 7篇 |
排序方式: 共有711条查询结果,搜索用时 15 毫秒
1.
2.
Effects of a brisk walk on lipoprotein lipase activity and plasma triglyceride concentrations in the fasted and postprandial states 总被引:3,自引:0,他引:3
This study aimed to determine whether changes in plasma heparin-releasable lipoprotein lipase (LPL) activity following a brisk
walk were associated with decreases in fasting and/or postprandial triglyceride (TG) concentrations. Two groups of pre-menopausal
women participated. In one group (fasting study group, n=10), TG concentrations and post-heparin plasma LPL activity were measured in the fasted state on two occasions: ~18 h after
a 2-h treadmill walk at 50% maximal oxygen uptake (exercise trial); and after a day of no exercise (control trial). The other
group (postprandial study group, n=9) undertook two oral fat tolerance tests (blood samples taken fasting and for 6 h after a high-fat meal), with plasma LPL
activity measured 6 h after meal ingestion. Pre-conditions were the same as for the fasting study group (i.e. control and
prior exercise). Prior exercise reduced fasting TG concentrations by 23 (7)% (fasting study group) [mean (SEM)] and by 18
(9)% (postprandial study group) (both P<0.05), and the postprandial TG response by 23 (6)% (postprandial study group) (P<0.01). Plasma LPL activity was not significantly increased by exercise in either the fasting or postprandial study groups.
However, exercise-induced changes in both fasting and postprandial LPL activity were significantly correlated with the respective
exercise-induced changes in fasting TG concentration and the postprandial TG response (r=−0.70 and −0.77 respectively, P<0.05 for both). These data suggest that increased LPL activity may contribute to the hypotriglyceridaemic effect of moderate
exercise, although other mechanisms are also likely to be involved.
Electronic Publication 相似文献
3.
4.
The importance of the extracellular matrix (ECM) in epithelial-mesenchymal interactions in developing organisms is well established. Proteoglycans and interstitial collagens are required for the growth, morphogenesis, and differentiation of epithelial organs and the distribution of these molecules has been described. However, much less is known about other ECM macromolecules in developing epithelial organs. We used confocal microscopy to examine the distribution of laminin, heparan sulfate (BM-1) proteoglycan, fibronectin, and collagen types I, IV, and V, in mouse embryonic salivary glands. Organ rudiments were isolated from gestational day 13 mouse embryos and cultured for 24, 48, or 72 hours. Whole mounts were stained by indirect immunofluorescence and then examined using a Zeiss Laser Scan Microscope. We found that each ECM component examined had a distinct distribution and that the distribution of some molecules varied with culture time. Laminin was mainly restricted to the basement membrane. BM-1 proteoglycan was concentrated in the basement membrane and also formed a fine network throughout the mesenchyme. Type IV collagen was mainly located in the basement membrane of the epithelium, but it was also present throughout the mesenchyme. Type V collagen was distributed throughout the mesenchyme at 24 hours, but at 48 hours was principally located in the basement membrane. Type I collagen was distributed throughout the mesenchyme at all culture times, and accumulated in the clefts and particularly at the epithelial-mesenchymal interface as time in culture increased. Fibronectin was observed throughout the mesenchyme at all times. 相似文献
5.
6.
Dunn RB Guy PM Hardman CS Lewis PA Vetter NJ 《Clinical performance and quality health care》1995,3(3):151-155
OBJECTIVE: To determine whether there was any benefit from a single house call by a health visitor (a public health nurse) to an elderly person after discharge home from a geriatric hospital. METHODS: A randomized controlled trial with blind assessments at 28 days was conducted. Subjects included residents of Bath, England, with an average age of 83 years, who were discharged consecutively from a geriatric hospital to their homes. Intervention was a single visit by a health visitor 72 hours after discharge, to ensure the patient was settled at home, or normal post-discharge care. Outcome measures taken at 28 days by a research nurse included survival, hospital readmissions, nursing home admissions, cognitive and physical function, services requested and supplied, and drug therapy. RESULTS: There were no important differences between the intervention and control groups at 28 days on any of the outcome measurements. The control subjects did better than the study subjects on many of the outcome measures. CONCLUSION: A house call by a health visitor to elderly patients after discharge from geriatric wards does not measurably improve the quality of the discharge. 相似文献
7.
8.
9.
W. Elaine Hardman 《Nutrition Research And Practice》2014,8(3):233-240
Epidemiology studies indicate that diet or specific dietary components can reduce the risk for cancer, cardiovascular disease and diabetes. An underlying cause of these diseases is chronic inflammation. Dietary components that are beneficial against disease seem to have multiple mechanisms of action and many also have a common mechanism of reducing inflammation, often via the NFκB pathway. Thus, a plant based diet can contain many components that reduce inflammation and can reduce the risk for developing all three of these chronic diseases. We summarize dietary components that have been shown to reduce cancer risk and two studies that show that dietary walnut can reduce cancer growth and development. Part of the mechanism for the anticancer benefit of walnut was by suppressing the activation of NFκB. In this brief review, we focus on reduction of cancer risk by dietary components and the relationship to suppression of inflammation. However, it should be remembered that most dietary components have multiple beneficial mechanisms of action that can be additive and that suppression of chronic inflammation should reduce the risk for all three chronic diseases. 相似文献
10.