全文获取类型
收费全文 | 2647篇 |
免费 | 121篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 37篇 |
儿科学 | 22篇 |
妇产科学 | 20篇 |
基础医学 | 369篇 |
口腔科学 | 36篇 |
临床医学 | 181篇 |
内科学 | 633篇 |
皮肤病学 | 25篇 |
神经病学 | 110篇 |
特种医学 | 159篇 |
外科学 | 509篇 |
综合类 | 44篇 |
预防医学 | 83篇 |
眼科学 | 85篇 |
药学 | 162篇 |
中国医学 | 5篇 |
肿瘤学 | 310篇 |
出版年
2023年 | 13篇 |
2022年 | 59篇 |
2021年 | 70篇 |
2020年 | 32篇 |
2019年 | 45篇 |
2018年 | 55篇 |
2017年 | 60篇 |
2016年 | 56篇 |
2015年 | 57篇 |
2014年 | 61篇 |
2013年 | 92篇 |
2012年 | 141篇 |
2011年 | 151篇 |
2010年 | 86篇 |
2009年 | 81篇 |
2008年 | 139篇 |
2007年 | 159篇 |
2006年 | 166篇 |
2005年 | 161篇 |
2004年 | 135篇 |
2003年 | 116篇 |
2002年 | 120篇 |
2001年 | 45篇 |
2000年 | 34篇 |
1999年 | 33篇 |
1998年 | 34篇 |
1997年 | 47篇 |
1996年 | 25篇 |
1995年 | 21篇 |
1994年 | 21篇 |
1993年 | 15篇 |
1992年 | 25篇 |
1991年 | 21篇 |
1990年 | 28篇 |
1989年 | 21篇 |
1988年 | 27篇 |
1987年 | 28篇 |
1986年 | 36篇 |
1985年 | 29篇 |
1984年 | 16篇 |
1983年 | 23篇 |
1979年 | 13篇 |
1977年 | 14篇 |
1975年 | 15篇 |
1974年 | 17篇 |
1972年 | 15篇 |
1971年 | 12篇 |
1970年 | 17篇 |
1969年 | 19篇 |
1968年 | 13篇 |
排序方式: 共有2790条查询结果,搜索用时 15 毫秒
1.
Koji Matsumoto Masahiro Hoshino Keita Omori Hidetoshi Igarashi Hiromi Matsuzaki Yasuaki Tokuhashi 《Journal of orthopaedic science》2021,26(4):538-542
BackgroundAdjacent vertebral fracture (AVF) is a major complication following Balloon Kyphoplasty (BKP). There is no scoring system for predicting AVF using only preoperative elements. The purposes of this study were to develop a scoring system for predicting early AVF after BKP based on preoperative factors and to investigate the appropriate surgical indication for BKP.MethodsOf 220 patients who underwent BKP at a single institution since 2011, 65 patients over the age of 60 who had undergone a standing whole spine X-ray preoperatively were enrolled. Factors affecting the occurrence of early AVF were examined. A scoring system was created consisting of the factors exhibiting significant differences, and the correlation between the total score and the incidence of early AVF was investigated.ResultsTwenty of the 65 patients (30.8%) had early AVF. In a univariate analysis, age, previous vertebral fracture, pelvic tilt, and Local kyphosis significantly influenced early AVF. In a multivariate logistic regression analysis, age had an odds ratio of 1.136 (95% CI 1.001–1.289), previous vertebral fractures 4.181 (1.01–17.309), and Local kyphosis 1.103 (1.021–1.191). The scoring system was set as follows: ①Age (<75 years: 0 points(P), 75years≦: 1P), ②The number of previous vertebral fractures (0: 0 P, 1: 1P, 2: 2P, 3 or more: 3P), and ③Local kyphosis (<10°: 0P, 10°≦: 1P). There was a correlation between the total score and the incidence of early AVF (r = 0.812, 1P = 0.05). The incidence of early AVF was 6.4% (2 cases/31 cases) for a score of ≦1P and 54.5% (18 cases/33 cases) for a score of ≧2P.ConclusionsThere was a correlation between the total score and the incidence of early AVF. A score of 1 point or less may represent the appropriate surgical indication for BKP. 相似文献
2.
R S Desowitz K K Shida L Pang G Buchbinder 《The American journal of tropical medicine and hygiene》1989,41(6):630-634
This study characterizes a Plasmodium berghei white rat model of P. falciparum malaria in the pregnant human. Seventy-day-old and 114-day-old female rats, given an infecting inoculum at time of mating, had higher parasitemias and a more severe anemia than age- and sex-matched controls. Under these experimental conditions, the parasitemia went to crisis in all animals and there were no fatal infections. In contrast, all animals died when the infection was initiated 7 days after conception, a timing that brought a coincidence of peak parasitemia and term. Pregnancy during the post-crisis subpatent period did not cause recrudescence. At the time of delivery, the parasitemia was consistently higher in the placental (crush smear) blood than in the peripheral (tail) blood. This difference was greatest in animals giving birth shortly before or 1-2 days after the parasitemic crisis. Very young, compact parasite forms predominated in the placental blood, whereas trophozoites predominated in the peripheral blood. 相似文献
3.
4.
Yasuaki Saijo Eiji Yoshioka Tomonori Fukui Mariko Kawaharada Reiko Kishi 《Hypertension research》2006,29(8):589-596
The aim of this study was to investigate whether the metabolic syndrome (MS) was associated with an elevated level of C-reactive protein (CRP) and increased arterial stiffness, and to clarify whether combined MS and CRP data had a stronger relation to arterial stiffness than did MS data alone. Brachial-ankle pulse wave velocity (baPWV), CRP, and conventional risk factors were evaluated in 3,412 men and 854 women. Adjusted mean values of baPWV in men with 0, 1, 2, and > or = 3 components were 1,309, 1,372, 1,422, and 1,462 cm/s, respectively (p for trend <0.001). Adjusted mean values of baPWV in women with 0, 1, 2, and > or =3 components were 1,212, 1,292, 1,357, and 1,391 cm/s, respectively (p for trend <0.001). Adjusted geometric mean concentrations of CRP in men with 0, 1, 2, and > or = 3 components were 0.036, 0.049, 0.059, and 0.076 mg/dI, respectively (p for trend <0.001). Adjusted geometric mean concentrations of CRP in women with 0, 1, 2, and > or = 3 components were 0.023, 0.030, 0.057, and 0.077 mg/dI, respectively (p for trend <0.001). In analyses of adjusted mean values of baPWV according to the number of MS components and according to CRP levels within or without top quartile levels, the p value for the trend was significant (<0.001) in both men and women but, in post hoc analyses, comparing high and low CRP levels in each MS component-number group, no significant difference was found. These results suggest that, for prediction of increased arterial stiffness, combining MS and CRP data has little additive effect compared to the use of MS data alone. 相似文献
5.
MRI of the brain in chronic carbon monoxide poisoning 总被引:3,自引:0,他引:3
We examined 13 patients with chronic carbon monoxide (CO) poisoning by magnetic resonance imaging (MRI); all of them had been in an explosion in a coal mine 25 years previously. Symmetrical globus pallidus lesions were observed in 12, as was degeneration of the white matter, with focal cortical atrophy. The temporal parietal and occipital lobes were usually affected, the parietooccipital region being the most frequently and extensively damaged. Of the 12 patients with white matter degeneration 7 had definitely asymmetrical cortical and subcortical lesions. There were 6 patients with dilated temporal horns, probably due to atrophy of the hippocampal gyri. A history of CO inhalation and an awareness of the typical distributions of lesions are important for recognition of the effects of CO poisoning, especially when patients are in the chronic stage. 相似文献
6.
7.
Koichi Murata Yasuaki Nakagawa Takashi Suzuki Masahiko Kobayashi Seiya Kotani Takashi Nakamura 《Knee surgery, sports traumatology, arthroscopy》2007,15(10):1261-1263
Intraosseous ganglia of the glenoid are rare, and their etiology is unknown. This report describes a case of an intraosseous
ganglion about to cause fracture of the glenoid. The patient was a 61-year-old woman with a painful left shoulder with a limited
range of motion. Her symptoms did not improve after non-operative treatment. Arthroscopic examination showed a cartilage defect
and erosion in the posteroinferior portion of the glenoid, behind which computed tomography (CT) showed a cystic lesion of
the glenoid. There was no communication between the cyst and the joint space. The patient was treated by curettage and an
autogenous cancellous bone graft from the iliac crest. Two years after the operation, the patient was almost free from pain,
and CT showed good integration of the bone graft. 相似文献
8.
In intestinal anastomoses, local blood flow is one of the most important factors contributing to the success of the healing process. While submucosal local blood flow is maintained better in the colon than in the small intestine, the incidence of anastomotic leakage is higher in the former than in the latter. To resolve this conflict, we have examined differences in the reactivity of the intestinal segments toward the application of tension. Anastomosis was performed with a stapler on the jejunum, ileum, and colon of experimental dogs. The anastomotic sites were subjected to tensile loads applied in incremental steps to measure and compare local blood flow, measured by the hydrogen clearance method, in the submucosal layers of the anastomoses in these intestinal segments. The results of these comparative evaluations indicate that, at a tensile stress level of more than 4 g/mm2, local blood flow in the colon is significantly smaller than that in the jejunum and ileum. These findings were corroborated by microangiographical observations carried out during stress application. The microangiographical data suggest that the rate of filling of the contrast medium is lower with colonic anastomosis than with jejunal and ileal anastomoses. In addition, the intraluminal pressure of the colon was higher than that of the small intestine during the induced peristalsis. The different sensitivity of the local microcirculation systems of the intestinal segments to tension may thus be considered one of the factors accounting for the higher incidence of clinical suture failure in colonic than in small intestinal anastomoses. 相似文献
9.
Hiroyoshi Komai Yasuaki Naito Keiichi Fujiwara Yasuzo Noguchi 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2002,50(2):55-58
OBJECTIVE: Since we developed the procedure in 1996, we have now performed 100 pediatric open heart operations using a lower midline skin incision and a minimal sternotomy approach. METHODS AND RESULTS: To elucidate the benefits of this approach, we analyzed these 100 cases retrospectively. There was no death, and no major complication, caused by this approach, and the resulting scarring in each patient is difficult to be seen under a common undershirt. CONCLUSION: This review shows that the technique of a lower midline skin incision and minimal sternotomy approach is a safe reliable and cosmetically advantageous method for a pediatric cardiac operation. 相似文献
10.
Hayato Funiu Rei Kondo Kaori Sakurada Yasuaki Kokubo Shinya Sato Shinjiro Saito Hiroyuki Orita Shigeki Hirooka Takamasa Kayama 《Brain and nerve》2006,58(3):257-261
We encountered a rare case of unilateral internal carotid arterial defect complicated with anterior communicating aneurysm and subclavian artery aneurysm. The patient was a 56-year-old man in whom cerebral angiography and 3D-CTA revealed defects in the right internal carotid artery and the right carotid canal, and an unruptured aneurysm in the anterior communicating artery. In addition, the patient was also found to have an unruptured aneurysm in the right subclavian artery. As both the aneurysms were considered to have a high risk of rupture and such subclavian aneurysms were likely to cause an embolism, radical surgery was performed for each aneurysm. The postoperative course was uneventful, and the patient was discharged without ambulatory limitations. Although the defect in the internal carotid artery is a relatively rare vascular deformity, the incidence of cerebral aneurysm is about 30% in such cases due to the marked hemodynamic stress involved. On the other hand, there have been only two previous case reports of internal carotid arterial defect complicated with a subclavian aneurysm. Moreover, there have been no previous reports of internal carotid arterial defect complicated with both an intracranial aneurysm and a subclavian aneurysm, as observed in the present case. Thus, this case was very rare and is reported here. 相似文献