全文获取类型
收费全文 | 713篇 |
免费 | 40篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 13篇 |
妇产科学 | 44篇 |
基础医学 | 70篇 |
口腔科学 | 18篇 |
临床医学 | 77篇 |
内科学 | 153篇 |
皮肤病学 | 20篇 |
神经病学 | 53篇 |
特种医学 | 11篇 |
外科学 | 99篇 |
综合类 | 3篇 |
预防医学 | 91篇 |
眼科学 | 5篇 |
药学 | 52篇 |
中国医学 | 6篇 |
肿瘤学 | 36篇 |
出版年
2023年 | 5篇 |
2022年 | 15篇 |
2021年 | 28篇 |
2020年 | 15篇 |
2019年 | 16篇 |
2018年 | 22篇 |
2017年 | 16篇 |
2016年 | 16篇 |
2015年 | 21篇 |
2014年 | 27篇 |
2013年 | 31篇 |
2012年 | 54篇 |
2011年 | 58篇 |
2010年 | 26篇 |
2009年 | 30篇 |
2008年 | 52篇 |
2007年 | 43篇 |
2006年 | 40篇 |
2005年 | 34篇 |
2004年 | 25篇 |
2003年 | 21篇 |
2002年 | 22篇 |
2001年 | 14篇 |
2000年 | 14篇 |
1999年 | 11篇 |
1998年 | 5篇 |
1997年 | 2篇 |
1995年 | 2篇 |
1992年 | 6篇 |
1991年 | 5篇 |
1990年 | 5篇 |
1989年 | 3篇 |
1988年 | 2篇 |
1987年 | 3篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1981年 | 4篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1977年 | 6篇 |
1976年 | 4篇 |
1975年 | 2篇 |
1974年 | 8篇 |
1973年 | 10篇 |
1972年 | 3篇 |
1971年 | 5篇 |
1970年 | 3篇 |
1969年 | 3篇 |
1967年 | 2篇 |
1966年 | 2篇 |
排序方式: 共有754条查询结果,搜索用时 31 毫秒
1.
Antonio López-Beltrán Alfonso S. Calañas Pilar Jimena Alberto L. Escudero Telma R. Campello Manuel Muñoz-Torres Fernando Escobar-Jiménez Rafael E. Carvia F. F. Nogales 《Virchows Archiv : an international journal of pathology》1997,431(2):149-151
Three further cases of mature benign cystic teratomas of the ovary associated with virilization are added to the three previously
reported in the literature. They were found in postmenopausal, obese, diabetic women aged 52, 61, and 67 years. The patients
presented with hirsutism and voice changes and clitoromegaly was present in one. Testosterone and androstenedione levels were
elevated but promptly regressed after removal of the tumours. Histologically, sheets of stromal luteinized cells were found
peripherally at the interface between the neoplasm and ovarian tissue. Luteinization of ovarian stroma induced by an unknown
factor related to diabetes mellitus is the origin of the virilization.
Received: 8 January 1997 / Accepted: 28 February 1997 相似文献
2.
Iván Alvarez Anna Sureda Maria D Caballero Alvaro Urbano-Ispizua Josep M Ribera Miguel Canales Javier García-Conde Guillermo Sanz Reyes Arranz Maria T Bernal Javier de la Serna José L Díez José M Moraleda Daniel Rubió-Félix Blanca Xicoy Carmen Martínez Marivi V Mateos Jorge Sierra 《Biology of blood and marrow transplantation》2006,12(2):172-183
We report the results of reduced-intensity conditioning allogeneic stem cell transplantation (allo-RIC) in patients with advanced Hodgkin lymphoma (HL). Forty patients with relapsed or refractory HL were homogeneously treated with an RIC protocol (fludarabine 150 mg/m(2) intravenously plus melphalan 140 mg/m(2) intravenously) and cyclosporin A and methotrexate as graft-versus-host disease (GVHD) prophylaxis. Twenty-one patients (53%) had received >2 lines of chemotherapy, 23 patients (58%) had received radiotherapy, and 29 patients (73%) had experienced treatment failure with a previous autologous stem cell transplantation. Twenty patients (50%) were allografted in resistant relapse, and 38 patients received hematopoietic cells from an HLA-identical sibling. Five patients (12%) died from early transplant-related mortality (before day +100 after allo-RIC). One-year transplant-related mortality was 25%. Acute GVHD developed in 18 patients (45%). Chronic GVHD developed in 17 (45%) of the 31 evaluable patients. The response rate 3 months after the allo-RIC was 67% (21 [52%] complete remissions and 6 [15%] partial remissions). Eleven patients received donor lymphocyte infusions (DLIs) for disease relapse. The response rate after DLI was 54% (3 complete remissions and 3 partial remissions). Overall survival (OS) and progression-free survival (PFS) were 48% +/- 10% and 32% +/- 10% at 2 years, respectively. Refractoriness to chemotherapy was the only adverse prognostic factor for both OS (63% +/- 12% versus 35% +/- 13%; P = .05) and PFS (55% +/- 16% versus 10% +/- 9%; P = .006). For patients with failure of a prior autologous hematopoietic stem cell transplantation, results were especially good for those who experienced late relapses (>/=12 months: 2-year OS and PFS were 75% +/- 16% and 70% +/- 18%, respectively). These data suggest that allo-RIC is feasible in heavily pretreated HL patients and has an acceptable early transplant-related mortality. Results are better in patients allografted in sensitive disease. Both responses observed after the development of GVHD and DLI may suggest a graft-versus-HL effect. Allo-RIC has to be considered an effective therapeutic approach for patients who have had treatment failure with a previous autologous hematopoietic stem cell transplantation. 相似文献
3.
Microinjections of amphetamine into the ventrolateral striatum (VLS) elicit a striking behavioral syndrome characterized by compulsive oral and forelimb motor stereotypies. The neural pathways that mediate these behavioral responses downstream from the striatum have not yet been identified. In a series of experiments, we investigated the involvement of the substantia nigra pars reticulata (SNr) and the ventromedial nucleus of the thalamus (VMT) in the mediation of this behavioral syndrome. We demonstrated that lidocaine-induced reversible inactivation of the SNr reduced amphetamine-induced stereotyped biting and gnawing behaviors, suggesting that the nigral output pathway plays a significant role in the expression of these behavioral responses. In turn, injections of lidocaine into the VMT only transiently reduced amphetamine-stimulated biting and increased stereotyped gnawing and paw nibbling, suggesting that the expression of oral stereotypies induced by amphetamine injections into the VLS is not dependent on thalamocortical feedback. 相似文献
4.
5.
6.
Andrea Altschuler Elana Rosenbaum Peter Gordon Sandra Canales Andrew L. Avins 《Supportive care in cancer》2012,20(6):1291-1297
Purpose
Mindfulness-based stress reduction (MBSR), typically taught in eight weekly classes, helps patients cope with illness, including cancer. Current research is almost exclusively based on post-treatment class attendance. Research suggests that short courses and alternative delivery techniques may also be beneficial. This pilot study assessed whether it would be feasible for cancer patients receiving chemotherapy to listen to MBSR audio recordings individually during treatment and at home and evaluate whether the intervention shows preliminary evidence of efficacy to improve patients’ mood and quality of life (QoL). 相似文献7.
José Sanz-Santos Mireia Martínez-Palau Àngels Jaen Ramón Rami-Porta Bienvenido Barreiro Sergi Call Carme Obiols José Manuel González José Ángel De Marcos Montserrat Ysamat Lydia Canales Mireia Serra Josep Belda 《The Annals of thoracic surgery》2021,111(4):1190-1197
- Download : Download high-res image (252KB)
- Download : Download full-size image
8.
9.
BAX and BCL‐2 polymorphisms,as predictors of proliferative vitreoretinopathy development in patients suffering retinal detachment: the Retina 4 project
下载免费PDF全文
![点击此处可从《Acta ophthalmologica. Supplement》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Salvador Pastor‐Idoate Irene Rodríguez‐Hernández Jimena Rojas Itziar Fernández María‐Teresa García‐Gutierrez Jose M. Ruiz‐Moreno Amandio Rocha‐Sousa Yashin D. Ramkissoon Steven Harsum Robert E. MacLaren David G. Charteris Jan C. Van Meurs Rogelio González‐Sarmiento Jose C. Pastor the Genetics on PVR Study Group 《Acta ophthalmologica. Supplement》2015,93(7):e541-e549
10.