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1.
对64例DPN患者,随机分A组32例和B组32例,二周为一疗程。结果A组临床总有效率为68.75%,B组临床总有效率为93.75%,差异有显著性意义(P〈0.01);肌电图正中、腓总神经传导速度(运动和感觉)两组间和组内均有非常显著性差异(P〈0.01);血液流变学两组治疗前后差异非常显著(P〈0.01),而组间无差异(P〉0.05)。结论苦碟子液与弥可保联合应用可明显提高DPN的治疗效果。 相似文献
2.
金兴权 《现代中西医结合杂志》2008,17(3):389-390
目的探讨糖尿病酮症酸中毒(DKA)的诱因及抢救方法,提高对DKA的治愈率,减少病死率。方法对我院近5 a收治的40例DKA患者临床资料进行回顾性总结。结果40例DKA最常见的诱因是感染(25/40),以意识障碍(12/40)、急性腹痛(14/40)等为首发表现,且有16例未曾诊断过糖尿病,采用小剂量胰岛素持续静脉滴注及积极纠正水电解质紊乱,加强抗感染等综合治疗,抢救成功38例(95%)。结论及时诊断、治疗是成功抢救DKA患者的关键。 相似文献
3.
目的 探讨2型糖尿病肾病患者血清C肽水平变化的意义.方法 选取住院2型糖尿病患者120例,按尿白蛋白排泄率大小分成3组,正常白蛋白尿组34例,微量白蛋白尿组40例,临床白蛋白尿组46例,同时设血糖正常健康组30例.测各组空腹血糖、糖化血红蛋白(HbA1c)、空腹血清C肽(FCP),并进行比较分析.结果 微量白蛋白尿组和临床白蛋白尿组患者血清C肽与正常健康组比较,差异有统计学意义[(1.27±0.5)μg/L和(0.32±0.16)μg/L比(2.39±0.22)μg/L,P<0.01];血清C肽水平与尿白蛋白排泄率呈负相关(r=-0.745,P<0.01).结论 血清C肽水平的下降可能参与2型糖尿病肾病发生发展.Abstract: Objective To investigate the change of serum C-peptide level in type 2 diabetic nephrosis patients. Methods We recruited 120 patients with type 2 diabetes. The level of fasting plasma glucose (FBG), glycated hemoglobin (HbA1c), fasting C-peptide (FCP) and urinary albumin excretion rate (UAER) were measured.According to UAER, 120 patients were divided into Group Ⅰ: normal albuminuria group, 34 patients; Group Ⅱ:microalbuminuria group, 40 patients; Group Ⅲ: clinical albuminuria, 46 patients. At same time, we selected 30 healthy people as control group. Results The level of C-peptide decreased significantly in Group Ⅱ and Group Ⅲ compared with that of control group (P <0.01 ). The difference of C-peptide level between Group Ⅱ, Group Ⅳ and Group Ⅰ was statistically significant (P < 0.01 ). The level of C-Peptide and urinary albumin excretion rate was negatively correlated (R = -0. 745 ,P < 0. 01 ). Conclusion The decline of serum C-pcptide may be involved in the development of type 2 diabetic nephropathy. 相似文献
4.
Objective To investigate the change of serum C-peptide level in type 2 diabetic nephrosis patients. Methods We recruited 120 patients with type 2 diabetes. The level of fasting plasma glucose (FBG), glycated hemoglobin (HbA1c), fasting C-peptide (FCP) and urinary albumin excretion rate (UAER) were measured.According to UAER, 120 patients were divided into Group Ⅰ: normal albuminuria group, 34 patients; Group Ⅱ:microalbuminuria group, 40 patients; Group Ⅲ: clinical albuminuria, 46 patients. At same time, we selected 30 healthy people as control group. Results The level of C-peptide decreased significantly in Group Ⅱ and Group Ⅲ compared with that of control group (P <0.01 ). The difference of C-peptide level between Group Ⅱ, Group Ⅳ and Group Ⅰ was statistically significant (P < 0.01 ). The level of C-Peptide and urinary albumin excretion rate was negatively correlated (R = -0. 745 ,P < 0. 01 ). Conclusion The decline of serum C-pcptide may be involved in the development of type 2 diabetic nephropathy. 相似文献
5.
不同剂量甲巯咪唑治疗Graves病及其对促甲状腺激素受体抗体的影响 总被引:1,自引:0,他引:1
目的 观察不同剂量甲巯咪唑治疗Graves病的疗效及其对促甲状腺激素受体抗体(TRAb)的影响。方法Graves病患者71例,随机分为小剂量组(36例)和常规剂量组(35例),小剂量组给予甲巯咪唑15mg/d,一次顿服;常规剂量组给予甲巯咪唑30mg/d,分3次口服。比较两组的缓解率、副作用发生率、停药后复发率和TRAb水平。结果治疗后两组缓解率、复发率和TRAb水平比较差异均无显著性(均为P>0.05),但小剂量组的不良反应发生率显著低于常规剂量组。结论对大多数Graves病患者,小剂量甲巯咪唑顿服治疗疗效确切,且副作用少。 相似文献
6.
Objective To investigate the change of serum C-peptide level in type 2 diabetic nephrosis patients. Methods We recruited 120 patients with type 2 diabetes. The level of fasting plasma glucose (FBG), glycated hemoglobin (HbA1c), fasting C-peptide (FCP) and urinary albumin excretion rate (UAER) were measured.According to UAER, 120 patients were divided into Group Ⅰ: normal albuminuria group, 34 patients; Group Ⅱ:microalbuminuria group, 40 patients; Group Ⅲ: clinical albuminuria, 46 patients. At same time, we selected 30 healthy people as control group. Results The level of C-peptide decreased significantly in Group Ⅱ and Group Ⅲ compared with that of control group (P <0.01 ). The difference of C-peptide level between Group Ⅱ, Group Ⅳ and Group Ⅰ was statistically significant (P < 0.01 ). The level of C-Peptide and urinary albumin excretion rate was negatively correlated (R = -0. 745 ,P < 0. 01 ). Conclusion The decline of serum C-pcptide may be involved in the development of type 2 diabetic nephropathy. 相似文献
7.
目的探讨C肽变化与糖尿病周围神经病变(DPN)的关系。方法检测120例2型糖尿病(T2DM)患者的空腹血糖、餐后2h血糖、糖化血红蛋白、空腹C肽(FC—P)、餐后2hC肽(2hC—P)、尿微量白蛋白及神经传导速度(NCN)。根据患者有无DPN分为DPN组及非DPN组,按病程分为〈5a组、5-10a组、〉10a组,比较各组C肽水平。结果DPN组2hC—P明显低于非DPN组,且不同病程组两两比较均有统计学差异(P均〈0.05)。与正常者比较,DPN组运动、感觉纤维异常者的NCV及2hC—P均明显降低(P〈0.05或〈0.01)。结论2hC—P水平与T2DM患者的DPN密切相关。 相似文献
8.
对64例DPN患者,随机分A组32例和B组32例,二周为一疗程。结果A组临床总有效率为68.75%,B组临床总有效率为93.75%,差异有显著性意义(P〈0.01);肌电图正中、腓总神经传导速度(运动和感觉)两组间和组内均有非常显著性差异(P〈0.01);血液流变学两组治疗前后差异非常显著(P〈0.01),而组间无差异(P〉0.05)。结论苦碟子液与弥可保联合应用可明显提高DPN的治疗效果。 相似文献
9.
金兴权 《河北中西医结合杂志》2008,(3):389-390
目的探讨糖尿病酮症酸中毒(DKA)的诱因及抢救方法,提高对DKA的治愈率,减少病死率。方法对我院近5a收治的40例DKA患者临床资料进行回顾性总结。结果40例DKA最常见的诱因是感染(25/40),以意识障碍(12/40)、急性腹痛(14/40)等为首发表现,且有16例未曾诊断过糖尿病,采用小剂量胰岛素持续静脉滴注及积极纠正水电解质紊乱,加强抗感染等综合治疗,抢救成功38例(95%)。结论及时诊断、治疗是成功抢救DKA患者的关键。 相似文献
10.
格列美脲联合中效胰岛素治疗2型糖尿病患者应用磺脲类药物继发失效的疗效观察 总被引:1,自引:0,他引:1
目的观察2型糖尿病患者在应用磺脲类药物继发失效后改用格列关脲联合中效胰岛素治疗的临床疗效。方法对56例磺脲类继发失效的2型糖尿病患者,停用原有口服降糖药,改为早餐前服格列美脲,睡前皮下注射中效胰岛素,治疗前后测定血糖、糖化血红蛋白(HbA1c)、胰岛素、C-肽、体质指数及肝肾功能。结果口服格列美脲联合睡前皮下注射中效胰岛素,治疗后空腹血糖、餐后2h血糖、HbA1c均有显著性下降(均P〈0.01),餐后2h、C-肽明显上升(均P〈0.01)。结论格列美脲联合中效胰岛素治疗2型糖尿病磺脲类继发失效,可起到有效控制血糖及改善胰岛B细胞功能的作用。 相似文献