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目的:研究超声弹性成像和常规超声在诊断甲状腺良恶性结节中的优劣差异。方法:研究对象选取某院2017年1月~2017年10月间收治的甲状腺结节患者82例(104个结节),分别独立使用超声弹性成像技术和常规超声进行检查,记录肿块位置、大小、是否转移等信息,再将病理切片送检,并于术后对比实物肿块。结果:患者术后病理送检结果显示良性结节88例(84.62%),恶性结节16例(15.38%);超声弹性成像与常规超声诊断结果比较,超声弹性成像与常规超声准确度、灵敏度、特异度比较,超声弹性成像显著高于常规超声(P0.05)。结论:综上所述,使用超声弹性成像技术诊断甲状腺良恶性结节准确率高于常规超声,但存在分级重叠等不足,实际使用时应注意。 相似文献
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Objective Comparative evaluation of flow cytometric immunophenotyping in the diagnosis and differentiation of lymphadenopathy,lymphoma and reactive lymphoid hyperplasia. Methods Ninty-nine fine-needle aspiration specimens from patients with tentative clinical lymphoprofierative disorders were consecutively analyzed by both cytology and flow cytometry with histology results as the gold standard. The three color antibodies including CD3,CD3,CD4,CD5,CD10,CD19,CD20,CD23,CD45,K,λ,FMC7 and CD34 were used for cell composition evaluation and cells with abnormal phenotype. Lymphoma cases were classified according to new WHO classification and subtypes were categorized by immunophenotypic analysis. The results from flow cytometry and cytology were compared. Results By cytological study, 40 of 99 cases were diagnosed with lymphoma, 29 cases were diagnosed with metastatic carcinoma, and 30 cases were diagnosed with reactive lymphoid hyperplasia, necrosis or tuberculosis. Among them, 2 non-Hodgkin lymphoma(NHL) cases were misdiagnosed as reactive lymphoid hyperplasia by cytology. Biopsy was performed in 18 cases of NHL including 16 B-NHL and 2 T-NHL By flow cytometry study, 35 of 99 eases were diagnosed with lymphoma, including 4 cases of lymphoblast lymphoma, 1 case of T-cell lymphoma, and 30 eases of other B-NHL For those 30 cases of B-NHL, 28 cases showed monoclonal light chain expression, and k: λ orλ: k atios exceed 3: 1, and B-cell proportion was (73. 2±27. 2)%. Twenty-six cases could be sub-classified by immunophenotyped. Among 16 histologically confirmed B-NHL cases, only 2 cases diagnosed with follicular lymphoma showed discrepancy with flow cytometry results. In all cases diagnosed with reactive lymphoid hyperplasia and metastasis carcinoma , no abnormal lymphocytes can be found, and k: λ or k: λ ratios were less than 3: 1. Conclusions Fine-needle aspiration analysis with flow eytometrie immunophenotyping can be helpful in diagnosis and differential diagnosis as well as sub-classification of NHL 相似文献
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妊娠期血小板减少93例临床分析与护理 总被引:1,自引:0,他引:1
妊娠合并血小板减少症在临床上比较常见,血小板减少症在妊娠中的发生率为7.6%,主要原因有妊娠期血小板减少(gestational thrombocytopenia,GT)、子痫前期、特发性血小板减少性紫癜(ITP);少见的原因有抗磷脂抗体综合征、系统性红斑狼疮、血栓性血小板减少性紫癜等。其中GT约占妊娠合并血小板减少症的68.57%-81%。正确认识GT对妊娠结局的影响,加强围产期处理,对获得良好妊娠结局十分重要。同时,正确鉴别及处理GT,可避免过度治疗以及对母儿造成的不必要的伤害。本文对93例妊娠期血小板减少症患者的临床资料进行回顾性分析,探讨GT的诊断及治疗,以期使临床医师能够正确恰当地评价GT对母儿的风险, 相似文献
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目的:探讨氟西汀联合小剂量奥氮平治疗无精神病症状抑郁症的疗效和安全性。方法:47例无精神病症状的抑郁症患者随机分为对照组(氟西汀)22例和治疗组(氟西汀联合奥氮平)25例,于治疗前、治疗第2周和第4周测评汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)和不良反应量表(TESS)。疗效评价以HAMD减分率为标准,不良反应以TESS评分为标准。结果:HAMD、HAMA评分组间比较差异有统计学意义(P〈0.05或0.01),2组疗效比较差异有统计学意义(P〈0.05),各时期TESS评分组问比较差异无统计学意义(P〉0.05)。结论:抗抑郁剂联合小剂量奥氮平治疗无精神病性症状抑郁症疗效好,安全性高。 相似文献
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Objective Comparative evaluation of flow cytometric immunophenotyping in the diagnosis and differentiation of lymphadenopathy,lymphoma and reactive lymphoid hyperplasia. Methods Ninty-nine fine-needle aspiration specimens from patients with tentative clinical lymphoprofierative disorders were consecutively analyzed by both cytology and flow cytometry with histology results as the gold standard. The three color antibodies including CD3,CD3,CD4,CD5,CD10,CD19,CD20,CD23,CD45,K,λ,FMC7 and CD34 were used for cell composition evaluation and cells with abnormal phenotype. Lymphoma cases were classified according to new WHO classification and subtypes were categorized by immunophenotypic analysis. The results from flow cytometry and cytology were compared. Results By cytological study, 40 of 99 cases were diagnosed with lymphoma, 29 cases were diagnosed with metastatic carcinoma, and 30 cases were diagnosed with reactive lymphoid hyperplasia, necrosis or tuberculosis. Among them, 2 non-Hodgkin lymphoma(NHL) cases were misdiagnosed as reactive lymphoid hyperplasia by cytology. Biopsy was performed in 18 cases of NHL including 16 B-NHL and 2 T-NHL By flow cytometry study, 35 of 99 eases were diagnosed with lymphoma, including 4 cases of lymphoblast lymphoma, 1 case of T-cell lymphoma, and 30 eases of other B-NHL For those 30 cases of B-NHL, 28 cases showed monoclonal light chain expression, and k: λ orλ: k atios exceed 3: 1, and B-cell proportion was (73. 2±27. 2)%. Twenty-six cases could be sub-classified by immunophenotyped. Among 16 histologically confirmed B-NHL cases, only 2 cases diagnosed with follicular lymphoma showed discrepancy with flow cytometry results. In all cases diagnosed with reactive lymphoid hyperplasia and metastasis carcinoma , no abnormal lymphocytes can be found, and k: λ or k: λ ratios were less than 3: 1. Conclusions Fine-needle aspiration analysis with flow eytometrie immunophenotyping can be helpful in diagnosis and differential diagnosis as well as sub-classification of NHL 相似文献
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目的通过动态监测急性白血病(AL)患者血清乳酸脱氢酶(LDH)水平,探讨LDH对AL患者病情监测和预后评估的临床意义。方法回顾分析初诊的1 184例AL患者的2 170例次LDH水平,评估患者LDH水平随疾病进程的变化趋势并探究其与AL的预后和疾病进展的关系,同时分析LDH与血细胞、骨髓白血病细胞比例、白血病融合基因和流式细胞术分型等相关辅助诊断指标的关系。结果 AL患者不同病程阶段的LDH水发平不同,其中初发组及复发组LDH水平明显高于缓解组及正常对照组(P0.05)。缓解组LDH水平有所减低,但仍高于正常对照组(P0.05)。急性淋巴细胞白血病(ALL)组LDH水平明显高于急性髓性白血病(AML)组(P0.05)。与其他AL诊断及预后相关指标比较,LDH与骨髓白血病细胞百分数、白血病相关融合基因、细胞免疫分型等都有相关性(P0.05)。结论不同病程阶段、不同亚型AL患者的血清LDH水平有差异,血清LDH水平可作为AL诊断、疾病进程及疗效评估的辅助指标。 相似文献