以腹痛为首发症状的胸腺类癌一例

患者男性,34岁,因“间断腹痛半月余”入院,在外院行腹部CT检查未见异常。胸部CT检查示：左前上纵隔可见类圆形软组织肿块影,大小约8．0cm×5．0cm×5．0cm,其内密度均匀,增强扫描轻度强化,纵隔内未见肿大淋巴结,气管支气管及肺组织均未见异常,CT检查考虑胸腺瘤可能性大。人院查体：颜面轻度浮肿,     

以皮肌炎为首发症状的食管鳞状细胞癌1例报告

0 引言 皮肌炎(dermatomyositis)是一种主要累及皮肤和横纹肌的自身免疫性结缔组织病.皮肌炎患者往往合并恶性肿瘤,但合并食管癌的病例极其少见[1].我科遇到1例,现报告如下.     

地下工程典型实例氡浓度与防护对策的分析

以某地下工程进行了从施工阶段到使用阶段建设全过程的氡浓度监测为典型实例,对氡浓度测量与氡析出率测量、通风空间测量与封闭空间测量等问题进行了分析探讨,提出了地下工程的防氡对策。     

胸腔内巨大韧带样纤维瘤病一例

患者,男性,46岁,以"间断胸闷3个月余"为主诉入院,患者近3个月来偶感胸闷.于当地医院行体检提示左侧胸腔占位.查体:左侧下肺部呼吸音低,叩诊浊音,右肺呼吸音正常,心界右移,心律齐,未及异常.     

骨髓间充质干细胞促进肺癌转移的机制

BACKGROUND:So far the positive or negative effects of mesenchymal stem cells on tumor growth and metastasis are under discussion. OBJECTIVE:To explore the mechanism of bone marrow mesenchymal cells in promoting lung cancer metastasis. METHODS: Primary rat bone marrow mesenchymal stem cells were obtained by direct adherence method of the whole bone marrow, and differential adherence combined with digestion control method was performed to purify cells. Lung cancer cell lines were cultured, and the effects of bone marrow mesenchymal stem cells on the migration, invasion and metastasis of lung cancer cells were observed by scratch test, cell invasion and migration assays. Orthotopic lung cancer models were established in rats and bone marrow mesenchymal stem cells were seeded onto the left lung of rats. Then, pathological changes of lung tissues were observed at 14 days after transplannation. RESULTS AND CONCLUSION:After the scratch test, the migration rate of lung cancer cells became higher, and the scratches healed with time. And after cell transplantation, the number of migrated lung cancer cells increased, as well as the ability of lung cancer cells penetrating the Matrigel was strengthened. Besides, fibrous connective tissues could be found around the lung cancer tissues, and necrosis with distinct boundary and large tumor nuclei; the metastatic tissues showed obvious infiltration and necrosis with large tumor nuclei. These results suggest that bone marrow mesenchymal stem cells can promote the invasion, migration and metastasis of lung cancer cell lines.       

人脐带间充质干细胞分离鉴定及移植后对肺癌小鼠化疗的影响

BACKGROUND:Mesenchymal stem cells have pluripotent differentiation, and can promote cell engraftment and immune regulation. Therefore, we attempt to use human umbilical cord mesenchymal stem cells as a new source for treatment of lung cancer by exploring cell isolation, identification and transplantation combined with chemotherapy for lung cancer in mice. OBJECTIVE:To investigate the isolation and identification of human umbilical cord mesenchymal stem cells and its transplantation combined with chemotherapy for lung cancer in mice. METHODS: Human umbilical cord mesenchymal stem cells were isolated from fresh umbilical cord of newborns and identified using tissue culture and enzyme digestion. Twenty Balb/C nude mouse models of lung cancer were randomly divided into two groups: mice in chemotherapy group were given chemotherapy, and those in combined group given combination of chemotherapy with human umbilical cord mesenchymal stem cell transplantation. RESULTS AND CONCLUSION:Compared with the chemotherapy group, the gastrointestinal tract was rosy and shiny, intestinal mucosa was smooth and complete, and tumor mass and blood indexes significantly decreased in the combined group (P < 0.05). To conclude, mature human umbilical cord mesenchymal stem cells can be obtained by tissue culture and enzyme digestion, and the cell transplantation combined with chemotherapy can significantly reduce gastrointestinal tract damage and the make peripheral hemogram in a stable level.      

IPSe.maxPress铸瓷全冠修复前后龈沟液中IFN－γ、TNF-α、MMP-2的测定及其临床意义

 目的 探讨IPS e.max Press铸瓷全冠修复对牙周组织的影响。方法 选择IPS e.max Press铸瓷全冠修复患者79例107颗患牙,在修复前和修复后6个月,测定龈沟液(gingival crevicular fluid,GCF)量,并采用酶联免疫吸附试验(ELISA)分别对龈沟液中干扰素-γ(IFN-γ)、肿瘤坏死因子(TNF- α)、基质金属蛋白酶-2(MMP-2)水平进行分析。结果 修复后 GCF量、IFN-γ、TNF- α、MMP-2水平与修复前比较差异无统计学意义(P＞0.05)。结论 IPS e.max Press铸瓷全冠对牙周组织无明显影响,是一种生物相容性良好的修复方式。     

建筑防氡涂料防氡效果的研究

笔者研究了3种水性防氡内墙涂料和水性防氡地面涂层。采用活性炭法和驻极体法2种测量方法检测涂层对氡析出率的影响，并进行了6个月的追踪时效性检测，以检验涂层系统的气密持久性。并进行了防氡涂料的现场应用试验，报道如下。