全文获取类型
收费全文 | 805篇 |
免费 | 49篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 4篇 |
妇产科学 | 2篇 |
基础医学 | 108篇 |
口腔科学 | 7篇 |
临床医学 | 47篇 |
内科学 | 255篇 |
皮肤病学 | 14篇 |
神经病学 | 90篇 |
特种医学 | 11篇 |
外科学 | 135篇 |
综合类 | 2篇 |
预防医学 | 5篇 |
眼科学 | 2篇 |
药学 | 22篇 |
肿瘤学 | 147篇 |
出版年
2023年 | 3篇 |
2022年 | 9篇 |
2021年 | 14篇 |
2020年 | 4篇 |
2019年 | 8篇 |
2018年 | 19篇 |
2017年 | 15篇 |
2016年 | 22篇 |
2015年 | 19篇 |
2014年 | 17篇 |
2013年 | 35篇 |
2012年 | 52篇 |
2011年 | 48篇 |
2010年 | 35篇 |
2009年 | 18篇 |
2008年 | 42篇 |
2007年 | 42篇 |
2006年 | 36篇 |
2005年 | 41篇 |
2004年 | 36篇 |
2003年 | 41篇 |
2002年 | 39篇 |
2001年 | 28篇 |
2000年 | 25篇 |
1999年 | 25篇 |
1998年 | 12篇 |
1997年 | 10篇 |
1996年 | 9篇 |
1995年 | 4篇 |
1994年 | 12篇 |
1993年 | 2篇 |
1992年 | 14篇 |
1991年 | 19篇 |
1990年 | 12篇 |
1989年 | 13篇 |
1988年 | 17篇 |
1987年 | 6篇 |
1986年 | 8篇 |
1985年 | 11篇 |
1984年 | 10篇 |
1983年 | 4篇 |
1981年 | 5篇 |
1979年 | 2篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1971年 | 2篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1966年 | 1篇 |
1901年 | 1篇 |
排序方式: 共有856条查询结果,搜索用时 15 毫秒
1.
Masayoshi Hamawaki Motoharu Narimatsu Hiroshi Yamaguchi Katsuo Nishi Kiyoyuki Eishi 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2003,51(3):110-112
A 10-year-old girl having bilateral subclavian steal associated with severe coarctation of the thoracic aorta and an aberrant
right subclavian artery was found, on admission, to have no difference between upper and lower extremity blood pressure, but
echocardiography revealed severe thoracic aorta coarctation and systolic blood pressure in the carotid arteries exceeding
200 mmHg estimated by Doppler ultrasonography. Magnetic resonance imaging and angiography demonstrated bilateral subclavian
steal without esophageal compression. We reconstructed the aortic arch using the left subclavian artery and a reversed Blalock-Park
procedure, then repaired the coarctation with a 14 mm woven double velor vascular graft. The girl was symptom-free following
uncomplicated recovery from surgery. Doppler ultrasonography 2 weeks after surgery showed the pressure gradient across the
aortic arch had decreased from 180 mmHg to 60 mmHg. This residual gradient at the anastomosis between the ascending aorta
and left subclavian artery may improve as native vessels grow. 相似文献
2.
Manabu Noguchi Hideaki Takai Kiyoyuki Eishi Sunao Atogami 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2004,52(6):318-321
Prosthetic valve endocarditis (PVE) caused by Candida species is associated with high morbidity and mortality. A combination
of surgical resection and antifungal drug therapy is the golden standard for treatment, yet surgical intervention is not possible
in all cases of Candida PVE. We report a case of PVE due to Candida albicans cured by medical treatment alone. This case suggests
that, in some instances, Candida PVE can be managed medically with antifungal therapy. Such a conservative approach should
be applied with caution and necessitates very close follow-up on a long-term basis. 相似文献
3.
Hiroichiro Yamaguchi Kiyoyuki Eishi Shiro Yamachika Kazuyoshi Tanigawa Kenta Izumi Seiji Matsukuma 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2005,53(7):372-376
We describe a case of successful combined repair of the aortic and mitral valves for an indication of active infective endocarditis
involving both valves. Mitral valve repair was achieved by vegetation debridement, fixation of the anterior mitral commissure,
resection and suturing of the posterior mitral leaflet, and posterior annuloplasty with autologous pericardium. Aortic valve
repair was achieved by vegetectomy and commissural plication. Postoperative clinical course was without signs of recurrent
infection, and echocardiogram demonstrated mitral valve competence with trivial aortic regurgitation. We concluded that simultaneous
valve repair is a viable option in the context of active endocarditis. 相似文献
4.
Hiroshi Inada Hiroyuki Horio Kiyomu Ishikawa Hiromichi Yoshikawa Eishi Harasawa Hidehiro Hosaka 《Journal of medical systems》1993,17(3-4):257-266
A filing system for ocular fundscopic image data was developed by using a personal computer for the Twin AMHTS. The development of the system was tried as one of the data transfer system including image data between two similar AMHTSs named the Twin AMHTS through the information network system. The filing system is capable of storing 26782 data of ophthalmoscopic pictures with a data compression mode by using a magneto-optical disk (MOD) whose storage capacity of both sides is 616 MB. It takes no long time for retrieval and display of the image data in the filing system. Good quality of compression and decompression obtained and reproducibility of the ocular fundus picture is favorable regardless of normal or abnormal cases. As a result, it is suggested that the developed system has practical utility although it requires more improvement. 相似文献
5.
6.
Eishi Asano Temenuzhka Mihaylova Csaba Juhász Sandeep Sood Harry T Chugani 《Clinical neurophysiology》2007,118(6):1360-1368
OBJECTIVE: To determine how sleep with central spindles alters the spatial distribution of interictal spike frequency in children with intractable focal seizures, and whether such children have spindles arising from the medial temporal region in addition to the frontal-central region. METHODS: Seventeen children (age: 7 months-17 years) were studied using extraoperative electrocorticography (ECoG). RESULTS: Overall spike frequency across the subdural electrodes was greater during sleep with central spindles compared to wakefulness. In 13 children showing at least 1 spike/min in an electrode, the spatial distribution of spike frequency was similar during wakefulness and sleep; in addition, the spike frequency was greater in the seizure onset zones compared to the non-onset areas, regardless of wakefulness or sleep. Spindles were identified in the medial temporal region during sleep with central spindles in all 17 children. CONCLUSION: Overall spike frequency may be increased by sleep with spindles, but the spatial distribution of spike frequency appears similar during wakefulness and sleep in children with intractable focal seizures. SIGNIFICANCE: Both awake and sleep ECoG may be useful to predict seizure onset zones in children with intractable focal epilepsy. Medial temporal spindles are present in some children with focal epilepsy. 相似文献
7.
Tamiko Takemura Yoshinobu Eishi Shigeru Hatakeyama Yuji Takahashi 《Pathology international》1983,33(1):159-167
An unusual case of Cushing's syndrome of a 59-year-old man with bilateral multinodular adrenal hyperplasia and microadenoma of the pituitary gland is presented. Failure to suppress plasma Cortisol with large doses of dexamethasone may suggest autonomous growth of hyperplastic nodules of the adrenals, which were at first induced by prolonged stimuli of ACTH from the microadenoma of the pituitary gland. ACTH could not be detected in the microadenoma cells on paraffin sections, while Crooke's cells were strongly positive for ACTH. The interrelation between bilateral multinodular adrenal hyperplasia and pituitary microadenoma is discussed. 相似文献
8.
9.
Quantitative Analysis of Mycobacterial and Propionibacterial DNA in Lymph Nodes of Japanese and European Patients with Sarcoidosis 总被引:10,自引:0,他引:10 下载免费PDF全文
Yoshinobu Eishi Moritaka Suga Ikuo Ishige Daisuke Kobayashi Tetsuo Yamada Tamiko Takemura Touichiro Takizawa Morio Koike Shoji Kudoh Ulrich Costabel Josune Guzman Gianfranco Rizzato Marcello Gambacorta Ronald du Bois Andrew G. Nicholson Om P. Sharma Masayuki Ando 《Journal of clinical microbiology》2002,40(1):198-204
The cause(s) of sarcoidosis is unknown. Mycobacterium spp. are suspected in Europe and Propionibacterium spp. are suspected in Japan. The present international collaboration evaluated the possible etiological links between sarcoidosis and the suspected bacterial species. Formalin-fixed and paraffin-embedded sections of biopsy samples of lymph nodes, one from each of 108 patients with sarcoidosis and 65 patients with tuberculosis, together with 86 control samples, were collected from two institutes in Japan and three institutes in Italy, Germany, and England. Genomes of Propionibacterium acnes, Propionibacterium granulosum, Mycobacterium tuberculosis, Mycobacterium avium subsp. paratuberculosis, and Escherichia coli (as the control) were counted by quantitative real-time PCR. Either P. acnes or P. granulosum was found in all but two of the sarcoid samples. M. avium subsp. paratuberculosis was found in no sarcoid sample. M. tuberculosis was found in 0 to 9% of the sarcoid samples but in 65 to 100% of the tuberculosis samples. In sarcoid lymph nodes, the total numbers of genomes of P. acnes or P. granulosum were far more than those of M. tuberculosis. P. acnes or P. granulosum was found in 0 to 60% of the tuberculosis and control samples, but the total numbers of genomes of P. acnes or P. granulosum in such samples were less than those in sarcoid samples. Propionibacterium spp. are more likely than Mycobacteria spp. to be involved in the etiology of sarcoidosis, not only in Japanese but also in European patients with sarcoidosis. 相似文献
10.
Emiko Ono Yuji Maeda Hidenori Tanimoto Yuma Fukutomi Chiyako Oshikata Kiyoshi Sekiya Takahiro Tuburai Naomi Turikisawa Mamoru Otomo Masami Taniguchi Houta Ishii Akihiko Asahina Eishi Miyazaki Tosihide Kumamoto Kazuo Akiyama 《Arerugī》2007,56(6):587-592
BACKGROUND: Recently, it is recognized that the patients of oral allergy syndrome (OAS) to fruits are increasing. However, there are little knowledges of the background, character, and seriousness about these patients in Kanto regions. OBJECTIVE: We aimed to investigate the clinical features of OAS patients to plant origin foods in Kanto regions. METHODS: The patient, who visited Sagamihara National Hospital from 2000 to 2005 and developed some allergic symptoms to plant origin foods, were studied by a questionary survey. RESULTS: As for the 42 subjects, average age are 36 years old, male:female=8:34, merger of other allergic disease is 35 allergic rhinitis of 42 subjects (83%), 34 of asthma (81%), 14 of atopic dermatitis (33%). The causes of OAS symptoms are 32 rose-family fruits, 34 non-rose family fruits, 14 vegetables, 11 nuts, 2 grains subjects. As for the symptom, only in the oral and pharynx symptoms are found in 12, the systemic symptoms is 29, anaphylaxis is 11 subjects. Allergic rhinitis preceded on the 90% subjects with pollinosis, very high rate. On the other hand, the 20% of all subjects have no symptoms of allergic rhinitis. CONCLUSION: A nasal catarrh symptoms went ahead in most of the OAS subjects in Kanto regions. In addition, considering from some patients have no black alder pollinosis and/or are allergic to many non-rose-family fruits at high frequency, there might be a broad cross-reactivity between many pollens other than alder and plant origin foods. 相似文献