Postoperative eventration in abdominal injuries

In a work, the experience with treatment of 29 sufferers with abdominal traumas, who underwent relaparotomy for postoperative eventration, is analysed. Sudden soaking of a dressing by serous or serosanguineous fluid, abdominal pain, tachycardia, rising of a body temperature are the most informative symptoms permitting to establish the indications for relaparotomy in postoperative eventration.     

The diagnosis and treatment of respiratory and circulatory disorders in the acute period of gunshot chest wounds]

Principle and method for gravity estimation of wounds, as well as the efficiency index of treatment of breathing and circulatory disorders in patients with chest gunshot injuries were elaborated on the basis of integral body rheography with mathematical modelling. The application of this method gives the possibility to make an opportune estimation and prognostication of the gravity of clinic outcome of chest gunshot injuries, choose the most rational scheme of treatment of breathing and circulatory disorders. The application of integral body rheography increases the quality of secondary surgical care at the phases of medical evacuation.     

Association of exceptional parental longevity and physical function in aging

Offspring of parents with exceptional longevity (OPEL), who are more likely to carry longevity-associated genotypes, may age more successfully than offspring of parents with usual survival (OPUS). Maintenance of physical function is a key attribute of successful aging. While many genetic and non-genetic factors interact to determine physical phenotype in aging, examination of the contribution of exceptional parental longevity to physical function in aging is limited. The LonGenity study recruited a relatively genetically homogenous cohort of Ashkenazi Jewish (AJ) adults age 65 and older, who were defined as either OPEL (having at least one parent who lived to age 95 or older) or OPUS (neither parent survived to age 95). Subjective and objective measures of physical function were compared between the two groups, accounting for potential confounders. Of the 893 LonGenity subjects, 365 were OPEL and 528 were OPUS. OPEL had better objective and subjective measures of physical function than OPUS, especially on unipedal stance (p = 0.009) and gait speed (p = 0.002). Results support the protective role of exceptional parental longevity in preventing decline in physical function, possibly via genetic mechanisms that should be further explored.     

Human immunodeficiency virus type 1 latency model for high-throughput screening

Human immunodeficiency virus type 1 (HIV-1) is not eliminated from patients even after years of antiretroviral therapy, apparently due to the presence of latently infected cells. Here we describe the development of a cell-based system of latency that can be used for high-throughput screening aimed at novel drug discovery to eradicate HIV-1 infection.     

Pharmacoeconomic aspects in the treatment of chronic obstructive bronchitis

AIM: Analysis of pharmacological cost-efficiency at various stages of medical care for patients with chronic obstructive bronchitis (COB). MATERIAL AND METHODS: The cost of COB patients treatment, including that of hospital stay, ambulance call, outpatient treatment, cost of medicines. RESULTS: In direct medical expenditures, the cost of hospital stay is the highest. Most of this money (80%) is spent on management of severe exacerbation of COB in critical care units. CONCLUSION: It would be valid to set up specialized outpatient service for follow-up and treatment of COB patients.